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Update: Botulinum Neurotoxin for the Treatment of Blepharospasm, Cervical Dystonia, Adult Spasticity, and Headache

Practice Guideline, April 2016

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In 2008, the 好色先生 (AAN) published guidelines on the uses of botulinum neurotoxin (BoNT). New research on 4 indications—blepharospasm, cervical dystonia (CD), spasticity, and headache—prompted this update.

Retired on April 7, 2025.

Endorsed by the American Association of Neuromuscular & Electrodiagnostic Medicine and the American Society of Plastic Surgeons.

Clinician Tools and Materials

Companion Publication - Botulinum Neurotoxin - Policy Perspectives

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Companion Publication - Botulinum Neurotoxin - Gaps in Knowledge

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