2015 Annual Meeting | Dopamine-mediated Neural Plasticity in Motor and Non-motor Circuits
| 08:00 AM - 08:35 AM |
Motor Aspects of Dopamine-Dependent Plasticity in Parkinson’s Disease
David G. Standaert, MD, PhD, FAAN |
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| 08:00 AM - 08:05 AM |
Introduction
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| 08:00 AM - 12:00 PM | Abstract |
001 - De-novo Amantadine Treatment Delays Onset of Dyskinesias in Patients with Parkinson Disease
Maja Relja, MD |
| 08:00 AM - 12:00 PM | Abstract |
002 - Self-ratings of impulsive and compulsive behaviors decrease in Parkinson's patients following deep brain stimulation of the subthalamic nucleus
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| 08:00 AM - 12:00 PM | Abstract |
003 - Learning Processes in Parkinson’s Disease and Healthy Aging
Madeleine Sharp, MD |
| 08:00 AM - 12:00 PM | Abstract |
004 - Effects of Aerobic Exercise on Striatum and Substantia Nigra in Parkinson’s Disease
Ergun Y. Uc, MD |
| 08:00 AM - 12:00 PM | Abstract |
005 - Incidence of Impulsive and Compulsive Behavior Type Adverse Events with Long-term Rotigotine: A Post-hoc Analysis
Angelo Antonini, MD |
| 08:00 AM - 12:00 PM | Abstract |
006 - Putaminal dopamine turnover predicts levodopa-induced motor complications in de novo Parkinson’s disease
Matthias Lohle |
| 08:00 AM - 12:00 PM | Abstract |
007 - Parkinson’s disease progression is associated with increased putaminal serotonin to dopamine transporter ratio: relevance for dyskinesias
Andreas A. Roussakis |
| 08:00 AM - 12:00 PM | Abstract |
008 - Reorganization of cortico-striatal circuits in healthy G2019S LRRK2 carriers
Rick C. Helmich, MD, PhD |
| 08:00 AM - 12:00 PM | Abstract |
009 - Brain structural and functional abnormalities in Parkinson’s disease patients with freezing of gait
Elisabetta Sarasso |
| 08:00 AM - 12:00 PM | Abstract |
010 - Neuroanatomical correlates of cognitive functioning across the Parkinson's Disease cognitive spectrum
Douglas Merkitch |
| 08:00 AM - 12:00 PM | Abstract |
011 - Global Long-Term Registry on Efficacy and Safety of Levodopa-Carbidopa Intestinal Gel in Patients with Advanced Parkinson’s Disease in Routine Care (GLORIA) - Interim Results on Non-Motor Symptoms
Angelo Antonini, MD |
| 08:00 AM - 12:00 PM | Abstract |
012 - Resting connectivity functional MRI in understanding cognitive impairment in Parkinson's disease
Nina M. Browner, MD |
| 08:00 AM - 12:00 PM | Abstract |
013 - Impulse Control Disorders are associated with REM Sleep Behavior Disorder in patients with Parkinson’s Disease: a Video-Polysomnographic Study
Maria Livia Fantini |
| 08:35 AM - 08:40 AM |
Putaminal Dopamine Turnover Predicts Levodopa-Induced Motor Complications in de novo Parkinson’s Diseas
Matthias Lohle |
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| 08:40 AM - 08:45 AM |
Parkinson’s Disease Progression is Associated with Increased Putaminal Serotonin to Dopamine Transporter Ratio: Relevance for Dyskinesias
Andreas A. Roussakis |
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| 08:45 AM - 08:55 AM |
Questions and Answers
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| 08:55 AM - 09:25 AM |
Cellular Mechanisms of Striatal Plasticity in Movement Disorders
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| 09:25 AM - 09:30 AM |
Reorganization of Cortico-striatal Circuits in Healthy G2019S LRRK2 Carriers
Rick C. Helmich, MD, PhD |
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| 09:30 AM - 09:35 AM |
Brain Structural and Functional Abnormalities in Parkinson’s Disease Patients with Freezing of Gait
Elisabetta Sarasso |
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| 09:35 AM - 09:45 AM |
Questions and Answers
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| 09:45 AM - 09:55 AM |
Break
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| 09:55 AM - 10:25 AM |
Non–Motor Aspects of Dopamine-Dependent Plasticity in Parkinson’s Disease
Daniel Weintraub |
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| 10:25 AM - 10:30 AM |
Neuroanatomical Correlates of Cognitive Functioning Across the Parkinson's Disease Cognitive Spectrum
Douglas Merkitch |
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| 10:30 AM - 10:35 AM |
Global Long-term Registry on Efficacy and Safety of Levodopa-Carbidopa Intestinal Gel in Patients with Advanced Parkinson’s Disease in Routine Care (GLORIA) - Interim Results on Non-motor Symptoms
Angelo Antonini, MD |
|
| 10:35 AM - 10:45 AM |
Questions and Answers
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| 10:45 AM - 11:15 AM |
Dopamine-dependent systems and their behavioral consequences in Parkinson's disease: Functional Imaging Studies
James Rowe, BA BM BCh PhD |
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| 11:15 AM - 11:20 AM |
Resting Connectivity Functional MRI in Understanding Cognitive Impairment in Parkinson's Disease
Nina M. Browner, MD |
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| 11:20 AM - 11:25 AM |
Impulse Control Disorders are Associated with REM Sleep Behavior Disorder in Patients with Parkinson’s Disease: a Video-Polysomnographic Study
Maria Livia Fantini |
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| 11:25 AM - 11:35 AM |
Questions and Answers
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| 11:35 AM - 12:00 PM |
Guided Poster Rounds
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| Irene Litvan, MD, FAAN | Dr. Litvan has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Aprinoia. Dr. Litvan has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Lundbeck. Dr. Litvan has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Frontiers in Neurology. Dr. Litvan has received personal compensation in the range of $50,000-$99,999 for serving as a Chief Editor with Frontiers in Neurology. |
| David G. Standaert, MD, PhD, FAAN | Dr. Standaert has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Abbvie, Inc. Dr. Standaert has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Curium Pharma. Dr. Standaert has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Gray Matter Technologies. Dr. Standaert has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi-Aventis. Dr. Standaert has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Theravance, Inc. Dr. Standaert has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for International Parkinson and Movement Disorder Society. The institution of Dr. Standaert has received research support from Abbvie, Inc. The institution of Dr. Standaert has received research support from American Parkinson Disease Association. The institution of Dr. Standaert has received research support from Department of Defense. The institution of Dr. Standaert has received research support from National Institutes of Health. Dr. Standaert has received publishing royalties from a publication relating to health care. Dr. Standaert has received personal compensation in the range of $500-$4,999 for serving as a Speaker with Case Western Reserve. Dr. Standaert has received personal compensation in the range of $500-$4,999 for serving as a Consultant with California Pacific Medical Center. Dr. Standaert has received personal compensation in the range of $500-$4,999 for serving as a Course Instructor with International Parkinson Disease and Movement Disorders Society. Dr. Standaert has received personal compensation in the range of $500-$4,999 for serving as a Reviewer with National Institutes of Health. Dr. Standaert has received personal compensation in the range of $500-$4,999 for serving as a Consultant with Parkinson Study Group. Dr. Standaert has received personal compensation in the range of $500-$4,999 for serving as a Speaker with UCSD. Dr. Standaert has received personal compensation in the range of $500-$4,999 for serving as a Reviewer with Warren Alpert Foundation. Dr. Standaert has a non-compensated relationship as a Chair, Scientific Advisory Board with American Parkinson Disease Association that is relevant to AAN interests or activities. |
| James Rowe, BA BM BCh PhD | James Rowe, BA BM BCh PhD has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. James Rowe, BA BM BCh PhD has received personal compensation in the range of $500-$4,999 for serving as a Consultant for SV Health. James Rowe, BA BM BCh PhD has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Astex. James Rowe, BA BM BCh PhD has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Asceneuron. James Rowe, BA BM BCh PhD has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for GE Healthcare. The institution of James Rowe, BA BM BCh PhD has received research support from Janssen. The institution of James Rowe, BA BM BCh PhD has received research support from Lilly. The institution of James Rowe, BA BM BCh PhD has received research support from AZ Medimmune. James Rowe, BA BM BCh PhD has received publishing royalties from a publication relating to health care. |
| Angelo Antonini, MD | Dr. Antonini has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for BIAL. Dr. Antonini has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for ABBVIE. Dr. Antonini has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for UCB. Dr. Antonini has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for THERAVANCE. Dr. Antonini has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for ROCHE. Dr. Antonini has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for ABBVIE. Dr. Antonini has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for ZAMBON. Dr. Antonini has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for BOEHRINGER. |
| Daniel Weintraub | Daniel Weintraub has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Clintrex. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Janssen. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sage. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Scion. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Signant. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sunovion. Daniel Weintraub has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Modality.ai. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Cerevel. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for CuraSen. Daniel Weintraub has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Takeda. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Boehringer Ingelheim. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Daniel Weintraub has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Acadia. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Movement Disorder Society. The institution of Daniel Weintraub has received research support from NIH. The institution of Daniel Weintraub has received research support from Fox Foundation. The institution of Daniel Weintraub has received research support from IPMDS. Daniel Weintraub has received intellectual property interests from a discovery or technology relating to health care. |
| Douglas Merkitch | No disclosure on file |
| Elisabetta Sarasso | Elisabetta Sarasso has nothing to disclose. |
| Matthias Lohle | No disclosure on file |
| Nina M. Browner, MD | The institution of Dr. Browner has received research support from Parkinson Foundation Center of Excellence Grant. The institution of Dr. Browner has received research support from Parkinson Foundation Community Outreach Grant . |
| Maria Livia Fantini | No disclosure on file |
| Rick C. Helmich, MD, PhD | No disclosure on file |
| Andreas A. Roussakis | No disclosure on file |
| No disclosure on file | |
| Bastiaan R. Bloem, MD, PhD | No disclosure on file |
| Lars Bauer, MD | No disclosure on file |
| Ergun Y. Uc, MD | An immediate family member of Dr. Uc has received personal compensation in the range of $500-$4,999 for serving as an officer or member of the Board of Directors for American Board of Pediatrics. The institution of Dr. Uc has received research support from Department of Veterans Affairs. The institution of Dr. Uc has received research support from Department of Defense. The institution of an immediate family member of Dr. Uc has received research support from NIH. The institution of Dr. Uc has received research support from NIH. The institution of Dr. Uc has received research support from NIH. The institution of Dr. Uc has received research support from Parkinson's Foundation. The institution of Dr. Uc has received research support from NIH. |
| Steven W. Anderson, PhD | Dr. Anderson has nothing to disclose. |
| Maja Relja, MD | No disclosure on file |
| Teri R. Thomsen, MD | Dr. Thomsen has nothing to disclose. |
| Bryan A. Bernard, PhD | Dr. Bernard has nothing to disclose. |
| Franck Durif, MD, PhD | No disclosure on file |
| Maurizio Zibetti | No disclosure on file |
| Heinz Reichmann, MD, FAAN | Dr. Reichmann has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Bial. Dr. Reichmann has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Zambon. Dr. Reichmann has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Kyowa. Dr. Reichmann has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Bial. Dr. Reichmann has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Zambon. Dr. Reichmann has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Kyowa. Dr. Reichmann has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Bial. Dr. Reichmann has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Zambon. Dr. Reichmann has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for UCB. Dr. Reichmann has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Thieme. Dr. Reichmann has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Wissenschaftsverlag. |
| Nir Giladi, MD, FAAN | Dr. Giladi has received personal compensation in the range of $0-$499 for serving as a Consultant for Sionara. Dr. Giladi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for NeuroDerm. Dr. Giladi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Pharma2B. Dr. Giladi has stock in Vibrant. Dr. Giladi has stock in Lysosomal Therapeutics . The institution of Dr. Giladi has received research support from The Michael J Fox Foundation. The institution of Dr. Giladi has received research support from The National Parkinson Foundation. The institution of Dr. Giladi has received research support from The European Union . The institution of Dr. Giladi has received research support from The Israel Science Foundation. The institution of Dr. Giladi has received research support from Biogen . The institution of Dr. Giladi has received research support from Ionis. The institution of Dr. Giladi has received research support from Sieratzki Family Foundation . The institution of Dr. Giladi has received research support from The Aufzien Academic Center in Tel-Aviv University. |
| Matthew Rizzo, MD, FAAN | The institution of Dr. Rizzo has received research support from NIH. |
| Alexander Storch, MD | No disclosure on file |
| Paola Piccini, MD | No disclosure on file |
| Alessandro Cicolin, MD | No disclosure on file |
| Federica Agosta | Federica Agosta has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Philips. Federica Agosta has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier INC. |
| Avner Thaler, MD | The institution of Dr. Thaler has received personal compensation in the range of $500-$4,999 for serving as a Consultant for ABBVIE. The institution of Dr. Thaler has received research support from MJFF. |
| Nicolas Vitello | No disclosure on file |
| Philippe P. Derost | No disclosure on file |
| Sarah J. Rathman, DO | Mrs. Inbornone has nothing to disclose. |
| Warren Darling | No disclosure on file |
| Jeffrey Dawson | Jeffrey Dawson has received personal compensation in the range of $500-$4,999 for serving as a Consultant for iotaMotion. Jeffrey Dawson has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Congress of Neurological Surgeons. The institution of Jeffrey Dawson has received research support from Department of Veterans Affairs. The institution of Jeffrey Dawson has received research support from NIH. |
| Nelleke C. Van Wouwe, PhD | No disclosure on file |
| Ana Marques | No disclosure on file |
| Giancarlo Comi, MD | Dr. Comi has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Janssen. Dr. Comi has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Bristol Myers Squibb. Dr. Comi has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Comi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Janssen. Dr. Comi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Bristol Myers Squibb. Dr. Comi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Novartis. Dr. Comi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Aspen Healthcare. Dr. Comi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Sanofi. Dr. Comi has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Sanofi. Dr. Comi has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Rewind. |
| Elisa Canu | The institution of Elisa Canu has received research support from Italian Ministry of Health . |
| Jennifer G. Goldman, MD, MS, FAAN | Dr. Goldman has received personal compensation in the range of $500-$4,999 for serving as an officer or member of the Board of Directors for Parkinson's Foundation Scientific Advisory Board. The institution of Dr. Goldman has received research support from Michael J. Fox Foundation. The institution of Dr. Goldman has received research support from Parkinson's Foundation. |
| Kallol R. Chaudhuri, MD, FRCP | Dr. Chaudhuri has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Abbvie, Acadia, GSK, Scion, Britannia , Lobsor. Dr. Chaudhuri has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Abbvie, Britannia, Scion, Sunovion, UCB, . Dr. Chaudhuri has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Abbvie, Britannia, UCB, Zambon. Dr. Chaudhuri has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for NPJ PD journal. The institution of Dr. Chaudhuri has received research support from Britania Pharmaceuticals, AbbVie, UCB, GKC, Bial, Aacdemic grants: EU, IMI EU, Horizon 2020, Parkinson's UK, NIHR, PDNMG, EU (Horizon 2020), Kirby Laing Foundation, NPF, MRC, Wellcome Trust. |
| Miguel Ulla, MD, PhD | No disclosure on file |
| Werner Poewe, MD | Werner Poewe, MD has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Affiris . Werner Poewe, MD has received personal compensation in the range of $50,000-$99,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alterity, AbbVie, BIAL, Biogen, Britannia, Lilly, Lundbeck, Neuroderm, Neurocrine, Denali Pharmaceuticals, ,Roche, Takeda, UCB and Zambon . Werner Poewe, MD has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for AbbVie, Britannia, BIAL, STADA, Lundbeck, Zambon. The institution of Werner Poewe, MD has received research support from MJFF; EU Horizon programme. Werner Poewe, MD has a non-compensated relationship as a Committee member with Movement Disorder Society that is relevant to AAN interests or activities. |
| Andrea Falini | No disclosure on file |
| Leonardo Lopiano, MD | No disclosure on file |
| Daniel O. Claassen, MD, FAAN | Dr. Claassen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Spark . The institution of Dr. Claassen has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Alterity. Dr. Claassen has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for University of Michigan. Dr. Claassen has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for HD Insights. The institution of Dr. Claassen has received research support from NIH. The institution of Dr. Claassen has received research support from CHDI. The institution of Dr. Claassen has received research support from HDSA. The institution of Dr. Claassen has received research support from Department of Defense. The institution of Dr. Claassen has received research support from CHDI. The institution of Dr. Claassen has received research support from Genentech/ Roche. |
| Joel Kline | No disclosure on file |
| Ashley Yegin | No disclosure on file |
| Arthur Kramer | No disclosure on file |
| Glenn T. Stebbins, PhD | Dr. Stebbins has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Biogen. Dr. Stebbins has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Partners Healthcare System. Dr. Stebbins has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for CHDI. The institution of Dr. Stebbins has received research support from Department of Defense. Dr. Stebbins has received research support from Cleveland Clinic Health Systems. Dr. Stebbins has received personal compensation in the range of $500-$4,999 for serving as a Course Director with MDS. |
| Madeleine Sharp, MD | No disclosure on file |
| Lidia Sarro, MD | No disclosure on file |
| Mahnaz Asgharnejad, PharmD | Mahnaz Asgharnejad, PharmD has received personal compensation for serving as an employee of Takeda Pharmaceuticals. Mahnaz Asgharnejad, PharmD has stock in GlaxoSmithKline. Mahnaz Asgharnejad, PharmD has stock in Takeda Pharmaceuticals. |
| Lars Bergmann, MD | No disclosure on file |
| Massimo Filippi, MD, FAAN | Dr. Filippi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Alexion, Almirall, Biogen, Merck, Novartis, Roche, Sanofi. Dr. Filippi has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion, Biogen, Bristol-Myers Squibb, Merck, Novartis, Roche, Sanofi, Sanofi-Aventis, Sanofi-Genzyme, Takeda. Dr. Filippi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Bayer, Biogen, Celgene, Chiesi Italia SpA, Eli Lilly, Genzyme, Janssen, Merck-Serono, Neopharmed Gentili, Novartis, Novo Nordisk, Roche, Sanofi, Takeda, and TEVA. Dr. Filippi has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Springer Nature. The institution of Dr. Filippi has received research support from Biogen Idec, Merck-Serono, Novartis, Roche, the Italian Ministry of Health, the Italian Ministry of University and Research, and Fondazione Italiana Sclerosi Multipla. |
| Karen S. Marder, MD, MPH, FAAN | Dr. Marder has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech. Dr. Marder has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Parkinson's Foundation . Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for CHDI. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for PTC therapeutics. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Springer LTD. The institution of Dr. Marder has received research support from Vaccinex. The institution of Dr. Marder has received research support from Genentech. The institution of Dr. Marder has received research support from Triplet Therapeutics. The institution of Dr. Marder has received research support from Prilenia. |
| Anat Mirelman | Anat Mirelman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Abbvie . Anat Mirelman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Bial. The institution of Anat Mirelman has received research support from Department of Defense. The institution of Anat Mirelman has received research support from MJFF. The institution of Anat Mirelman has received research support from JPND. The institution of Anat Mirelman has received research support from EU-Horizon 2020. |
| Marios Politis, MD | No disclosure on file |
| Michelle Voss | No disclosure on file |