Abstract Details

Title Neuro-Developmental Disorders in India - An INCLEN Study

Topic Global Health

Presentation(s) IN6 - (-)

Poster/Presentation
Number 001

Objective

Background The domains studied were: Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorders, Intellectual Disability, Epilepsy, Learning Disability, Neuromuscular Disorders including cerebral palsy, Speech and Language Disorders, and Hearing and Vision Impairment.

Design/Methods A 39 question NDST was developed in English and Hindi, translated into 8 regional languages and validated among 593 subjects in 9 regions of India. The test-retest and inter-rater reliability of the NDST was assessed at two centers in New Delhi, and at the Child Development Center in Thiruvanantapuram, testing 192 children. The test re-test reliability coefficient was above 0.8 for 35 of the 39 questions (89.7%) among both doctors and research assistants. The inter-rater reliability correlation co-efficient was above 0.8 for 21 questions (53.8%). The content validity of the refined tool was then validated in four different strata: rural, urban, hilly areas and tribal areas at five field sites. Conventional clinical diagnostic methods, including expert opinion were used to establish or rule out the presence of NDD's. A total of 593 subjects participated in this piloting.

Results A total of 4,000 households in 6 regions of India were sampled.

Conclusions Subject to extensive ongoing analysis, it appears that 7.5% to 18.5% of children ages 2-9 years suffer from one or more NDD, including those who exhibited more than one NDD. If one excludes isolated hearing impairment, the overall prevalence of NDD's seems to be from 4.7 to 13.7%.

Authors/Disclosures
Donald H. Silberberg, MD, FAAN (Univ of Pennsylvania Medical Center) PRESENTER	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
Sheffali Gulati, MD, FAMS, FIAP, FNASc, FIANs (All India Institute of Medical Sciences)	Prof. Gulati has nothing to disclose.
Pooja Khatri, MD, FAAN (Univ of Cincinnati/Dept of Neuro)	The institution of Dr. Khatri has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Lumosa. Dr. Khatri has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Bayer. The institution of Dr. Khatri has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Diamedica. Dr. Khatri has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Basking Biosciences. Dr. Khatri has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for American Heart Association. The institution of Dr. Khatri has received research support from Cerenovus. Dr. Khatri has received publishing royalties from a publication relating to health care.

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