2015 Annual Meeting | Future Therapies: How We Will Be Treating, Preventing, and Curing Epilepsy in the Year 2025
| 01:00 PM - 01:15 PM |
Introduction
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| 01:00 PM - 05:00 PM | Abstract |
001 - Assessment of the Anticonvulsant Effects and Tolerability Profile of Cannabidiol: GW Pharmaceuticals’ Preclinical Program
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| 01:00 PM - 05:00 PM | Abstract |
002 - Intractable reflex epilepsy treated successfully with deep brain stimulation
Anteneh M. Feyissa, MD, MSc, FAAN |
| 01:00 PM - 05:00 PM | Abstract |
003 - Optogenetic Neuromodulation
Genko Oyama, MD, PhD, FAAN |
| 01:00 PM - 05:00 PM | Abstract |
004 - B and Plasma cells and Meningeal follicles are a part of neuro-inflammatory mechanisms associated with Rasmussen’s Encephalitis: New clues about pathogenesis
Anupama Kumar, PhD |
| 01:00 PM - 05:00 PM | Abstract |
005 - Does a Standardized Multidisciplinary Approach Improve Outcomes for Children with NMDA Receptor Antibody Encephalitis? A Preliminary Assessment of a Single Center Experience
Mered Parnes, MD |
| 01:00 PM - 05:00 PM | Abstract |
006 - Indomethacin increases the latency to seizure onset and decreased the number of seizures in zebrafish seizure model
Patricia G. Barbalho, PhD |
| 01:00 PM - 05:00 PM | Abstract |
007 - Role of NOX2 in seizure susceptibility of mice following systemic inflammation
Hung-Ming Wu |
| 01:00 PM - 05:00 PM | Abstract |
008 - Everolimus long-term safety and efficacy in patients with subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex (TSC): final analysis of a phase 2 study
David N. Franz, MD |
| 01:00 PM - 05:00 PM | Abstract |
009 - Targeted Treatment of Migrating Partial Seizures of Infancy with Quinidine
David Bearden, MD |
| 01:00 PM - 05:00 PM | Abstract |
010 - Decreased amygdala resting state functional connectivity in patients with left temporal lobe epilepsy
Jane B. Allendorfer, PhD |
| 01:00 PM - 05:00 PM | Abstract |
011 - Using Neural Networks to Predict the Effects and Guide the Application of Transcranial Direct Current Stimulation
David J. Fischer, MD |
| 01:00 PM - 05:00 PM | Abstract |
013 - Novel Ambulatory EMG-based GTC Seizure Detection Device for Home & Hospital Use
Jose E. Cavazos, MD, PhD |
| 01:05 PM - 01:35 PM |
Development of Anti-Inflammatory and Immune Modulatory Therapies for Epilepsy
Karen Wilcox, PhD |
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| 01:35 PM - 01:40 PM |
Indomethacin increases the latency to seizure onset and decreased the number of seizures in zebrafish seizure model
Patricia G. Barbalho, PhD |
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| 01:40 PM - 01:45 PM |
Role of NOX2 in seizure susceptibility of mice following systemic inflammation
Hung-Ming Wu |
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| 01:45 PM - 01:55 PM |
Questions and Answers
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| 01:55 PM - 02:25 PM |
Cell Signaling Modulators as Novel Disease Modifying Therapies for Epilepsy
Anne E. Anderson, MD |
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| 02:25 PM - 02:30 PM |
Everolimus long-term safety and efficacy in patients with subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex (TSC): final analysis of a phase 2 study
David N. Franz, MD |
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| 02:30 PM - 02:35 PM |
Targeted Treatment of Migrating Partial Seizures of Infancy with Quinidine
David Bearden, MD |
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| 02:45 PM - 02:55 PM |
Questions and Answers
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| 02:45 PM - 02:55 PM |
Break
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| 02:55 PM - 03:25 PM |
Lighting the Way: Optogenetic Approaches for Treatment of Epilepsy
Ivan Soltesz, PhD |
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| 03:25 PM - 03:30 PM |
Decreased amygdala resting state functional connectivity in patients with left temporal lobe epilepsy
Jane B. Allendorfer, PhD |
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| 03:30 PM - 03:35 PM |
Using Neural Networks to Predict the Effects and Guide the Application of Transcranial Direct Current Stimulation
David J. Fischer, MD |
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| 03:35 PM - 03:45 PM |
Questions and Answers
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| 03:45 PM - 04:15 PM |
Seizure Detection/Prediction Devices and Therapies
Gregory A. Worrell, MD |
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| 04:15 PM - 04:20 PM |
Combining Electroencephalographic Time-Frequency and Source Analysis Methods for Improve Epileptogenic Zones Localization
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| 04:20 PM - 04:25 PM |
Novel Ambulatory EMG-based GTC Seizure Detection Device for Home & Hospital Use
Jose E. Cavazos, MD, PhD |
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| 04:25 PM - 04:35 PM |
Questions and Answers
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| 04:35 PM - 05:00 PM |
Guided Poster Rounds
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| Amy R. Brooks-Kayal, MD, FAAN | Dr. Brooks-Kayal has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for ABPN. Dr. Brooks-Kayal has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Annals of Neurology. Dr. Brooks-Kayal has stock in Johnson and Johnson. The institution of Dr. Brooks-Kayal has received research support from NINDS. |
| Anne E. Anderson, MD | No disclosure on file |
| Gregory A. Worrell, MD | Dr. Worrell has received stock or an ownership interest from NeuroOne Inc.. Dr. Worrell has received stock or an ownership interest from Cadence Neuroscience Inc. The institution of Dr. Worrell has received research support from NIH. The institution of Dr. Worrell has received research support from Medtronic Inc.. The institution of Dr. Worrell has received research support from Neuropace Inc,. The institution of Dr. Worrell has received research support from Epilepsy Foundation of America. Dr. Worrell has received intellectual property interests from a discovery or technology relating to health care. Dr. Worrell has received intellectual property interests from a discovery or technology relating to health care. |
| Ivan Soltesz, PhD | No disclosure on file |
| Karen Wilcox, PhD | No disclosure on file |
| Jose E. Cavazos, MD, PhD | Dr. Cavazos has received stock or an ownership interest from Brain Sentinel . The institution of Dr. Cavazos has received research support from NIH. |
| Jane B. Allendorfer, PhD | The institution of Dr. Allendorfer has received research support from National Institutes of Health. The institution of Dr. Allendorfer has received research support from Evelyn F. McKnight Brain Institute. The institution of Dr. Allendorfer has received research support from LivaNova, Inc. Dr. Allendorfer has received personal compensation in the range of $500-$4,999 for serving as a Speaker with Cleveland Clinic. Dr. Allendorfer has received personal compensation in the range of $0-$499 for serving as a Examiner with University of Auckland. Dr. Allendorfer has received personal compensation in the range of $500-$4,999 for serving as a Speaker with International League Against Epilepsy. Dr. Allendorfer has received personal compensation in the range of $500-$4,999 for serving as a Grant Reviewer with Department of Defense. Dr. Allendorfer has a non-compensated relationship as a Scientific Program Committee Member with American Epilepsy Society that is relevant to AAN interests or activities. Dr. Allendorfer has a non-compensated relationship as a Editorial Board Member with Epilepsy and Behavior Reports that is relevant to AAN interests or activities. |
| Hung-Ming Wu | No disclosure on file |
| David J. Fischer, MD | Dr. Fischer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alphasights. Dr. Fischer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Atheneum. Dr. Fischer has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Drazin & Warshaw. The institution of Dr. Fischer has received research support from NIH/NINDS. The institution of Dr. Fischer has received research support from 好色先生. The institution of Dr. Fischer has received research support from Neurocritical Care Society. |
| No disclosure on file | |
| Patricia G. Barbalho, PhD | No disclosure on file |
| David N. Franz, MD | No disclosure on file |
| David Bearden, MD | Dr. Bearden has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Bearden has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Praxis. Dr. Bearden has received personal compensation in the range of $100,000-$499,999 for serving as an Expert Witness for law firms. |
| Adam L. Hartman, MD, FAAP, FAES, FAAN | Dr. Hartman has received personal compensation for serving as an employee of NINDS/NIH. |
| Iscia Lopes-Cendes, MD, PhD | No disclosure on file |
| Darcy Krueger, MD | Dr. Krueger has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for NobelPharma USA. Dr. Krueger has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for RegenxBio. Dr. Krueger has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Novartis Pharmaceuticals. Dr. Krueger has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Greenwich Biosciences. The institution of Dr. Krueger has received research support from Greenwich Bioscience. The institution of Dr. Krueger has received research support from Marinus Pharmaceuticals. The institution of Dr. Krueger has received research support from National Institutes of Health. The institution of Dr. Krueger has received research support from Food and Drug Administration. The institution of Dr. Krueger has received research support from TSC Alliance. |
| Trung P. Nguyen, MD | The institution of Dr. Nguyen has received research support from National Institute on Aging. The institution of Dr. Nguyen has received research support from Texas Alzheimer's Research and Care Consortium. The institution of Dr. Nguyen has received research support from Biogen. |
| Ethan M. Goldberg, MD, PhD | Dr. Goldberg has nothing to disclose. |
| Michael D. Fox, MD, PhD | Dr. Fox has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Wiley. |
| Carlos A. Pardo-Villamizar, MD | The institution of Dr. Pardo-Villamizar has received research support from National Institutes of Health. The institution of Dr. Pardo-Villamizar has received research support from Bart McLean Fund for Neuroimmunology Research . |
| Calixto Machado, MD, PhD, FAAN | Dr. Machado has nothing to disclose. |
| Alvaro Pascual-Leone, MD, PhD, FAAN | Dr. Pascual-Leone has received personal compensation for serving as an employee of Linus Health. Dr. Pascual-Leone has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Magstim. Dr. Pascual-Leone has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Neuroelectrics. Dr. Pascual-Leone has received personal compensation in the range of $500-$4,999 for serving as a Consultant for TetraNeuron. Dr. Pascual-Leone has received personal compensation in the range of $500-$4,999 for serving as a Consultant for MedRhythms. Dr. Pascual-Leone has received personal compensation in the range of $100,000-$499,999 for serving as an officer or member of the Board of Directors for Linus Health. Dr. Pascual-Leone has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Annals of Neurology. Dr. Pascual-Leone has stock in TI Solutions. The institution of Dr. Pascual-Leone has received research support from NIH. The institution of Dr. Pascual-Leone has received research support from NSF. The institution of Dr. Pascual-Leone has received research support from Brightfocus Foundation . Dr. Pascual-Leone has received intellectual property interests from a discovery or technology relating to health care. Dr. Pascual-Leone has received publishing royalties from a publication relating to health care. |
| Jeffrey Binder, MD | No disclosure on file |
| Karen Agricola, FNP | No disclosure on file |
| Anupama Kumar, PhD | No disclosure on file |
| Genko Oyama, MD, PhD, FAAN | Dr. Oyama has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Medtronic. Dr. Oyama has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Boston Scientific. Dr. Oyama has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Otsuka Pharmaceutical Co. Ltd.. Dr. Oyama has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Sumitomo Dainippon Pharma Co. Ltd.. Dr. Oyama has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Eisai Co., Ltd.. Dr. Oyama has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Takeda Pharmaceutical Company LTD.. Dr. Oyama has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Kyowa Hakko Kirin Co. Ltd.. Dr. Oyama has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for AbbVie, Inc. The institution of Dr. Oyama has received research support from AbbVie, Inc. The institution of Dr. Oyama has received research support from GLORY LTD. The institution of Dr. Oyama has received research support from Kirin Company LTD. The institution of Dr. Oyama has received research support from Mitsubishi UFJ Lease & Finance Company LTD. The institution of Dr. Oyama has received research support from Sunwels Co., Ltd. The institution of Dr. Oyama has received research support from Ohara Pharmaceutical Co.,Ltd.. The institution of Dr. Oyama has received research support from PARKINSON Laboratories Co., Ltd.. |
| Mered Parnes, MD | Dr. Parnes has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Teva Pharmaceuticals. Dr. Parnes has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Teva Pharmaceuticals. The institution of Dr. Parnes has received research support from NIH. The institution of Dr. Parnes has received research support from Alexion. |
| Maria I. Reyes-Mantilla, MD | Dr. Reyes-Mantilla has nothing to disclose. |
| Jeffrey W. Britton, MD, FAAN | Dr. Britton has received personal compensation in the range of $0-$499 for serving as a Online course with American Clinical Neurophysiology Society. |
| Dennis J. Dlugos, MD | Dr. Dlugos has received research support from NIH. The institution of Dr. Dlugos has received research support from The Epilepsy Study Consortium. |
| Noah Berkowitz | No disclosure on file |
| Katherine D. Holland, MD, PhD | No disclosure on file |
| Nobutaka Hattori, MD, PhD, FANA | Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving as a Consultant for PARKINSON Laboratories Co., Ltd. Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Kyowa Kirin Co., Ltd. . Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for TEIJIN PHARMA LIMITED.. Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sumitomo Dainippon Pharma Co., Ltd.. Prof. Hattori has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Ono Pharmaceutical Co., Ltd.. Prof. Hattori has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Kyowa Kirin Co., Ltd. . Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for AbbVie GK. Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Eisai Co., Ltd. . Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Otsuka Holdings Co.,Ltd.. Prof. Hattori has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Ono Pharmaceutical Co., Ltd.. Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Eisai Co., Ltd. . Prof. Hattori has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Sumitomo Dainippon Pharma Co., Ltd.. Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Takeda Pharma Co., Ltd.. Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Novartis Pharma K.K.. Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for DAIICHI SANKYO Co., Ltd.. Prof. Hattori has received stock or an ownership interest from PARKINSON Laboratories Co., Ltd. The institution of Prof. Hattori has received research support from Japan Society for the Promotion of Science (JSPS). The institution of Prof. Hattori has received research support from Japan Agency for Medical Research and Development (AMED). The institution of Prof. Hattori has received research support from Japan Science and Technology Agency, Health Labour Sciences Research Grant. The institution of Prof. Hattori has received research support from Japan Science and Technology Agency (JST). The institution of Prof. Hattori has received research support from Kyowa Kirin Co.,Ltd.. The institution of Prof. Hattori has received research support from Medtronic, Inc.. The institution of Prof. Hattori has received research support from Boston Scientific Corporation. The institution of Prof. Hattori has received research support from TEIJIN PHARMA LIMITED.. The institution of Prof. Hattori has received research support from AbbVie GK. The institution of Prof. Hattori has received research support from FP Pharmaceutical Corporation. The institution of Prof. Hattori has received research support from Dai-Nippon Sumitomo Pharma Co.,Ltd. The institution of Prof. Hattori has received research support from Nihon Medi-physics Co.,Ltd.,. The institution of Prof. Hattori has received research support from Eisai Co.,Ltd. . The institution of Prof. Hattori has received research support from Kirin Holdings Company, Limited. The institution of Prof. Hattori has received research support from Mitsubishi UFJ Trust and Banking Corporation. The institution of Prof. Hattori has received research support from GLORY LTD.. The institution of Prof. Hattori has received research support from Nippon Life Insurance Company. The institution of Prof. Hattori has received research support from Otsuka Pharmaceutical, Co.,Ltd. The institution of Prof. Hattori has received research support from AbbVie GK,. The institution of Prof. Hattori has received research support from Meiji Seika Pharma Co., Ltd.. The institution of Prof. Hattori has received research support from Ono Pharmaceutical Co., Ltd.. The institution of Prof. Hattori has received research support from FUJIFILM Wako Pure Chemical Corporation. The institution of Prof. Hattori has received research support from Sunwels,Inc.. The institution of Prof. Hattori has received research support from OHARA Pharmaceutical Co.,Ltd.. The institution of Prof. Hattori has received research support from PARKINSON Laboratories Co., Ltd.. The institution of Prof. Hattori has received research support from Ono Pharmaceutical Co., Ltd.. Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving as a Team Leader with RIKEN Center for Brain Science. Prof. Hattori has received personal compensation in the range of $500-$4,999 for serving as a Program officer with AMED: Japan Agency for Medical Research and Development. |
| Squire M. Stead, MD, PhD | No disclosure on file |
| Anteneh M. Feyissa, MD, MSc, FAAN | Dr. Feyissa has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Neurelis. |
| Jamie J. Van Gompel, MD | Jamie J. Van Gompel, MD has stock in Neuroone. |
| Eyal Muscal | Eyal Muscal has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for sobi. An immediate family member of Eyal Muscal has stock in pfizer. |
| Luke Whitmire, PhD | No disclosure on file |
| Amber J. Stocco, MD | No disclosure on file |
| Xiaoyang Lan, PhD | No disclosure on file |
| Stephen Wright | No disclosure on file |
| Wan-Yu Huang | No disclosure on file |
| Thomas A. Hill, MD | No disclosure on file |
| Jerzy P. Szaflarski, MD, PhD, FAAN | Dr. Szaflarski has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UCB Pharma. Dr. Szaflarski has received personal compensation in the range of $500-$4,999 for serving as a Consultant for LivaNova Inc. Dr. Szaflarski has received personal compensation in the range of $500-$4,999 for serving as a Consultant for PureTech Health. Dr. Szaflarski has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Gidley, Sarli & Marusak, LLP. Dr. Szaflarski has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier. Dr. Szaflarski has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Law Firm. Dr. Szaflarski has stock in AdCel Biopharma, LLC. Dr. Szaflarski has stock in iFovea. |
| Lawrence W. Ver Hoef, MD | Dr. Ver Hoef has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Bowling & Christiansen. The institution of Dr. Ver Hoef has received research support from NIH. The institution of Dr. Ver Hoef has received research support from AES. |
| Claudia V. Maurer-Morelli, PhD | No disclosure on file |
| Marissa P. DiGiovine, MD | The institution of Dr. DiGiovine has received research support from HRSA. |
| Michael Girouard | No disclosure on file |