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2020 Annual Meeting | S39 - Autoimmune and Paraneoplastic Neurological Disorders: Clinical Characteristics and Diagnosis

Wednesday 04/29/20
01:00 PM - 03:00 PM Add To Calendar
This program will be presented both in-person and online
This program is not expected to be available in the meeting's On Demand product.
Scientific Platform Session
Sarosh R. Irani, MD, PhD, FRCP, FEAN, Amanda C. Guidon, MD
Autoimmune Neurology
2.00 CME credits
Event Timeline
01:00 PM - 01:12 PM Abstract 001 - Prospective Assessment of Neuronal Autoimmunity in First Episode of Psychosis
Mar Guasp, MD
01:24 PM - 01:36 PM Abstract 003 - Clinical and Immunological Investigations in Patients with Suspected Autoimmune Post-Herpes Simplex Encephalitis
Juntaro Kaneko
01:36 PM - 01:48 PM Abstract 004 - Sleep Disorders In Anti-NMDAR Encephalitis
01:48 PM - 02:00 PM Abstract 005 - Clinical Significance of Anti-NMDAR Concurrent with Glial or Neuronal Surface Antibodies
Eugenia Martinez-Hernandez, MD
02:00 PM - 02:12 PM Abstract 006 - Population-based Incidence Estimate of Anti-NMDA Receptor Encephalitis in New York City
Anusha Yeshokumar, MD
02:12 PM - 02:24 PM Abstract 007 - Delirium With Catatonic Signs: A Neuropsychiatric Phenotype Associated With Autoimmune Encephalitis?
Cynthia Arely Juarez Jaramillo
02:24 PM - 02:36 PM Abstract 008 - Paraneoplastic Cerebellar Ataxia and Antibodies to Metabotropic Glutamate Receptor 2
02:36 PM - 02:48 PM Abstract 009 - Clinical/ Immunopathological Presentations and Antigen-specific CD8+ T Cell Responses in Paraneoplastic Autoimmune KLHL11 Encephalitis
Divyanshu Dubey, MD, FAAN
02:48 PM - 03:00 PM Abstract 010 - Steroid-responsive Encephalopathy Associated with Autoimmune Thyroiditis: Clinical Presentation and Misdiagnosis
Cristina Valencia Sanchez, MD
Faculty Disclosures
Sarosh R. Irani, MD, PhD, FRCP, FEAN Dr. Irani has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for UCB, Immunovant, MedImmun, Roche, Janssen, Cerebral therapeutics, Biogen, Amgen, Argenex, Clarivate, IQVIA, BioHaven therapeutics, ADC therapeutics, Brain, CSL Behring, and ONO Pharma.. Dr. Irani has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for UCB. Dr. Irani has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. Dr. Irani has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Brain. Dr. Irani has received personal compensation in the range of $100,000-$499,999 for serving as an Expert Witness for LLPs. Dr. Irani has received intellectual property interests from a discovery or technology relating to health care. Dr. Irani has received intellectual property interests from a discovery or technology relating to health care. Dr. Irani has received intellectual property interests from a discovery or technology relating to health care.
Amanda C. Guidon, MD An immediate family member of Dr. Guidon has received personal compensation for serving as an employee of GE Healthcare. Dr. Guidon has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion. Dr. Guidon has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Momenta. Dr. Guidon has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Argenx. The institution of Dr. Guidon has received research support from MGFA. The institution of Dr. Guidon has received research support from Project Data Sphere. The institution of Dr. Guidon has received research support from MGNet. The institution of Dr. Guidon has received research support from MGNet. Dr. Guidon has received publishing royalties from a publication relating to health care.
Francesc R. Graus, MD Dr. Graus has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for MedLink. Dr. Graus has received intellectual property interests from a discovery or technology relating to health care.
Andrew McKeon, MD The institution of Dr. McKeon has received research support from National Institutes of Health. Dr. McKeon has received intellectual property interests from a discovery or technology relating to health care. Dr. McKeon has received intellectual property interests from a discovery or technology relating to health care. Dr. McKeon has received publishing royalties from a publication relating to health care.
Sean J. Pittock, MD, FAAN Dr. Pittock has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UCB. Dr. Pittock has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Arialys Therapeutics. The institution of Dr. Pittock has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion. Dr. Pittock has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Arialys. The institution of Dr. Pittock has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for UCB. The institution of Dr. Pittock has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche/Genentech. The institution of Dr. Pittock has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Alexion/AstraZeneka. The institution of Dr. Pittock has received research support from NIH. The institution of Dr. Pittock has received research support from Alexion/AstraZeneka. The institution of Dr. Pittock has received research support from F. Hoffman/LaRoche/Genentech. Dr. Pittock has received intellectual property interests from a discovery or technology relating to health care. Dr. Pittock has received intellectual property interests from a discovery or technology relating to health care. Dr. Pittock has received publishing royalties from a publication relating to health care.
Vanda Lennon, MD, PhD The institution of Dr. Lennon has received research support from NIH. Dr. Lennon has received intellectual property interests from a discovery or technology relating to health care.
Naomi Kanazawa Naomi Kanazawa has nothing to disclose.
Juntaro Kaneko Juntaro Kaneko has nothing to disclose.
Divyanshu Dubey, MD, FAAN The institution of Dr. Dubey has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Argenx. The institution of Dr. Dubey has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Arialys. The institution of Dr. Dubey has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UCB . Dr. Dubey has received research support from Department of Defense . Dr. Dubey has received research support from Department of Defense . Dr. Dubey has received research support from UCB. Dr. Dubey has received research support from David J. Tomassoni ALS Research Grant Program . Dr. Dubey has received intellectual property interests from a discovery or technology relating to health care. Dr. Dubey has received intellectual property interests from a discovery or technology relating to health care. Dr. Dubey has received intellectual property interests from a discovery or technology relating to health care. Dr. Dubey has received intellectual property interests from a discovery or technology relating to health care.
Joseph DeRisi, PhD Joseph DeRisi, PhD has received personal compensation for serving as an employee of Chan Zuckerberg Biohub. Joseph DeRisi, PhD has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Allen & Co. Joseph DeRisi, PhD has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Public Health Company, Inc. Joseph DeRisi, PhD has received personal compensation in the range of $0-$499 for serving as a Consultant for Delve Bio. Joseph DeRisi, PhD has received personal compensation in the range of $0-$499 for serving as a Consultant for VeriPhi Inc. The institution of Joseph DeRisi, PhD has received research support from Chan Zuckerberg Biohub. Joseph DeRisi, PhD has received intellectual property interests from a discovery or technology relating to health care.
No disclosure on file
Michelle Devine, MD The institution of an immediate family member of Dr. Devine has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UCB. The institution of an immediate family member of Dr. Devine has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Astellas. An immediate family member of Dr. Devine has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for UCB. An immediate family member of Dr. Devine has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for AAN. An immediate family member of Dr. Devine has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for AGRIMS. An immediate family member of Dr. Devine has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for Advances in Neurology. The institution of an immediate family member of Dr. Devine has received research support from Center of Individualized Medicine, Mayo Clinic.
James E. Eaton III, MD Dr. Eaton has received personal compensation in the range of $0-$499 for serving as a Consultant for Uniqure.
Kazutoshi Nishiyama, MD, PhD Kazutoshi Nishiyama, MD, PhD has nothing to disclose.
Nicholas L. Zalewski, MD Dr. Zalewski has nothing to disclose.
Josep O. Dalmau, MD, PhD, FAAN Dr. Dalmau has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Astellas Research Institute of America. Dr. Dalmau has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Janssen Research & Development . Dr. Dalmau has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for 好色先生. An immediate family member of Dr. Dalmau has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Springer Nature. The institution of Dr. Dalmau has received research support from Sage Therapeutics. The institution of Dr. Dalmau has received research support from Edmond J.Safra Foundation . The institution of Dr. Dalmau has received research support from La Caixa Foundation. The institution of Dr. Dalmau has received research support from Spanish Ministry of Health (ISCIII). The institution of Dr. Dalmau has received research support from Euroimmun, Inc. Dr. Dalmau has received intellectual property interests from a discovery or technology relating to health care. An immediate family member of Dr. Dalmau has received intellectual property interests from a discovery or technology relating to health care. Dr. Dalmau has received intellectual property interests from a discovery or technology relating to health care. An immediate family member of Dr. Dalmau has received intellectual property interests from a discovery or technology relating to health care. Dr. Dalmau has received publishing royalties from a publication relating to health care. Dr. Dalmau has received publishing royalties from a publication relating to health care. Dr. Dalmau has received publishing royalties from a publication relating to health care.
Eoin P. Flanagan, MBBCh, FAAN The institution of Dr. Flanagan has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion. Dr. Flanagan has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech. Dr. Flanagan has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Horizon Therapeutics. The institution of Dr. Flanagan has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. Dr. Flanagan has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Pharmacy times. The institution of Dr. Flanagan has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for UCB. The institution of Dr. Flanagan has received research support from Viela Bio. The institution of Dr. Flanagan has received research support from UCB. The institution of Dr. Flanagan has received research support from Roche. Dr. Flanagan has received publishing royalties from a publication relating to health care. Dr. Flanagan has a non-compensated relationship as a Member of medical Advisory Board with The MOG Project that is relevant to AAN interests or activities. Dr. Flanagan has a non-compensated relationship as a Editorial board member with Journal of The Neurologic Sciences that is relevant to AAN interests or activities. Dr. Flanagan has a non-compensated relationship as a Editorial board member with Neuroimmunology Reports that is relevant to AAN interests or activities. Dr. Flanagan has a non-compensated relationship as a Editorial Board Member with Neurology, Neuroimmunology Neuroinflammation (N2) Journal that is relevant to AAN interests or activities.
Bastien Joubert Bastien Joubert has nothing to disclose.
Anastasia Zekeridou, MD, PhD, FAAN The institution of Dr. Zekeridou has received research support from Roche/Genentech. Dr. Zekeridou has received intellectual property interests from a discovery or technology relating to health care. Dr. Zekeridou has received intellectual property interests from a discovery or technology relating to health care. Dr. Zekeridou has received intellectual property interests from a discovery or technology relating to health care. Dr. Zekeridou has received intellectual property interests from a discovery or technology relating to health care.
Jenny Linnoila, MD, PhD Dr. Linnoila has received research support from NIH/NINDS. Dr. Linnoila has received personal compensation in the range of $10,000-$49,999 for serving as a expert respondent on autoimmune encephalitis with U.S. government/DHHS/vaccine injury compensation program.
Scott D. Eggers, MD Dr. Eggers has received publishing royalties from a publication relating to health care.
Chad Hales, MD, PhD, FAAN The institution of Dr. Hales has received research support from BrightFocus foundation. The institution of Dr. Hales has received research support from NIH. The institution of Dr. Hales has received research support from State of Georgia. Dr. Hales has a non-compensated relationship as a committee member with AAN that is relevant to AAN interests or activities.
Jorge C. Kattah, MD, FAAN Dr. Kattah has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Bonezzi, Switzer , Poilitto and Hupp Legal Firm.
Kiran Thakur, MD, FAAN Dr. Thakur has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Delve Bio. The institution of Dr. Thakur has received research support from Center for Disease Control and Prevention.
Britany Klenofsky, MD Dr. Klenofsky has nothing to disclose.
Steven M. Wolf, MD Dr. Wolf has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Assertio. Dr. Wolf has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for LivaNova. Dr. Wolf has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Neurilis. Dr. Wolf has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for UCB. Dr. Wolf has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for MOnteris . Dr. Wolf has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Marinus . The institution of Dr. Wolf has received research support from Neuropace. The institution of Dr. Wolf has received research support from Eisai. The institution of Dr. Wolf has received research support from Aguestive. The institution of Dr. Wolf has received research support from Neurilis . The institution of Dr. Wolf has received research support from UCB. The institution of Dr. Wolf has received research support from SKLife . The institution of Dr. Wolf has received research support from Longboard . The institution of Dr. Wolf has received research support from Takeda. The institution of Dr. Wolf has received research support from biohaven. The institution of Dr. Wolf has received research support from Assertio. Dr. Wolf has received intellectual property interests from a discovery or technology relating to health care. Dr. Wolf has received publishing royalties from a publication relating to health care.
Eugenia Martinez-Hernandez, MD Dr. Martinez-Hernandez has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion. Dr. Martinez-Hernandez has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for UCB. Dr. Martinez-Hernandez has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Argenx. The institution of Dr. Martinez-Hernandez has received research support from Instituto de Salud Carlos III. Dr. Martinez-Hernandez has received personal compensation in the range of $500-$4,999 for serving as a support for attending meetings with Sanofi. Dr. Martinez-Hernandez has received personal compensation in the range of $500-$4,999 for serving as a support for attending meetings and speaker honoraria with UCB. Dr. Martinez-Hernandez has received personal compensation in the range of $500-$4,999 for serving as a speaker honoraria with Alexion. Dr. Martinez-Hernandez has received personal compensation in the range of $0-$499 for serving as a speaker honoraria with Terumo. Dr. Martinez-Hernandez has received personal compensation in the range of $500-$4,999 for serving as a support for attending meetings with Janssen. Dr. Martinez-Hernandez has received personal compensation in the range of $500-$4,999 for serving as a support for attending meetings with CSL Behring.
Jesús Ramírez-Bermúdez No disclosure on file
Zachary Grinspan, MD Dr. Grinspan has received personal compensation for serving as an employee of Weill Cornell Medicine. Dr. Grinspan has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alpha Insights. Dr. Grinspan has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biopharma LTD (South Korea). Dr. Grinspan has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Encoded Therapeutics. The institution of Dr. Grinspan has received research support from SLC6A1 Connect. The institution of Dr. Grinspan has received research support from STXBP1 Foundation. The institution of Dr. Grinspan has received research support from Clara Inspired. The institution of Dr. Grinspan has received research support from Amgen. The institution of Dr. Grinspan has received research support from NINDS. Dr. Grinspan has received intellectual property interests from a discovery or technology relating to health care.
Eiji Kitamura Eiji Kitamura has nothing to disclose.
Shelley S. Varnado, MD No disclosure on file
Takahiro Iizuka, MD The institution of Dr. Iizuka has received research support from EUROIMMUN Japan Co., Ltd.
Natasha Basma No disclosure on file
Cristina Valencia Sanchez, MD Dr. Valencia Sanchez has a non-compensated relationship as a member of the medical advisory board with The MOG Project that is relevant to AAN interests or activities.
Atsushi Kaneko No disclosure on file
Aaron L. Nelson, MD, FAAN Dr. Nelson has nothing to disclose.
Patricia E. McGoldrick, NP No disclosure on file
Elissa Yozawitz, MD Dr. Yozawitz has nothing to disclose.
Cynthia Arely Juarez Jaramillo No disclosure on file
James Fryer James Fryer has received intellectual property interests from a discovery or technology relating to health care.
Jessica A. Sagen, MA Ms. Sagen has nothing to disclose.
Mar Guasp, MD Dr. Guasp has nothing to disclose.
Joan Santamaria, MD Joan Santamaria, MD has nothing to disclose.
Dale C. Hesdorffer No disclosure on file
Thais Armangue, MD Dr. Armangue has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. The institution of Dr. Armangue has received research support from ISCIII(Spanish institute of health) -PI21/00316, Marato TV3, La Caixa Research Foundadion, Pablove Foundation (689368), Torrons Vicens Foundation (PFNR0144), 2021 Invest AEP.
Anusha Yeshokumar, MD Dr. Yeshokumar has nothing to disclose.
Parul Agarwal Parul Agarwal has nothing to disclose.
Virginia Casado Ruiz No disclosure on file
Nathalie Jette, MD, MSc, FRCPC, FAAN Dr. Jette has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for ILAE Epilepsia. The institution of Dr. Jette has received research support from NIH. The institution of Dr. Jette has received research support from AES.
Albert Saiz Albert Saiz has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi. Albert Saiz has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Horizon Therapeutics. Albert Saiz has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Merck. Albert Saiz has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Janseen. Albert Saiz has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Roche. Albert Saiz has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for novartis. Albert Saiz has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Biogen.
Nicole Luche No disclosure on file
Mary Claire Tuohy Ms. Tuohy has nothing to disclose.
Mariana Espinola-Nadurille No disclosure on file
Michael R. Wilson, MD, FAAN Dr. Wilson has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Delve Bio. Dr. Wilson has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Cambridge Medical Experts. Dr. Wilson has stock in Delve Bio. The institution of Dr. Wilson has received research support from Genentech / Roche. The institution of Dr. Wilson has received research support from NIH. The institution of Dr. Wilson has received research support from Novartis. The institution of Dr. Wilson has received research support from National Multiple Sclerosis Society. The institution of Dr. Wilson has received research support from Fanconi Anemia Research Foundation. The institution of Dr. Wilson has received research support from Department of Defense. The institution of Dr. Wilson has received research support from Chan Zuckerberg Initiative. Dr. Wilson has received intellectual property interests from a discovery or technology relating to health care. Dr. Wilson has received intellectual property interests from a discovery or technology relating to health care. Dr. Wilson has received personal compensation in the range of $10,000-$49,999 for serving as a Expert Witness with US Dept of Justice.
Shannon Hinson Shannon Hinson has received intellectual property interests from a discovery or technology relating to health care. Shannon Hinson has received intellectual property interests from a discovery or technology relating to health care.
John Cheville No disclosure on file
Benjamin Clarkson Benjamin Clarkson has received research support from Adimune. Benjamin Clarkson has received research support from Dominium Foundation.
Caleigh Mandel-Brehm, PhD The institution of Dr. Mandel-Brehm has received research support from NIH-NINDS K99/R00 grant. Dr. Mandel-Brehm has received intellectual property interests from a discovery or technology relating to health care.
Jiraporn Jitprapaikulsan, MD Dr. Jitprapaikulsan has nothing to disclose.
John R. Mills, MD, PhD The institution of Dr. Mills has received research support from Werfen Diagnostics. Dr. Mills has received intellectual property interests from a discovery or technology relating to health care.
Charles E. Kaufman, MD, FAAN No disclosure on file