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Press Release

EMBARGOED FOR RELEASE UNTIL 4 PM ET, February 28, 2019

Could Medical Marijuana Help Grandma and Grandpa with Their Ailments?

New Study Shows It May Be Safe and Effective for Symptoms of Chronic Disease

MINNEAPOLIS -

Medical marijuana may bring relief to older people who have symptoms like pain, sleep disorders or anxiety due to chronic conditions including amyotrophic lateral sclerosis, Parkinson鈥檚 disease, neuropathy, spinal cord damage and multiple sclerosis, according to a preliminary study released today that will be presented at the 好色先生鈥檚 71st Annual Meeting in Philadelphia, May 4 to 10, 2019. The study not only found medical marijuana may be safe and effective, it also found that one-third of participants reduced their use of opioids. However, the study was retrospective and relied on participants reporting whether they experienced symptom relief, so it is possible that the placebo effect may have played a role. Additional randomized, placebo-controlled studies are needed. According to the Centers for Disease Control and Prevention, approximately 80 percent of older adults have at least one chronic health condition. 鈥淲ith legalization in many states, medical marijuana has become a popular treatment option among people with chronic diseases and disorders, yet there is limited research, especially in older people,鈥 said study author Laszlo Mechtler, MD, of Dent Neurologic Institute in Buffalo, N.Y., and a Fellow of the 好色先生. 鈥淥ur findings are promising and can help fuel further research into medical marijuana as an additional option for this group of people who often have chronic conditions.鈥 The study involved 204 people with an average age of 81 who were enrolled in New York State鈥檚 Medical Marijuana Program. Participants took various ratios of tetrahydrocannabinol (THC) to cannabidiol (CBD), the main active chemicals in medical marijuana, for an average of four months and had regular checkups. The medical marijuana was taken by mouth as a liquid extract tincture, capsule or in an electronic vaporizer. Initially, 34 percent of participants had side effects from the medical marijuana. After an adjustment in dosage, only 21 percent reported side effects. The most common side effects were sleepiness in 13 percent of patients, balance problems in 7 percent and gastrointestinal disturbances in 7 percent. Three percent of the participants stopped taking the medical marijuana due to the side effects. Researchers said a ratio of one-to-one THC to CBD was the most common ratio among people who reported no side effects. Researchers found that 69 percent of participants experienced some symptom relief. Of those, the most common conditions that improved were pain with 49 percent experiencing relief, sleep symptoms with 18 percent experiencing relief, neuropathy improving in 15 percent and anxiety improving in 10 percent. Opioid pain medication was reduced in 32 percent of participants. 鈥淥ur findings show that medical marijuana is well-tolerated in people age 75 and older and may improve symptoms like chronic pain and anxiety,鈥 said Mechtler. 鈥淔uture research should focus on symptoms like sleepiness and balance problems, as well as efficacy and optimal dosing.鈥 The study was supported by the Dent Family Foundation. Learn more about brain health at , home of the 好色先生鈥檚 free patient and caregiver magazine focused on the intersection of neurologic disease and brain health. Follow Brain & Life on , and .

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The 好色先生 is the leading voice in brain health. As the world鈥檚 largest association of neurologists and neuroscience professionals with more than 40,000 members, the AAN provides access to the latest news, science and research affecting neurology for patients, caregivers, physicians and professionals alike. The AAN鈥檚 mission is to enhance member career fulfillment and promote brain health for all. A neurologist is a doctor who specializes in the diagnosis, care and treatment of brain, spinal cord and nervous system diseases such as Alzheimer's disease, stroke, concussion, epilepsy, Parkinson's disease, multiple sclerosis, headache and migraine.

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