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2008 Annual Meeting | Mitochondria in Diseases

Friday 04/18/08
01:00 PM - 05:00 PM Add To Calendar
This program will be presented both in-person and online
This program is not expected to be available in the meeting's On Demand product.
Integrated Neuroscience
Movement Disorders, Neuro-ophthalmology/Neuro-otology, Aging and Dementia, Child Neurology/Developmental Neurobiology, Muscle Disease/Neuromuscular Junction, Neurogenetics and Gene Therapy
No CME available
Event Timeline
01:00 PM - 02:00 PM Break
01:00 PM - 05:00 PM Abstract 001 - Mouse Model of Human Mitochondrial DNA Depletion Due to Mitochondrial Thymidine Kinase Deficiency
01:00 PM - 05:00 PM Abstract 001 - CoQ10 Deficiency: Clinical and Genetic Studies
01:00 PM - 05:00 PM Abstract 002 - Mitochondrial Network Disruption in Cultured Fibroblasts and Myotubes from Patients with a Novel OPA1 Gene Mutation
01:00 PM - 05:00 PM Abstract 002 - Deficiency of Cyclophilin D Protects A[beta]-Mediated Mitochondrial and Neuronal Stress in Alzheimer[apos]s Mouse Model
01:00 PM - 05:00 PM Abstract 003 - Abnormal Mitochondrial Function and Morphology in Fibroblasts of Patients with Early Onset Parkinson[apos]s Disease and Two Parkin Mutations
01:00 PM - 05:00 PM Abstract 003 - Unusual Clinical and Molecular Presentation of the A8344G Mutation in mtDNA tRNALys (The [ldquo]MERRF Mutation[rdquo])
01:00 PM - 05:00 PM Abstract 004 - The Presence of Lewy Body Pathology in Parkinsonism with Multiple Mitochondrial DNA Deletions; an Autopsy Case Report
01:00 PM - 05:00 PM Abstract 004 - Instability of the Mitochondrial Genome and Neurodegeneration
01:00 PM - 05:00 PM Abstract 005 - Prevention of mtDNA Depletion in Quiescent Skin Fibroblasts from a Patient with a Novel R225W Mutation in the TK2 Gene
01:00 PM - 05:00 PM Abstract 006 - [italic]OPA1[/italic] Mutations Induce Mitochondrial DNA Instability and Optic Atrophy Plus Phenotypes
01:00 PM - 05:00 PM Abstract 006 - Screening for [italic]POLG1[/italic] Mutations in a Southern Italian Population
01:00 PM - 05:00 PM Abstract 007 - Slowly Progressive Multisystem Disorder Associated with a G12276A Mutation in the mtDNA tRNALeu (CUN) Gene
01:00 PM - 05:00 PM Abstract 008 - Clinical Features in Five Children with Mutations in ND3, Another mtDNA [ldquo]Hotspot[rdquo]
01:00 PM - 05:00 PM Abstract 009 - Phase II Study of the Mitochondrial Antioxidant Mitoquinone for Parkinson[apos]s Disease
01:00 PM - 05:00 PM Abstract 010 - Clinical and Molecular Features in 27 Patients with Early-Onset Mitochondrial DNA Depletion Syndromes
01:00 PM - 05:00 PM Abstract 011 - Characterization of the Ethe1 Protein by Cellular and Animals Models: Towards an Understanding of Its Role in Ethylmalonic Encephalopathy
01:00 PM - 05:00 PM Abstract 012 - Respiratory Chain Dysfunction and Oxidative Stress Correlate with Severity of Primary CoQ10 Deficiency
Faculty Disclosures
M. F. Beal, MD No disclosure on file
Jeffery Vance, MD, PhD Dr. Vance has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for neurology genetics.
Janet L. Oblinger No disclosure on file
No disclosure on file
Zarife Sahenk, MD, PhD, FAAN Dr. Sahenk has nothing to disclose.
Dominique Bonneau No disclosure on file
Catarina Quinzii Hirano, MD No disclosure on file
Leonardo Salviati, MD No disclosure on file
Carlos A. Luciano, MD, FAAN Dr. Luciano has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Akcea Pharmaceuticals. Dr. Luciano has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Sanofi-Genzyme. Dr. Luciano has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for SIMED. Dr. Luciano has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Universal Insurance Co.. Dr. Luciano has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Pueblo Supermarket. The institution of Dr. Luciano has received research support from National Institutes of Health. The institution of Dr. Luciano has received research support from Catalyst Pharmaceuticals. Dr. Luciano has received personal compensation in the range of $100,000-$499,999 for serving as a Professor and Chair with University of Puerto Rico.
Rocco Liguori, MD Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Argenx. Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for HEALTHWARE GROUP s.r.l. . Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for ALEXION PHARMA ITALY s.r.l. . Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for SANOFI GENZYME CORPORATION . Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for ECM NETWORK s.r.l. . Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for ALEXION PHARMA ITALY s.r.l.. Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for PTS s.r.l. . Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for ALEXION PHARMA ITALY s.r.l.. Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for AIM EDUCATION s.r.l. . Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for MAYA IDEE SUD s.r.l. . Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for ISTITUTO SUPERIORE DI SANITA' . Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for QbGROUP s.r.l. . Dr. Liguori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for SYMPOSIUM s.r.l. . Dr. Liguori has received publishing royalties from a publication relating to health care.
Alessandra Baracca No disclosure on file
Luis Lopez No disclosure on file
Alessandro Filla, MD, FAAN No disclosure on file
Beatriz Dorado No disclosure on file
Valerio Carelli, MD, PhD Dr. Carelli has received personal compensation in the range of $0-$499 for serving as a Consultant for Chiesi Farmaceutici. Dr. Carelli has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Chiesi Farmaceutici.
Patrizia Amati-Bonneau No disclosure on file
Salvatore DiMauro, MD No disclosure on file
Corrado Angelini, MD, FAAN Dr. Angelini has nothing to disclose.
Giuliana Galassi, MD No disclosure on file
Nicholas W. Wood No disclosure on file
Massimo Zeviani, MD, PhD No disclosure on file
Chiara Criscuolo No disclosure on file
Barry Snow, MD, BchB No disclosure on file
Eduardo Bonilla, MD No disclosure on file
Antonella Spinazzola, MD No disclosure on file
Oliver E. Bandmann, MD, PhD, FAAN No disclosure on file
Marco Onofrj, MD Dr. Onofrj has nothing to disclose.
Jorida Coku No disclosure on file
Daita Kaneda, MD No disclosure on file
Michio Hirano, MD, FAAN Dr. Hirano has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UCB Biopharma SRL. Dr. Hirano has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Precision Biosciences. Dr. Hirano has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for UCB Biopharma SRL. Dr. Hirano has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Apollo Communication. Dr. Hirano has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Envision Communications. Dr. Hirano has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for 好色先生. Dr. Hirano has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Cure SMA. Dr. Hirano has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Muscular Dystrophy Association. The institution of Dr. Hirano has received research support from UCB. The institution of Dr. Hirano has received research support from Cyclerion. Dr. Hirano has received research support from Reneo Pharmaceuticals. The institution of Dr. Hirano has received research support from Astellas. Dr. Hirano has received intellectual property interests from a discovery or technology relating to health care. Dr. Hirano has received intellectual property interests from a discovery or technology relating to health care. Dr. Hirano has received personal compensation in the range of $0-$499 for serving as a Study Section Reviewer with NIH. Dr. Hirano has a non-compensated relationship as a Research Advisory Board member with Muscular Dystrophy Association that is relevant to AAN interests or activities. Dr. Hirano has a non-compensated relationship as a Scientific and Medical Advisory Board member with United Mitochondrial Disease Foundation that is relevant to AAN interests or activities. Dr. Hirano has a non-compensated relationship as a Scientific Advisory Board member with Barth Syndrome Foundation that is relevant to AAN interests or activities.
Subramaniam Sriram, MD Dr. Sriram has nothing to disclose.
Derek Narendra, MD The institution of Dr. Narendra has received research support from National Institutes of Health.
Christophe Verny No disclosure on file
Clifford J. Beall, PhD No disclosure on file
Maya Vila No disclosure on file
Ichizo Nishino, MD, PhD, FAAN The institution of Dr. Nishino has received research support from AMED.
Sara Shanske, PhD No disclosure on file
Pierre Labauge, MD Dr. Labauge has nothing to disclose.
K. Reed Clark, PhD No disclosure on file
Tomonobu Kato No disclosure on file
Marco Spinazzi, MD, PhD No disclosure on file
Chiara La Morgia, MD Dr. La Morgia has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Regulatory Pharmanet s.r.l. . Dr. La Morgia has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Santhera Pharmaceuticals. Dr. La Morgia has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Chiesi Farmaceutici s.p.a.. The institution of Dr. La Morgia has received research support from Italian Ministry of Health.
Fang Fang No disclosure on file
Heng Du No disclosure on file
Siddharama Pawate, MD The institution of Dr. Pawate has received research support from Genentech. The institution of Dr. Pawate has received research support from Biogen.
Alain Furby No disclosure on file
Valeria Tiranti No disclosure on file
Mahsa Mehrazin, MD No disclosure on file
Marc C. Patterson, MD, FRACP, FAAN Dr. Patterson has received personal compensation for serving as an employee of IntraBio. The institution of Dr. Patterson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Orphazyme /KemPharm/Zevra. Dr. Patterson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Azafaros. Dr. Patterson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for IntraBio. Dr. Patterson has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Sage. Dr. Patterson has stock in IntraBio. The institution of Dr. Patterson has received research support from Glycomine. The institution of Dr. Patterson has received research support from Orphazyme /KemPharm/Zevra. The institution of Dr. Patterson has received research support from Idorsia. The institution of Dr. Patterson has received research support from Shire-Takeda. Dr. Patterson has received publishing royalties from a publication relating to health care. Dr. Patterson has received publishing royalties from a publication relating to health care.
Michelle P. Lin, CRC Dr. Lin has nothing to disclose.
Claire F. Wardell No disclosure on file
Ali M. Alqahtani No disclosure on file
Nawaf A. Alqahtani No disclosure on file
Paul Gilbert, PhD Dr. Gilbert has nothing to disclose.
Andrew Herndon No disclosure on file
Sarah A. Morrow, MD, MSC, FRCPC, FAAN Dr. Morrow has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for BIogen Idec. Dr. Morrow has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for EMD Serono/Merck. Dr. Morrow has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Celgene. Dr. Morrow has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Morrow has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. Dr. Morrow has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for SanofiGenzyme. Dr. Morrow has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Biogen Idec. Dr. Morrow has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Novartis. Dr. Morrow has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Roche. The institution of Dr. Morrow has received research support from Celgene.
Santiago M. Pagano Ajolfi, Sr., MD No disclosure on file
Mikio Shoji, MD No disclosure on file
Ameera Haque No disclosure on file
Stephen J. Howell, BS, EMT-B Mr. Howell has nothing to disclose.
Takumi Nakamura, MD No disclosure on file
Ryan P. Renn No disclosure on file