Abstract Details

Title Timing of EEG in Correlation to Prognosis in Postcardiac Arrest Therapeutic Hypothermia Patients

Topic Epilepsy/Clinical Neurophysiology (EEG)

Presentation(s) S28 - (-)

Poster/Presentation
Number 007

Objective

Background Continuous EEG monitoring has been used for neuroprognostication in patients treated with TH post cardiac arrest. The availability of continuous EEG monitoring for these patients in certain hospitals is limited due to equipment and/or personnel availability.

Design/Methods A retrospective chart review was conducted in patients receiving TH post cardiac arrest over 9 months. EEG results were grouped into favorable or poor prognosis pattern in terms of continuity of background, variability, reactivity, electrographic seizures and periodic discharges. Timing of EEG after cardiac arrest (within 24 hours, 24-48 hours, 48-72 hours, 3-5 days and >5 days), EEG results were correlated with cerebral performance category (CPC) scores on discharge.

Results A total of 36 patients who underwent TH were reviewed. 24/36 (67%) were male and the mean age was 55±15 years old. 93 EEGs were obtained at various time points. Majority of patients had poor prognosis despite of hypothermia (31/36). All EEGs with poor prognostic patterns were correlated with clinical poor outcome (100%) except the EEG performed after 5 days (15/17: 88%). The clinical outcome in relation to EEGs timing was different: 9/12 (75%) EEGs of patients who had poor clinical outcome correlated with malignant patterns within 24 hours after cardiac arrest; 10/10 (100%) between 24-48 hours; 9/10 (90%) for 48-72 hours; 17/19 (89%) between 3-5days; 15/22 (36%) after 5 days. The EEG performed at 24-48 hrs better correlated with clinical prognosis upon discharge among all the groups (p<0.01).

Conclusions EEG performed within 24-48 hours postcardiac arrest had the best correlation with survival and clinic prognosis. EEG performed more than 5 days postcardiac arrest did not correlate well with clinical outcome due to other comorbilities and complications.

Authors/Disclosures
Tapan R. Kavi, MD PRESENTER	No disclosure on file
	No disclosure on file
	No disclosure on file
Melissa A. Carran, MD (Cooper University Med Center)	Dr. Carran has nothing to disclose.
	No disclosure on file
John J. Kelly, Jr., MD	No disclosure on file
Chunyang Wang, MD MS	No disclosure on file

��ɫ��

��ɫ��