2015 Annual Meeting | Movement Disorders: Genetics
| 01:00 PM - 02:45 PM | Abstract |
002 - Phosphorylated pS1292 LRRK2 to Total LRRK2 Concentration Ratio in Urine Exosomes Distinguishes LRRK2-PD and Idiopathic PD
Roy Alcalay, MD |
| 01:00 PM - 02:45 PM | Abstract |
003 - Glucocerebrosidase activity in Parkinson disease with and without GBA mutations
Roy Alcalay, MD |
| 01:00 PM - 02:45 PM | Abstract |
004 - Zebrafish (Danio rerio) as a model for Glucocerebrosidase 1 (GBA1) deficiency
Oliver E. Bandmann, MD, PhD, FAAN |
| 01:00 PM - 02:45 PM | Abstract |
005 - Association Studies of Neuropathologically-Confirmed Cases and Controls Reveals that the PARK10 Locus is a Major Contributor to Sporadic Parkinson disease.
Jeffery Vance, MD, PhD |
| 01:00 PM - 02:45 PM | Abstract |
006 - Variants associated with Gaucher disease in multiple system atrophy
Jun Mitsui |
| 01:00 PM - 02:45 PM | Abstract |
007 - Short hairpin RNA targeting endogenous alpha-synuclein prevents degeneration of dopaminergic neurons in the rat rotenone model of Parkinson's disease
Edward Burton |
| Tanya Simuni, MD, FAAN | Dr. Simuni has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for cadia, AcureX, Adamas, AskBio, Amneal, Blue Rock Therapeutics, Caraway Therapeutics, Critical Path for Parkinson's Consortium (CPP), Denali, Michael J Fox Foundation, Neuroderm, Sanofi, Sinopia, Roche, Takeda and Vanqua Bio. Dr. Simuni has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for of Koneksa, Neuroderm, Sanofi, UCB, AcureX, Adamas, AskBio, Biohaven, Denali, GAIN, Neuron23 and Roche. Dr. Simuni has received research support from Amneal, Biogen, Neuroderm, Prevail, Roche, and UCB and an investigator for NINDS, MJFF, Parkinson's Foundation. |
| Fredy J. Revilla, MD, FAAN | Dr. Revilla has received personal compensation in the range of $500-$4,999 for serving as a Consultant for TEVA . Dr. Revilla has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for TEVA . |
| Cheryl H. Waters, MD, FAAN | Dr. Waters has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Acadia. Dr. Waters has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Kyowa. Dr. Waters has received personal compensation in the range of $500-$4,999 for serving as a Consultant for US world meds. Dr. Waters has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alexza. Dr. Waters has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Acorda. Dr. Waters has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Acadia. Dr. Waters has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Neurocrine. Dr. Waters has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Bial. Dr. Waters has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for US world meds. Dr. Waters has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Lundbeck. Dr. Waters has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Adamas. Dr. Waters has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Sunovion. Dr. Waters has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Amneal. |
| Kimford J. Meador, MD, FAAN | The institution of Dr. Meador has received research support from NIH. The institution of Dr. Meador has received research support from Eisai. The institution of Dr. Meador has received research support from Medtronics. The institution of Dr. Meador has received research support from The Epilepsy Consortium. |
| Dennis W. Dickson, MD | Dr. Dickson has nothing to disclose. |
| Juan C. Troncoso, MD | No disclosure on file |
| Deborah C. Mash, PhD | No disclosure on file |
| Bernardino Ghetti, MD | No disclosure on file |
| Blair Ford, MD, FAAN | No disclosure on file |
| Ted M. Dawson, MD, PhD, FAAN | Dr. Dawson has received personal compensation in the range of $50,000-$99,999 for serving as an officer or member of the Board of Directors for Valted Seq Inc. An immediate family member of Dr. Dawson has received personal compensation in the range of $100,000-$499,999 for serving as an officer or member of the Board of Directors for Valted Seq Inc. An immediate family member of Dr. Dawson has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for eNeuro. Dr. Dawson has stock in Valted Seq. Dr. Dawson has stock in American Gene Technologies International Inc. Dr. Dawson has stock in Inhibikase Therapeutics, Inc. Dr. Dawson has stock in D&D Pharmatech. Dr. Dawson has stock in Abbvie. An immediate family member of Dr. Dawson has stock in Valted Seq Inc. An immediate family member of Dr. Dawson has stock in Inhibikase Therapeutics. An immediate family member of Dr. Dawson has stock in D&D Pharmatech. The institution of Dr. Dawson has received research support from Sun Pharmaceutical Industries Ltd. The institution of Dr. Dawson has received research support from Aevum. Dr. Dawson has received intellectual property interests from a discovery or technology relating to health care. An immediate family member of Dr. Dawson has received intellectual property interests from a discovery or technology relating to health care. Dr. Dawson has received personal compensation in the range of $100,000-$499,999 for serving as a Advisor with Mitokinin. |
| Stanley Fahn, MD, FAAN | Dr. Fahn has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Stoparkinson Healthcare Systems, LLC; . Dr. Fahn has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Retrophin Inc . Dr. Fahn has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Springer Publishers . Dr. Fahn has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Kirkland & Ellis. Dr. Fahn has received publishing royalties from a publication relating to health care. |
| Alexis Brice, MD | Dr. Brice has received personal compensation in the range of $100,000-$499,999 for serving as an officer or member of the Board of Directors for ICM. |
| Thomas Beach | Thomas Beach has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Vivid Genomics. Thomas Beach has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Roche Diagnostics. The institution of Thomas Beach has received research support from National Institutes of Health. The institution of Thomas Beach has received research support from Michael J Fox Foundation . The institution of Thomas Beach has received research support from State of Arizona. |
| Hiroshi Takashima, MD, PhD | Dr. Takashima has nothing to disclose. |
| Owen A. Ross, PhD | Dr. Ross has nothing to disclose. |
| James B. Leverenz, MD, FAAN | Dr. Leverenz has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Acadia. Dr. Leverenz has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Leverenz has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eisai. |
| William C. Nichols, PhD | No disclosure on file |
| William K. Scott, MD | No disclosure on file |
| Gary W. Beecham, PhD | The institution of Dr. Beecham has received research support from NIH. The institution of an immediate family member of Dr. Beecham has received research support from NIH. |
| Pietro Mazzoni, MD, PhD | No disclosure on file |
| No disclosure on file | |
| Thomas J. Montine, MD, PhD | Dr. Montine has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Enable Medicine. Dr. Montine has stock in Enable Medicine. The institution of Dr. Montine has received research support from NIH. The institution of Dr. Montine has received research support from MJFF. Dr. Montine has received intellectual property interests from a discovery or technology relating to health care. Dr. Montine has received publishing royalties from a publication relating to health care. |
| Shoji Tsuji, MD, PhD | The institution of Dr. Tsuji has received research support from Novelpharma Co. Ltd.. |
| Oren Levy, MD | Dr. Levy has received personal compensation for serving as an employee of Regeneron Pharmaceuticals . Dr. Levy has stock in Regeneron Pharmaceuticals . |
| Harry Vinters | No disclosure on file |
| John Q. Trojanowski, MD, PhD | Dr. Trojanowski has nothing to disclose. |
| Wendy Chung, MD, PhD | No disclosure on file |
| Derek Dykxhoorn, PhD | No disclosure on file |
| Ichiro Yabe, MD, PhD | No disclosure on file |
| Guy A. Rouleau, MD, PhD, FAAN | Dr. Rouleau has received personal compensation in the range of $500-$4,999 for serving as a Consultant for NovoNordisk. Dr. Rouleau has received personal compensation in the range of $5,000-$9,999 for serving as an officer or member of the Board of Directors for AL-S Pharma. |
| Samuel Goldman, MD, MPH | Dr. Goldman has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Littlepage Booth Leckman. The institution of Dr. Goldman has received research support from Michael J Fox Foundation. The institution of Dr. Goldman has received research support from US Department of Defense. The institution of Dr. Goldman has received research support from US Veterans Administration. The institution of Dr. Goldman has received research support from National Institutes of Health. The institution of Dr. Goldman has received research support from Health Resources and Services Administration. The institution of Dr. Goldman has received research support from American Academy of Pediatrics. Dr. Goldman has received personal compensation in the range of $100,000-$499,999 for serving as a Professor with University of California San Francisco. Dr. Goldman has received personal compensation in the range of $100,000-$499,999 for serving as a Staff Physician with San Francisco Veterans Affairs Health Care System. |
| Tatiana Foroud, PhD | The institution of Dr. Foroud has received research support from NIH. The institution of Dr. Foroud has received research support from Michael J. Fox Foundation. The institution of Dr. Foroud has received research support from Parkinson Foundation. Dr. Foroud has received personal compensation in the range of $500-$4,999 for serving as a Member of an Advisory Committee with Mayo Clinic, University of Pennsylvania, Allen Institute, Mt. Sinai, Van Andel Institute. |
| Jun Mitsui | No disclosure on file |
| Zbigniew K. Wszolek, MD, FAAN | Dr. Wszolek has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Polish Neurological Society/Via Medica. |
| Stacey Clardy, MD, PhD, FAAN | Dr. Clardy has received personal compensation for serving as an employee of Veterans Health Administration (VHA). Dr. Clardy has received personal compensation for serving as an employee of University of Utah Health. Dr. Clardy has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for AstraZeneca/Alexion. Dr. Clardy has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Amgen/Horizon. Dr. Clardy has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Arialys. Dr. Clardy has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Kyverna. Dr. Clardy has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology/AAN Publications. The institution of Dr. Clardy has received research support from NIH/NINDS. The institution of Dr. Clardy has received research support from SRNA. The institution of Dr. Clardy has received research support from Alexion/AstraZeneca. Dr. Clardy has received personal compensation in the range of $500-$4,999 for serving as a AAN Summer Meeting CoDirector Travel and Lodging with AAN. Dr. Clardy has received personal compensation in the range of $500-$4,999 for serving as a Grand Rounds Travel/Lodging/Honoraria with U of Iowa, Miami, Stanford, Barrow, Beaumont Health, CCF, Emory, Penn State, Mayo Clinic, Walter Reed. |
| Howard I. Hurtig, MD | No disclosure on file |
| Oliver E. Bandmann, MD, PhD, FAAN | No disclosure on file |
| J. T. Greenamyre, MD, PhD | The institution of Dr. Greenamyre has received research support from NIH. The institution of Dr. Greenamyre has received research support from Michael J Fox Foundation. The institution of Dr. Greenamyre has received research support from Calico Life Sciences. The institution of Dr. Greenamyre has received research support from Acurex. |
| John W. Rose, MD, FAAN | The institution of Dr. Rose has received research support from National Multiple Sclerosis Society. The institution of Dr. Rose has received research support from Guthy Jackson Charitable Foundation. The institution of Dr. Rose has received research support from NIH . The institution of Dr. Rose has received research support from VA. The institution of Dr. Rose has received research support from Biogen. The institution of Dr. Rose has received research support from Friends of MS. Dr. Rose has received intellectual property interests from a discovery or technology relating to health care. |
| Lawrence S. Honig, MD, PhD, FAAN | Dr. Honig has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai. Dr. Honig has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Honig has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Medscape. Dr. Honig has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Prevail. Dr. Honig has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Cortexyme. Dr. Honig has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Legal Firms . The institution of Dr. Honig has received research support from Roche. The institution of Dr. Honig has received research support from Eisau. Dr. Honig has received research support from Alector. The institution of Dr. Honig has received research support from Transposon. |
| Ziv Gan-Or, MD, PhD | Dr. Gan-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Neuron23. Dr. Gan-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Idorsia. Dr. Gan-Or has received personal compensation in the range of $0-$499 for serving as a Consultant for Lighthouse. Dr. Gan-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Ono Therapeutics. Dr. Gan-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UCB. Dr. Gan-Or has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Handl Therapeutics. Dr. Gan-Or has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Bial Biotech. |
| Edward Burton | No disclosure on file |
| Alexandra Durr, MD | The institution of Dr. Durr has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UCB. The institution of Dr. Durr has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology Genetics. The institution of Dr. Durr has received research support from NIH. The institution of Dr. Durr has received research support from BIOGEN. The institution of Dr. Durr has received research support from MINORYX. The institution of Dr. Durr has received research support from TRIPLETS THERAPEUTICS. The institution of Dr. Durr has received research support from Servier. The institution of Dr. Durr has received research support from ANR. The institution of Dr. Durr has received research support from PTC. |
| Matthew Padrick, MD | Dr. Padrick has nothing to disclose. |
| Karen Nuytemans, PhD | The institution of Dr. Nuytemans has received research support from NIH. The institution of Dr. Nuytemans has received research support from NIH. The institution of Dr. Nuytemans has received research support from Department of Defense. The institution of Dr. Nuytemans has received research support from Margaret Q. Landenberger Foundation. The institution of Dr. Nuytemans has received research support from American Parkinson Disease Association. The institution of Dr. Nuytemans has received research support from Florida Department of Health. |
| Takashi Matsukawa, MD | No disclosure on file |
| Karen S. Marder, MD, MPH, FAAN | Dr. Marder has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech. Dr. Marder has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Parkinson's Foundation . Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for CHDI. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for PTC therapeutics. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Springer LTD. The institution of Dr. Marder has received research support from Vaccinex. The institution of Dr. Marder has received research support from Genentech. The institution of Dr. Marder has received research support from Triplet Therapeutics. The institution of Dr. Marder has received research support from Prilenia. |
| Jeffery Vance, MD, PhD | Dr. Vance has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for neurology genetics. |
| Margaret A. Pericak-Vance, PhD | Dr. Pericak-Vance has nothing to disclose. |
| Roy Alcalay, MD | Dr. Alcalay has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Genzyme/Sanofi. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Gain Therapeutics. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Vanqua Bio. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Takeda. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biohaven. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Capsida. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Servier. The institution of Dr. Alcalay has received research support from Michael J. Fox Foundation. The institution of Dr. Alcalay has received research support from Parkinson's Foundation. The institution of Dr. Alcalay has received research support from Silverstein Foundation. Dr. Alcalay has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant with Parkinson's Foundation. |
| Sheng-Han Kuo, MD, FAAN | Dr. Kuo has nothing to disclose. |