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2014 Annual Meeting | Proteinopathy in Neurodegenerative Disease

Friday 05/02/14
08:00 AM - 12:00 PM Add To Calendar
This program will be presented both in-person and online
This program is not expected to be available in the meeting's On Demand product.
Integrated Neuroscience
Carol F. Lippa, MD, David G. Munoz, MD
Aging, Dementia, and Behavioral Neurology
Participant should become familiar with how the different aberrant aggregates of specific proteins is leading to protein-based biomarkers for diagnosis of neurodegenerative disease and to the development of disease modifying treatments based on pathogenesis. They should be able to answer patient/caregiver questions regarding the potential infectivity of these diseases.
No CME available
Subspecialty in Focus
Trainee, General Neurologist, Specialist Neurologist
Didactic, Audience Participation
Event Timeline
08:00 AM - 08:15 AM Neurodegenerative Disease: Past, Present, and Future
David G. Munoz, MD
08:00 AM - 12:00 PM Abstract 001 - An Abeta Oligomer Receptor Antagonist and Antibodies to Specific Target Receptor Epitopes Displace Abeta Oligomers in Alzheimer's Patient Brain Tissue Sections
08:00 AM - 12:00 PM Abstract 001 - RER1: A Novel Regulator of Alpha-Synuclein
Nikolaus McFarland, MD, PhD, FAAN
08:00 AM - 12:00 PM Abstract 002 - Imaging tau pathology in vivo in FTLD: initial experience with [18F] T807 PET
Bradford Dickerson, MD, FAAN
08:00 AM - 12:00 PM Abstract 002 - HuR is Essential for TDP-43 Expression through Posttranscriptional Mechanisms: Implications for Motor Neuron Toxicity and ALS
Liang Lu, MD, FAAN
08:00 AM - 12:00 PM Abstract 003 - A CSF Signature of Frontotemporal Lobar Degeneration with C9orf72 repeat expansions
William T. Hu, MD, PhD, FAAN
08:00 AM - 12:00 PM Abstract 003 - ?-synuclein in red blood cells is a potential diagnostic biomarker for Parkinson's disease
Rodolfo Savica, MD, PhD, FAAN
08:00 AM - 12:00 PM Abstract 004 - Progressive Supranuclear Palsy (PSP): Diagnosis through Skin Biopsy
Ildefonso Rodriguez-Leyva, MD, PhD, FAAN
08:00 AM - 12:00 PM Abstract 004 - Isradipine Rescues Alpha-synuclein Toxicity in a Zebrafish Model of Parkinson's Disease by Upregulating Autophagy
Mark C. Stahl, MD, PhD
08:00 AM - 12:00 PM Abstract 005 - GGGGCC repeat expansion of C9ORF72 is toxic via sequestration of RNA binding proteins and consequent disruption of RNA splicing
Johnathan Cooper-Knock, MD
08:00 AM - 12:00 PM Abstract 005 - Spinocerebellar Ataxias with Hypogonadism: Unraveling a Novel Group of Inherited Neurometabolic Disorders
Charles M. Lourenco, MD, PhD
08:00 AM - 12:00 PM Abstract 006 - Complement Factor H is a Biomarker for Mild Cognitive Impairment Not Due to Alzheimer's Disease
Trung P. Nguyen, MD
08:00 AM - 12:00 PM Abstract 007 - Cytoplasmic Redistribution of Mutant TDP-43 in a BAC Based Mouse Model of Amyotrophic Lateral Sclerosis
Kevin Talbot, MD, PhD
08:00 AM - 12:00 PM Abstract 008 - Coenzyme Q10, Statin, and Spinocerebellar Ataxias
Sheng-Han Kuo, MD, FAAN
08:00 AM - 12:00 PM Abstract 010 - PACAP Deficit in Alzheimer's Disease and Protection Against Beta-Amyloid Toxicity
Peng Cheng Han, PhD
08:15 AM - 08:45 AM Bioenergetic Consequences of Protein Misfolding in Neurodegenerative Diseases
M. F. Beal, MD
08:45 AM - 09:15 AM Molecular Correlates of Alzheimer Progression
Bradley T. Hyman, MD, PhD
09:15 AM - 09:45 AM Alpha-Synuclein Associated Mechanisms of Neuronal Injury: The Mitochondrial Link
J. T. Greenamyre, MD, PhD
09:45 AM - 10:15 AM Prion-like Diseases: The Future is Unfolding
Neil Cashman, MD
10:15 AM - 10:30 AM Panel Discussion
10:30 AM - 11:30 AM Poster Rounds
11:30 AM - 12:00 PM Data Blitz
Faculty Disclosures
Carol F. Lippa, MD Dr. Lippa has nothing to disclose.
David G. Munoz, MD No disclosure on file
M. F. Beal, MD No disclosure on file
Bradley T. Hyman, MD, PhD An immediate family member of Dr. Hyman has received personal compensation for serving as an employee of novartis. Dr. Hyman has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for dewpoint. Dr. Hyman has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for abbvie. Dr. Hyman has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Arvinas. Dr. Hyman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for avrobio. Dr. Hyman has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Biogen. Dr. Hyman has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Dept of Justice. Dr. Hyman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Cell Signalling. Dr. Hyman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sangamo. Dr. Hyman has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for sanofi. Dr. Hyman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for vigil. Dr. Hyman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for voyager. Dr. Hyman has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for biogen. Dr. Hyman has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for dept of justice. Dr. Hyman has stock in dewpoint. The institution of Dr. Hyman has received research support from nih. The institution of Dr. Hyman has received research support from JPB. The institution of Dr. Hyman has received research support from Cure Alz Fund. The institution of Dr. Hyman has received research support from Tau consortium. The institution of Dr. Hyman has received research support from abbvie. The institution of Dr. Hyman has received research support from BMS.
J. T. Greenamyre, MD, PhD The institution of Dr. Greenamyre has received research support from NIH. The institution of Dr. Greenamyre has received research support from Michael J Fox Foundation. The institution of Dr. Greenamyre has received research support from Calico Life Sciences. The institution of Dr. Greenamyre has received research support from Acurex.
Neil Cashman, MD Dr. Cashman has received personal compensation for serving as an employee of ProMIS Neurosciences. Dr. Cashman has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for IONIS. Dr. Cashman has stock in ProMIS Neurosciences. The institution of Dr. Cashman has received research support from ProMIS Neurosciences. Dr. Cashman has received intellectual property interests from a discovery or technology relating to health care.
Bradley F. Boeve, MD, FAAN Dr. Boeve has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Rainwater Charitable Foundation. The institution of Dr. Boeve has received research support from Alector. The institution of Dr. Boeve has received research support from EIP Pharma. The institution of Dr. Boeve has received research support from Transposon. The institution of Dr. Boeve has received research support from Cognition Therapeutics. Dr. Boeve has received publishing royalties from a publication relating to health care.
Stephan Zuchner, MD, FAAN Dr. Zuchner has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Applied Therapeutics. The institution of Dr. Zuchner has received research support from Muscular Dystrophy Association. The institution of Dr. Zuchner has received research support from CMT Association. Dr. Zuchner has received intellectual property interests from a discovery or technology relating to health care.
Nikolaus McFarland, MD, PhD, FAAN Dr. McFarland has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sutter Health. Dr. McFarland has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for ONO Pharmaceuticals. Dr. McFarland has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Ferrer. The institution of Dr. McFarland has received research support from NIH, Michael J. Fox Foundation, Huntington Disease Society for America, CurePSP, and Mission MSA.. Dr. McFarland has received publishing royalties from a publication relating to health care.
Thomas Beach Thomas Beach has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Vivid Genomics. Thomas Beach has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Roche Diagnostics. The institution of Thomas Beach has received research support from National Institutes of Health. The institution of Thomas Beach has received research support from Michael J Fox Foundation . The institution of Thomas Beach has received research support from State of Arizona.
Andrea Bozoki, MD, FAAN Dr. Bozoki has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Creative Biopeptides. Dr. Bozoki has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Cognition Therapeutics. The institution of Dr. Bozoki has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for AviadoBio. The institution of Dr. Bozoki has received research support from Cognition Therapeutics. The institution of Dr. Bozoki has received research support from EIP Pharma. The institution of Dr. Bozoki has received research support from Transposon Therapeutics. The institution of Dr. Bozoki has received research support from Alector .
Bradford Dickerson, MD, FAAN Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Acadia. Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Arkuda. Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai. Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Lantheus. Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Lilly. Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Merck. Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novo Nordisk. Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Merck. Dr. Dickerson has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Arkuda. Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Acadia. Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Lilly. Dr. Dickerson has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier. Dr. Dickerson has received publishing royalties from a publication relating to health care. Dr. Dickerson has received publishing royalties from a publication relating to health care.
Daniel Hoch, MD, PhD, FAAN No disclosure on file
Martha Morrell, MD, FAAN Dr. Morrell has received personal compensation for serving as an employee of NeuroPace. Dr. Morrell has stock in NeuroPace. The institution of Dr. Morrell has received research support from National Institutes of Health.
Kevin Talbot, MD, PhD No disclosure on file
Keith A. Johnson, MD Dr. Johnson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Johnson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Janssen. An immediate family member of Dr. Johnson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for AC Immune. An immediate family member of Dr. Johnson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Shionogi. An immediate family member of Dr. Johnson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Prothena. An immediate family member of Dr. Johnson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for NervGen. An immediate family member of Dr. Johnson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Oligomerix. Dr. Johnson has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for AC Immune. The institution of Dr. Johnson has received research support from National Institute on Aging. The institution of an immediate family member of Dr. Johnson has received research support from Alzheimer's Association. The institution of an immediate family member of Dr. Johnson has received research support from Eli Lilly and Co. The institution of Dr. Johnson has received research support from Eisai. The institution of an immediate family member of Dr. Johnson has received research support from Eisai.
No disclosure on file
Jeff M. Bronstein, MD, PhD Dr. Bronstein has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Ultragenyx. The institution of Dr. Bronstein has received research support from NIH. The institution of Dr. Bronstein has received research support from Levine Foundation.
Paolo Ragonese No disclosure on file
William T. Hu, MD, PhD, FAAN Dr. Hu has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Fujirebio. Dr. Hu has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Beckman Coulter. Dr. Hu has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Apellis Pharmaceuticals. The institution of Dr. Hu has received research support from NIA. The institution of Dr. Hu has received research support from TMCity Foundation. The institution of Dr. Hu has received research support from Atlanta Family Foundation. The institution of Dr. Hu has received research support from Fujirebio Diagnostics.
James J. Lah, MD, PhD Dr. Lah has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche Diagnostics. The institution of Dr. Lah has received research support from Roche.
Allan I. Levey, MD, PhD Dr. Levey has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Genuv. Dr. Levey has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Cognito Therapeutics. Dr. Levey has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Levey has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Karuna Pharmaceuticals. Dr. Levey has received stock or an ownership interest from NextSense. The institution of Dr. Levey has received research support from NIH. The institution of Dr. Levey has received research support from Biogen. The institution of Dr. Levey has received research support from Esai. The institution of Dr. Levey has received research support from AAN. The institution of Dr. Levey has received research support from State of Georgia. The institution of Dr. Levey has received research support from Novartis. The institution of Dr. Levey has received research support from Genentech. Dr. Levey has received intellectual property interests from a discovery or technology relating to health care. Dr. Levey has received personal compensation in the range of $500-$4,999 for serving as a NAPA Avisory Committee Co-Chair with US Dept of Health and Human Services.
Jonathan D. Glass, MD Dr. Glass has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Glass has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Apic Bio. Dr. Glass has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for CIRM. Dr. Glass has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Bryan Cave Leighton Paisner. The institution of Dr. Glass has received research support from NIH. The institution of Dr. Glass has received research support from ALS Assoiciation. The institution of Dr. Glass has received research support from Muscular Dystrophy Assoication.
Ana L. Calderon-Garciduenas, MD, PhD No disclosure on file
Stefan M. Pulst, MD, FAAN Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for venrock. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Arrowhead. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Leverna. Dr. Pulst has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AAN. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Leninthal LLC. The institution of Dr. Pulst has received research support from NINDS. Dr. Pulst has received intellectual property interests from a discovery or technology relating to health care.
Peter H. King, MD The institution of Dr. King has received research support from Department of Veterans Affairs. The institution of Dr. King has received research support from NIH.
Jeremy D. Schmahmann, MD, FAAN Dr. Schmahmann has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Biohaven. The institution of Dr. Schmahmann has received research support from National Ataxia Foundation. The institution of Dr. Schmahmann has received research support from Biohaven. Dr. Schmahmann has received intellectual property interests from a discovery or technology relating to health care. Dr. Schmahmann has received publishing royalties from a publication relating to health care. Dr. Schmahmann has received publishing royalties from a publication relating to health care. Dr. Schmahmann has received publishing royalties from a publication relating to health care.
Michael D. Geschwind, MD, PhD, FAAN Dr. Geschwind has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Brainstorm Cell Therapeutics, Inc.. Dr. Geschwind has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Walter Grubb. Dr. Geschwind has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Gerson Lehrman Group. Dr. Geschwind has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Reata Pharmaceuticals, Inc..
Henry L. Paulson, MD, PhD, FAAN Dr. Paulson has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Exicure. The institution of Dr. Paulson has received research support from National Institutes of Health. Dr. Paulson has a non-compensated relationship as a Member, Nominating committee with American Neurological Association that is relevant to AAN interests or activities.
Pamela J. Shaw, MD, FRCP, FAAN No disclosure on file
Sarah H. Ying, MD Dr. Ying has nothing to disclose.
Eric M. Reiman, MD Dr. Reiman has received personal compensation in the range of $50,000-$99,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Denali, Green Valley, Zinfandel, and Takeda. Dr. Reiman has received stock or an ownership interest from Alkahest, Alzheon, Aural Analytics, Denali, and United Neuroscience.. Dr. Reiman has received intellectual property interests from a discovery or technology relating to health care. Dr. Reiman has received personal compensation in the range of $500-$4,999 for serving as a Member, National Advisory Council on Aging (NACA) with NIA.
Charles M. Lourenco, MD, PhD No disclosure on file
Veronica M. Mier No disclosure on file
Trung P. Nguyen, MD The institution of Dr. Nguyen has received research support from National Institute on Aging. The institution of Dr. Nguyen has received research support from Texas Alzheimer's Research and Care Consortium. The institution of Dr. Nguyen has received research support from Biogen.
Vikram Shakkottai, MD, PhD The institution of Dr. Shakkottai has received research support from National Institutes of Health. Dr. Shakkottai has received publishing royalties from a publication relating to health care.
Marianne De Visser, MD, PhD Dr. De Visser has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. De Visser has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Argenx. Dr. De Visser has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for AstraZeneca.
Zhiwei Tang No disclosure on file
Susan L. Perlman, MD Dr. Perlman has nothing to disclose.
Jiong Shi, MD, FAAN Dr. Shi has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche.
Christopher Gomez, MD, PhD Dr. Gomez has nothing to disclose.
Sheng-Han Kuo, MD, FAAN Dr. Kuo has nothing to disclose.
Murray Grossman, MD, FAAN Dr. Grossman has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology. The institution of Dr. Grossman has received research support from NIH.
John Q. Trojanowski, MD, PhD Dr. Trojanowski has nothing to disclose.
Kimiko Domoto-Reilly, MD Dr. Domoto-Reilly has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for MedBridge. The institution of Dr. Domoto-Reilly has received research support from Lawson Health Research Institute. The institution of Dr. Domoto-Reilly has received research support from NIH. The institution of Dr. Domoto-Reilly has received research support from Biogen. The institution of Dr. Domoto-Reilly has received research support from Lewy Body Dementia Association. The institution of Dr. Domoto-Reilly has received research support from Garvey Institute for Brain Health Solutions. The institution of Dr. Domoto-Reilly has received research support from Cognition Therapeutics. The institution of Dr. Domoto-Reilly has received research support from Takayama Family.
Mark C. Stahl, MD, PhD Dr. Stahl has received personal compensation for serving as an employee of Avidity Biosciences. Dr. Stahl has stock in Avidity Biosciences.
Guangbin Xia, MD, PhD No disclosure on file
Liang Lu, MD, FAAN Dr. Lu has nothing to disclose.
S H. Subramony, MBBS, FAAN Dr. Subramony has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Avidity. Dr. Subramony has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Dyne. Dr. Subramony has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Lupin. Dr. Subramony has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Fallonmedica. Dr. Subramony has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Subramony has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Amicus. Dr. Subramony has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Fulcrum. The institution of Dr. Subramony has received research support from Reata. The institution of Dr. Subramony has received research support from Retrotope. The institution of Dr. Subramony has received research support from Acceleron. The institution of Dr. Subramony has received research support from Biohaven. The institution of Dr. Subramony has received research support from Pharnext. The institution of Dr. Subramony has received research support from Fulcrum. The institution of Dr. Subramony has received research support from National Ataxia Foundation. The institution of Dr. Subramony has received research support from Friedreich Ataxia Research Alliance. The institution of Dr. Subramony has received research support from Muscular Dystrophy Association. The institution of Dr. Subramony has received research support from Univ of Rochester, MDA. The institution of Dr. Subramony has received research support from Virginia Commonwealth Univ (FDA, Wyck Foundation)). The institution of Dr. Subramony has received research support from Children's Hospital, Philadelphia (FDA). The institution of Dr. Subramony has received research support from Houston Methodist (NIH). The institution of Dr. Subramony has received research support from NIHR01 AR076060-01A1 . The institution of Dr. Subramony has received research support from NIH2R42HD089804-04 . The institution of Dr. Subramony has received research support from NIH R01 AR056973 . The institution of Dr. Subramony has received research support from FSHD Society. The institution of Dr. Subramony has received research support from AAVANTI BIO. The institution of Dr. Subramony has received research support from COHAV FL State Dept of Health. The institution of Dr. Subramony has received research support from Avidity. The institution of Dr. Subramony has received research support from PTC. The institution of Dr. Subramony has received research support from Biohaven. The institution of Dr. Subramony has received research support from Fulcrum. The institution of Dr. Subramony has received research support from Vertex. The institution of Dr. Subramony has received research support from Arthrex.
Karla P. Figueroa Ms. Figueroa has nothing to disclose.
Theresa A. Zesiewicz, MD Dr. Zesiewicz has received personal compensation for serving as an employee of Medscape. Dr. Zesiewicz has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Lexeo. Dr. Zesiewicz has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Steminent. Dr. Zesiewicz has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Larimar. Dr. Zesiewicz has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biohaven. Dr. Zesiewicz has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. Dr. Zesiewicz has received intellectual property interests from a discovery or technology relating to health care. Dr. Zesiewicz has received intellectual property interests from a discovery or technology relating to health care. Dr. Zesiewicz has received intellectual property interests from a discovery or technology relating to health care.
Martin E. Sanders, MD No disclosure on file
Tetsuo Ashizawa, MD, FAAN An immediate family member of Dr. Ashizawa has received personal compensation for serving as an employee of Biopath Holdings. The institution of Dr. Ashizawa has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UniQure. The institution of Dr. Ashizawa has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Cadence. Dr. Ashizawa has received personal compensation in the range of $0-$499 for serving as a Consultant for Astellas. The institution of Dr. Ashizawa has received research support from NIH. The institution of Dr. Ashizawa has received research support from National Ataxia Foundation. The institution of Dr. Ashizawa has received research support from Myotonic Dystrophy Foundation. The institution of Dr. Ashizawa has received research support from Biogen.
Giulio M. Pasinetti, MD, PhD No disclosure on file
Gretchen E. Tietjen, MD Dr. Tietjen has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Lundbeck. Dr. Tietjen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for CME Outfitters. An immediate family member of Dr. Tietjen has stock in Johnson & Johnson.
Raymond Y. Lo, MD Dr. Lo has nothing to disclose.
Shin J. Oh, MD, FAAN No disclosure on file
Walter A. Rocca, MD, MPH The institution of Dr. Rocca has received research support from National Institute on Aging - NIH. The institution of Dr. Rocca has received research support from National Heart, Lung, and Blood Institute - NIH.
Bryan T. Klassen, MD The institution of Dr. Klassen has received research support from Insightec.
Rodolfo Savica, MD, PhD, FAAN The institution of Dr. Savica has received research support from ACADIA Pharmaceuticals, Inc.
Ildefonso Rodriguez-Leyva, MD, PhD, FAAN Dr. Rodriguez-Leyva has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Pfizer. Dr. Rodriguez-Leyva has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Laboratorios Carnot. Dr. Rodriguez-Leyva has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Abbvie. Dr. Rodriguez-Leyva has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Lilly Eli and Company. Dr. Rodriguez-Leyva has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Torrent Pharmaceuticals Mexico. Dr. Rodriguez-Leyva has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for abbvie allergan.
George R. Wilmot, MD, PhD Dr. Wilmot has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Larimar Therapeutics. The institution of Dr. Wilmot has received research support from Friedrich Ataxia Research Alliance. The institution of Dr. Wilmot has received research support from National Ataxia Foundation. The institution of Dr. Wilmot has received research support from NIH. The institution of Dr. Wilmot has received research support from Reata. The institution of Dr. Wilmot has received research support from Biohaven Pharmaceuticals.
Elizabeth Nowak No disclosure on file
Lucy E. Farrimond, PhD, BMBCh No disclosure on file
Peng Cheng Han, PhD No disclosure on file
Michelle M. Mielke, PhD Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Merck. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for LabCorp. Dr. Mielke has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Roche. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Siemens Healthineers. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sunbird Bio. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eisai. Dr. Mielke has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Roche. Dr. Mielke has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Novo Nordisk.
Johnathan Cooper-Knock, MD No disclosure on file
J. E. Ahlskog, MD, PhD Dr. Ahlskog has received publishing royalties from a publication relating to health care.
Claudia Sobreira, MD No disclosure on file
Carlo Colosimo, MD No disclosure on file
Philippe Picaut No disclosure on file