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2011 Annual Meeting | Advances in the Genetics of Movement Disorders

Monday 04/11/11
02:00 PM - 06:00 PM Add To Calendar
This program will be presented both in-person and online
This program is not expected to be available in the meeting's On Demand product.
Integrated Neuroscience
Movement Disorders, Aging and Dementia, Autonomic Disorders, Neurogenetics and Gene Therapy
No CME available
Event Timeline
02:00 PM - 06:00 PM Abstract 001 - The [italic]LRRK2[/italic] G2019S Mutation Predisposes Parkinson[apos]s Disease Patients to Cancer
02:00 PM - 06:00 PM Abstract 001 - A Novel Therapeutic Approach for SCA6: Splice-Isoform-Specific RNA Interference
02:00 PM - 06:00 PM Abstract 002 - Mitochondrial Genome Integrity in Parkinson[apos]s Disease Patients with [italic]PINK1[/italic] Mutations and Controls
02:00 PM - 06:00 PM Abstract 002 - Transcriptome Profiling of Blood Mononuclear Cells from SCA2 Patients According to Cerebellar or Parkinsonian Phenotypes
02:00 PM - 06:00 PM Abstract 003 - Multivariate Features Associated with Presence of [ldquo]Severe[rdquo] Mutations in the GBA Gene in a Cohort of Asymptomatic First Degree Relatives of Patient with Parkinson[apos]s Disease
02:00 PM - 06:00 PM Abstract 004 - Understanding Molecular Mechanisms in Mitochondria Underlying Lrrk2-Related Parkinson[apos]s Disease in the Mouse Model
02:00 PM - 06:00 PM Abstract 004 - Relative Risk for Melanoma and Lung Cancer in the Parkinson [apos]s Disease Population and Their Relatives Using the Utah Population Data Base
02:00 PM - 06:00 PM Abstract 005 - Common Variants in PARK Loci and Related Genes and Parkinson[apos]s Disease
02:00 PM - 06:00 PM Abstract 005 - Pathway Analysis for Parkinson Disease: An Integrative Systems Biology Aproach
02:00 PM - 06:00 PM Abstract 006 - Autonomic Nervous System Study in Patients with SNCA (E46K) and LRRK2 (R1441G and G2019S) Gene Mutations
02:00 PM - 06:00 PM Abstract 007 - Neuroprotective Potential of DJ-1: Related Peptides Exert Protection in Models of Parkinson[apos]s Disease
02:00 PM - 06:00 PM Abstract 008 - Clinical Characteristics of Neurodegenerative Disease in Carriers of the [italic]MAPT[/italic] A152T Variant
02:00 PM - 06:00 PM Abstract 009 - Homozygous [italic]THAP1[/italic] Mutations as Cause of Early-Onset Generalized Dystonia
02:00 PM - 06:00 PM Abstract 010 - Genomic Determinants of Motor and Cognitive Outcomes in Parkinson[apos]s Disease
02:00 PM - 06:00 PM Abstract 011 - Association of Lingo2 Genetic Variants with Essential Tremor and Parkinson[apos]s Disease
02:00 PM - 06:00 PM Abstract 012 - Analysis of Leucine Rich Repeat and Ig Domain Containing 1 Variants in Essential Tremor
02:00 PM - 06:00 PM Abstract 013 - Patterns of Neurological Manifestation in Woodhouse-Sakati Syndrome
02:00 PM - 06:00 PM Abstract 014 - Visualization of siRNA Complexed to RISC Machinery: Demonstrating Intercellular siRNA Transfer by Directly Imaging Activity
02:00 PM - 06:00 PM Abstract 015 - Late Onset Episodic Ataxia: A Case Series
Faculty Disclosures
Anthony E. Lang, MD, FAAN Dr. Lang has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for AbbVie, Amylyx, Aprinoia, Biogen, BioAdvance, Biohaven, BioVie, BlueRock, BMS, Denali, Janssen, Lilly, Pharma 2B, Sun Pharma, and UCB. Dr. Lang has received personal compensation in the range of $50,000-$99,999 for serving as an Expert Witness for medicolegal cases related to paraquat. The institution of Dr. Lang has received research support from AbbVie. Dr. Lang has received intellectual property interests from a discovery or technology relating to health care. Dr. Lang has received publishing royalties from a publication relating to health care.
Hidehiro Mizusawa, MD, PhD No disclosure on file
Demetrius M. Maraganore, MD, FAAN The institution of Dr. Maraganore has received research support from Agency for Healthcare Research and Quality. The institution of Dr. Maraganore has received research support from Florida Department of Health.
Sun Ju Chung, MD, PhD, FAAN Dr. Chung has nothing to disclose.
No disclosure on file
Matthew Farrer, MD No disclosure on file
Nir Giladi, MD, FAAN Dr. Giladi has received personal compensation in the range of $0-$499 for serving as a Consultant for Sionara. Dr. Giladi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for NeuroDerm. Dr. Giladi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Pharma2B. Dr. Giladi has stock in Vibrant. Dr. Giladi has stock in Lysosomal Therapeutics . The institution of Dr. Giladi has received research support from The Michael J Fox Foundation. The institution of Dr. Giladi has received research support from The National Parkinson Foundation. The institution of Dr. Giladi has received research support from The European Union . The institution of Dr. Giladi has received research support from The Israel Science Foundation. The institution of Dr. Giladi has received research support from Biogen . The institution of Dr. Giladi has received research support from Ionis. The institution of Dr. Giladi has received research support from Sieratzki Family Foundation . The institution of Dr. Giladi has received research support from The Aufzien Academic Center in Tel-Aviv University.
Sharon Hassin, MD Dr. Hassin has received personal compensation in the range of $500-$4,999 for serving as a Consultant for ABBVIE. Dr. Hassin has received personal compensation in the range of $500-$4,999 for serving as a Consultant for MEDISON. Dr. Hassin has received personal compensation in the range of $500-$4,999 for serving as a Consultant for TEVA. Dr. Hassin has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for NEURODERM. Dr. Hassin has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for TEVA. Dr. Hassin has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for ABBVIE. Dr. Hassin has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for TEVA.
Guney Bademci No disclosure on file
Margaret A. Pericak-Vance, PhD Dr. Pericak-Vance has nothing to disclose.
Eldad Melamed, MD No disclosure on file
Oren S. Cohen, MD No disclosure on file
William K. Scott, MD No disclosure on file
Aleksandar Rakovic No disclosure on file
Saeed A. Bohlega, MD No disclosure on file
Jeffery Vance, MD, PhD Dr. Vance has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for neurology genetics.
Nirit Lev, MD No disclosure on file
David Devos The institution of Mr. Devos has received research support from Alterity.
Christine Klein, MD Dr. Klein has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Centogene and Retromer Therapeutics. Dr. Klein has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Mov Disord, Ann Neurol, Science Adv. The institution of Dr. Klein has received research support from Centogene. Dr. Klein has received publishing royalties from a publication relating to health care.
Jarlath French-Mullen No disclosure on file
Abdulaziz M. Al-Semari, MD No disclosure on file
Maria Luisa Gorno Tempini, MD, PhD The institution of Dr. Gorno Tempini has received research support from the NIH.
Gary W. Beecham, PhD The institution of Dr. Beecham has received research support from NIH. The institution of an immediate family member of Dr. Beecham has received research support from NIH.
Michael D. Geschwind, MD, PhD, FAAN Dr. Geschwind has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Brainstorm Cell Therapeutics, Inc.. Dr. Geschwind has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Walter Grubb. Dr. Geschwind has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Gerson Lehrman Group. Dr. Geschwind has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Reata Pharmaceuticals, Inc..
J. E. Ahlskog, MD, PhD Dr. Ahlskog has received publishing royalties from a publication relating to health care.
William W. Seeley, MD Dr. Seeley has received personal compensation in the range of $500-$4,999 for serving as a Consultant for GLG Council. Dr. Seeley has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Guidepoint Global Consulting. Dr. Seeley has received personal compensation in the range of $500-$4,999 for serving as a Consultant for BridgeBio. Dr. Seeley has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Biogen. Dr. Seeley has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Lyterian Therapeutics. The institution of Dr. Seeley has received research support from NIH. The institution of Dr. Seeley has received research support from Rainwater Charitable Foundation. The institution of Dr. Seeley has received research support from Bluefield Project to Cure FTD. The institution of Dr. Seeley has received research support from Chan-Zuckerberg Initiative.
Kailash P. Bhatia, MD, FAAN Dr. Bhatia has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Ipsen. Dr. Bhatia has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for MDS . Dr. Bhatia has received publishing royalties from a publication relating to health care.
Norbert Bruggemann, MD No disclosure on file
Gil D. Rabinovici, MD, FAAN Dr. Rabinovici has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Eli Lilly. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alector. Dr. Rabinovici has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Merck. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genentech. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novo Norodisk. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Consultant for C2N. Dr. Rabinovici has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Johnson & Joihnson. Dr. Rabinovici has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Peerview. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Medscape. Dr. Rabinovici has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for JAMA Neurology. Dr. Rabinovici has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for JAMA. The institution of Dr. Rabinovici has received research support from NIH. The institution of Dr. Rabinovici has received research support from American College of Radiology. The institution of Dr. Rabinovici has received research support from Alzheimer's Association. The institution of Dr. Rabinovici has received research support from Rainwater Charitable Foundation. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Topic Chair, Course Director and teacher with AAN. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Grant reviewer with NIH. Dr. Rabinovici has received personal compensation in the range of $500-$4,999 for serving as a Invited speaker with ANA.
Juan Carlos Gomez Esteban, MD Dr. Gomez Esteban has nothing to disclose.
Giovanni Coppola, MD Dr. Coppola has received personal compensation for serving as an employee of Regeneron. Dr. Coppola has received stock or an ownership interest from Regeneron.
Suzee Lee, MD Dr. Lee has nothing to disclose.
Adam L. Boxer, MD, PhD An immediate family member of Dr. Boxer has received personal compensation for serving as an employee of Kaiser Permanente. Dr. Boxer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Ono. Dr. Boxer has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Oscotec. Dr. Boxer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly. Dr. Boxer has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Arrowhead. Dr. Boxer has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Neurocrine Biosciences. Dr. Boxer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Switch. Dr. Boxer has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Arvinas. Dr. Boxer has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Alector. Dr. Boxer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Merck. Dr. Boxer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alexion. Dr. Boxer has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Transposon. Dr. Boxer has stock in Alector. Dr. Boxer has stock in Arvinas. Dr. Boxer has stock in Neurovanda. The institution of Dr. Boxer has received research support from Biogen. The institution of Dr. Boxer has received research support from Eisai. The institution of Dr. Boxer has received research support from Regeneron. The institution of Dr. Boxer has received research support from NIH. The institution of Dr. Boxer has received research support from Bluefield Project. Dr. Boxer has received research support from Rainwater Charitable Foundation.
Ines Escalza, MD No disclosure on file
Susanne A. Schneider, MD, PhD No disclosure on file
Elena Lezcano No disclosure on file
Joel Kramer, PhD The institution of Dr. Kramer has received research support from tau consortium. Dr. Kramer has received publishing royalties from a publication relating to health care.
Bruce L. Miller, MD, FAAN Dr. Miller has nothing to disclose.
W. C. LaFrance, Jr., MD, MPH, FAAN Dr. LaFrance has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for medico-legal work.. The institution of Dr. LaFrance has received research support from Department of Defense. Dr. LaFrance has received publishing royalties from a publication relating to health care. Dr. LaFrance has received publishing royalties from a publication relating to health care.
Daniel H. Geschwind, MD, PhD Dr. Geschwind has received personal compensation in the range of $100,000-$499,999 for serving as a Consultant for Ovid Therapeutics, Inc.. Dr. Geschwind has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for AcuraStem, Inc.. Dr. Geschwind has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Axial Biotherapeutics, Inc.. Dr. Geschwind has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Falcon Computing. Dr. Geschwind has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier-Biological Psychiatry. Dr. Geschwind has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for NYAS. Dr. Geschwind has received personal compensation in the range of $50,000-$99,999 for serving as an Expert Witness for Covington& Burling LLP. Dr. Geschwind has stock in none related to talk. The institution of Dr. Geschwind has received research support from CurePSP. The institution of Dr. Geschwind has received research support from NINDS. The institution of Dr. Geschwind has received research support from Rainwater Charitable Foundation. The institution of Dr. Geschwind has received research support from NIMH. The institution of Dr. Geschwind has received research support from NINDS. The institution of Dr. Geschwind has received research support from NIH. The institution of Dr. Geschwind has received research support from The Simons Foundation. The institution of Dr. Geschwind has received research support from NIH/NIMH. The institution of Dr. Geschwind has received research support from Adelson Medical Research Foundation. The institution of Dr. Geschwind has received research support from NINDS. The institution of Dr. Geschwind has received research support from NIMH. The institution of Dr. Geschwind has received research support from NINDS/NIA. The institution of Dr. Geschwind has received research support from NIH/NIMH. The institution of Dr. Geschwind has received research support from Adelson Medical Research Foundation. The institution of Dr. Geschwind has received research support from NIH/NINDS. The institution of Dr. Geschwind has received research support from NIH/NIMH. The institution of Dr. Geschwind has received research support from NIH/NIMH. The institution of Dr. Geschwind has received research support from Adelson Medical Research Foundation. The institution of Dr. Geschwind has received research support from U of Virginia and NIH/NIMH. The institution of Dr. Geschwind has received research support from NIH. The institution of Dr. Geschwind has received research support from NIH/NHGRI. The institution of Dr. Geschwind has received research support from NIH/NIMH. Dr. Geschwind has received intellectual property interests from a discovery or technology relating to health care. Dr. Geschwind has received intellectual property interests from a discovery or technology relating to health care. Dr. Geschwind has received intellectual property interests from a discovery or technology relating to health care. Dr. Geschwind has received intellectual property interests from a discovery or technology relating to health care.
Rosa Rademakers, PhD Rosa Rademakers, PhD has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Mayo Clinic. Rosa Rademakers, PhD has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Arkuda Therapeutics. Rosa Rademakers, PhD has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Alzheimer Fondation. Rosa Rademakers, PhD has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Kisick Family Foundation (FTD grant program). The institution of Rosa Rademakers, PhD has received research support from NIH. The institution of Rosa Rademakers, PhD has received research support from DOD. The institution of Rosa Rademakers, PhD has received research support from Flanders Institute for Biotechnology (VIB). The institution of Rosa Rademakers, PhD has received research support from Flanders Funds for Scientific Research.
Bing-Wen Soong, MD, PhD, FAAN No disclosure on file
Rivka Inzelberg, MD No disclosure on file
Alain Destee, MD, PhD No disclosure on file
Lilach Ephraty No disclosure on file
Wei-Ling Tsou No disclosure on file
Christopher Gomez, MD, PhD Dr. Gomez has nothing to disclose.
Yoon-Hee Cha, MD, FAAN The institution of Dr. Cha has received research support from Mal de Debarquement Balance Disorders Foundation. Dr. Cha has received research support from University of Minnesota. Dr. Cha has received research support from MNDrive.
Hong Jiang, MD, PhD The institution of Dr. Jiang has received research support from Florida Health. The institution of Dr. Jiang has received research support from NINDS RO1.
Judith Aharon-Peretz, MD Dr. Aharon-Peretz has nothing to disclose.
Clemence Simonin, MD No disclosure on file
Robert W. Baloh, MD, FAAN No disclosure on file
Alexandre Kreisler No disclosure on file
Ruth Djaldetti, MD No disclosure on file
Henry L. Paulson, MD, PhD, FAAN Dr. Paulson has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Exicure. The institution of Dr. Paulson has received research support from National Institutes of Health. Dr. Paulson has a non-compensated relationship as a Member, Nominating committee with American Neurological Association that is relevant to AAN interests or activities.
Joanna C. Jen, MD, PhD Dr. Jen has nothing to disclose.
Luc Defebvre No disclosure on file
Eugenie Mutez, MD, PhD No disclosure on file
Ilana Z. Schlesinger, MD No disclosure on file
Iscia Lopes-Cendes, MD, PhD No disclosure on file
Brian S. Katz, MD No disclosure on file
Wang L. Au, MBBS, MRCP, (UK) No disclosure on file
Stefan M. Pulst, MD, FAAN Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for venrock. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Arrowhead. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Leverna. Dr. Pulst has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AAN. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Leninthal LLC. The institution of Dr. Pulst has received research support from NINDS. Dr. Pulst has received intellectual property interests from a discovery or technology relating to health care.
Louis C. Tan, MRCP No disclosure on file
Anas N. Harun, MD No disclosure on file
Lara K. Ronan, MD, FAAN No disclosure on file
Vishunmurthy S. Hedna, MD No disclosure on file
Jan Nolta, PhD No disclosure on file
Scott E. Olson, MD No disclosure on file
Seth Kareus, MD, FAAN No disclosure on file
Norazieda Yassin, MD No disclosure on file
Anna Karydas No disclosure on file
Beatriz Tijero Merino, MD No disclosure on file
Israel Steiner, MD No disclosure on file
Koldo Berganzo Corrales, MD No disclosure on file
Kareh Shafiee, MD No disclosure on file
Juan J. Zarranz, MD No disclosure on file
Deborah C. Mash, PhD No disclosure on file
John B. Williamson No disclosure on file
Sharyl R. Martini, MD, PhD Dr. Martini has nothing to disclose.
Anne K. Grunewald, PhD No disclosure on file
Daniel Miller, MD Dr. Miller has nothing to disclose.
Abdulrahman Alwaki, MD Dr. Alwaki has nothing to disclose.
Christopher M. Goshgarian, MD Dr. Goshgarian has nothing to disclose.
Carolyn Mehaffey, MD No disclosure on file
Alexander M. Lopez No disclosure on file
Rachel Nolan Ms. Nolan has nothing to disclose.
Palak S. Patel, MD Dr. Patel has nothing to disclose.
Marc Rosenblum No disclosure on file
Sanjay Anandaram, MD Dr. Anandaram has nothing to disclose.
Jason Huse No disclosure on file