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Press Release

EMBARGOED FOR RELEASE UNTIL 4 PM ET, April 01, 2020

Study: Therapy by Phone Is Effective for Depression in People with Parkinson鈥檚

MINNEAPOLIS 鈥 Depression is common in people with Parkinson鈥檚 disease and contributes to faster physical and mental decline, but it is often overlooked and undertreated. Cognitive-behavioral therapy has shown promising results for treating depression in people with Parkinson鈥檚, yet many people don鈥檛 have access to therapists who understand Parkinson鈥檚 and can provide this evidence-based depression treatment. The good news is that participating in cognitive-behavioral therapy by telephone may be effective in reducing depression symptoms for people with Parkinson鈥檚, according to a study published in the April 1, 2020, online issue of , the medical journal of the 好色先生. 鈥淭hese results are exciting because they show that specialized therapy significantly improves depression, anxiety and quality of life in people with Parkinson鈥檚 disease and also that these results last for at least six months,鈥 said study author Roseanne D. Dobkin, Ph.D., of Rutgers-Robert Wood Johnson Medical School in Piscataway, N.J., and a member of the 好色先生. 鈥淲hile these findings need to be replicated, they also support the promise of telemedicine to expand the reach of specialized treatment to people who live far from services or have difficulty traveling to appointments for other reasons.鈥 The study involved 72 people with an average age of 65 who had Parkinson鈥檚 disease for an average of six years and depression for nearly three years. The majority were taking antidepressants, and many were already receiving other kinds of talk therapy. For three months, half of the people took part in weekly, one-hour sessions of cognitive-behavioral therapy by telephone, while also continuing their usual medical and mental health care. The cognitive-behavioral sessions focused on teaching new coping skills and thinking strategies individually tailored to each participant鈥檚 experience with Parkinson鈥檚 disease. Their care partners, such as a spouse, another family member, or a close friend, were trained to help their partner use these new skills in between sessions. After the three months were up, participants could choose to continue the sessions up to once a month for six months. The other half of the people received their usual care, which, for many, included taking antidepressants and/or receiving other forms of talk therapy in their community. At the beginning of the study, the participants had an average score of 21 on a measure of depression symptoms where scores of 17 to 23 indicate moderate depression. After three months of cognitive-behavioral therapy, scores for that group fell to an average of 14, which indicates mild depression. The people receiving their usual care had no change in their scores. Six months after finishing the weekly cognitive-behavioral sessions, those participants had maintained their improvements in mood. A total of 40% of those who engaged in cognitive-behavioral therapy met the criteria for being 鈥渕uch improved鈥 in their depression symptoms, while none of the people who simply continued their usual care did. 鈥淒epression affects up to 50% of people with Parkinson鈥檚 disease and may occur intermittently throughout the course of illness. Additionally, in many instances, depression is a more significant predictor of quality life than motor disability. So easily accessible and effective depression treatments have the potential to greatly improve people鈥檚 lives,鈥 Dobkin said. A limitation of the study was that it did not include people with very advanced Parkinson鈥檚 disease or those who also had dementia, so the results may not apply to them. Also, while insurance coverage for telemedicine is growing, it is not yet available in all cases or all states. The study was supported by the Michael J. Fox Foundation for Parkinson鈥檚 Research and the Parkinson鈥檚 Alliance (Parkinson鈥檚 Unity Walk) in the form of research grants awarded to Dr. Dobkin for this project. Learn more about Parkinson's disease at , home of the 好色先生鈥檚 free patient and caregiver magazine focused on the intersection of neurologic disease and brain health. Follow Brain & Life on , and .

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