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2009 Annual Meeting | New Genetics: The Future of Neurology

Friday 05/01/09
09:00 AM - 05:00 PM Add To Calendar
This program will be presented both in-person and online
This program is not expected to be available in the meeting's On Demand product.
Neuroscience Conference
Jeffery Vance, MD, PhD
Participants should be informed about genomic technology and applications known as new genetics.
No CME available
Patient Care & Procedural Skills, Medical Knowledge, Systems-based Practice
Advanced
Practitioner, Fellow, Academician, Resident, Other
Event Timeline
09:00 AM - 09:20 AM Welcome and Introduction
Jeffery Vance, MD, PhD
09:00 AM - 05:00 PM Abstract 001 - OAS1 Genotype Predicts Response to Beta Interferon Therapy in Relapsing Multiple Sclerosis
09:00 AM - 05:00 PM Abstract 001 - A[beta]42 Trimer Gal 4-UAS Gene Vaccine with the Gene Gun To Prevent Alzheimer[apos]s Disease
09:00 AM - 05:00 PM Abstract 002 - Novel Genetic Animal Models of Autism: Molecular Mechanisms to Therapeutic Targets
09:00 AM - 05:00 PM Abstract 003 - Identical Association with Depression in Both Alzheimer and Parkinson Disease
09:00 AM - 05:00 PM Abstract 003 - Uptake and Outcome of Genetic Testing among Participants of the DuchenneConnect Registry
09:00 AM - 05:00 PM Abstract 004 - Reversal of Myotonia and Splicing Defects by Antisense Oligomers in a Transgenic Mouse Model of Myotonic Dystrophy Type 1 (DM1)
09:00 AM - 05:00 PM Abstract 004 - Family History of Melanoma and Parkinson[apos]s Disease Risk
09:00 AM - 05:00 PM Abstract 005 - Genetic Studies on the NNIPPS Cohort: A New Tau Sub-Haplotype in Progressive Supranuclear Palsy
09:00 AM - 05:00 PM Abstract 006 - Transvascular Delivery of siRNAs into the Rat Brain
09:00 AM - 05:00 PM Abstract 007 - A Human Trial of HSV-Mediated Gene Transfer for the Treatment of Chronic Pain
09:00 AM - 05:00 PM Abstract 008 - Candidate Gene Associations and Epistatic Interactions in Cerebrovascular Disease on MRI: The Atherosclerosis Risk in Communities (ARIC) Study
09:00 AM - 05:00 PM Abstract 009 - Gene Expression Levels as Endophenotypes in Genome-Wide Association Studies To Identify Susceptibility Variants for Late-Onset Alzheimer[apos]s Disease
09:00 AM - 05:00 PM Abstract 010 - Meta-Analysis of Genome Scans and Replication Identify [italic]CD6[/italic], [italic]ICSBP1[/italic], and [italic]TNFRSF1A[/italic] as Novel Multiple Sclerosis Susceptibility Loci
09:20 AM - 09:55 AM History of Genetics
Kenneth H. Fischbeck, MD, FAAN
09:55 AM - 10:30 AM Genetics 101: Clinical
Thomas D. Bird, MD, FAAN
10:30 AM - 11:05 AM Genetics 101: Technical/Toys
Stephan Zuchner, MD, FAAN
11:05 AM - 11:25 AM Break
11:55 AM - 12:30 PM Epigenetics
Massimo Pandolfo, MD, FAAN
12:30 PM - 01:30 PM Luncheon
01:30 PM - 02:05 PM Regulatory Systems
Derek Dykxhoorn, PhD
02:35 PM - 03:10 PM Complex Genetics: Multiple Sclerosis
Jonathan Haines, MD
03:10 PM - 03:30 PM Break
03:30 PM - 04:05 PM Complex Genetics: Autism
Margaret A. Pericak-Vance, PhD
04:05 PM - 04:40 PM Personalized Medicine
Jeffery Vance, MD, PhD
04:40 PM - 05:00 PM Questions and Answers
Faculty Disclosures
Thomas D. Bird, MD, FAAN Dr. Bird has nothing to disclose.
David J. Fink, MD, FAAN No disclosure on file
Kenneth H. Fischbeck, MD, FAAN Dr. Fischbeck has received research support from NINDS/NIH. Dr. Fischbeck has received intellectual property interests from a discovery or technology relating to health care. Dr. Fischbeck has a non-compensated relationship as a Scientific Review Board member with Kennedy's Disease Association that is relevant to AAN interests or activities. Dr. Fischbeck has a non-compensated relationship as a Scientific Council member with Association Francaise contre les Myopathies that is relevant to AAN interests or activities. Dr. Fischbeck has a non-compensated relationship as a Independent Review Committee member with Target ALS that is relevant to AAN interests or activities. Dr. Fischbeck has a non-compensated relationship as a Scientific Advisory Board member, Musculoskeletal Diseases with Novartis that is relevant to AAN interests or activities. Dr. Fischbeck has a non-compensated relationship as a Senior Clinical Consultant with n-Lorem Foundation that is relevant to AAN interests or activities. Dr. Fischbeck has a non-compensated relationship as a Scientific Advisory Committee member with Stanford GNE myopathy program that is relevant to AAN interests or activities. Dr. Fischbeck has a non-compensated relationship as a Scientific Advisory Board member with Hereditary Disease Foundation that is relevant to AAN interests or activities. Dr. Fischbeck has a non-compensated relationship as a Scientific Advisory Board member with Packard Center for ALS Research that is relevant to AAN interests or activities. Dr. Fischbeck has a non-compensated relationship as a Scientific Advisory Board member with Huntington's Disease Society of America that is relevant to AAN interests or activities. Dr. Fischbeck has a non-compensated relationship as a TACT review panel member with TREAT-NMD that is relevant to AAN interests or activities.
Neill R. Graff-Radford, MD, FAAN The institution of Dr. Graff-Radford has received research support from Biogen. The institution of Dr. Graff-Radford has received research support from Lilly. The institution of Dr. Graff-Radford has received research support from Eisai. The institution of Dr. Graff-Radford has received research support from Biogen. Dr. Graff-Radford has received publishing royalties from a publication relating to health care.
David A. Hafler, MD, FAAN Dr. Hafler has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Biogen. Dr. Hafler has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Genetech. Dr. Hafler has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Roche. Dr. Hafler has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Joint Commission International.
Stephen L. Hauser, MD Dr. Hauser has received personal compensation in the range of $500-$4,999 for serving as a Consultant for NGM Bio. Dr. Hauser has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Moderna. Dr. Hauser has received personal compensation in the range of $500-$4,999 for serving as a Consultant for BD. Dr. Hauser has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Pheno Therapeutics. Dr. Hauser has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Nurix Therapeutics. Dr. Hauser has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Gilead. Dr. Hauser has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Accure. Dr. Hauser has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alector. Dr. Hauser has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Annexon. Dr. Hauser has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Hinge Therapeutics. Dr. Hauser has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Neurona. Dr. Hauser has a non-compensated relationship as a Clinical Trial/Primary Investigator with Roche that is relevant to AAN interests or activities. Dr. Hauser has a non-compensated relationship as a Clinical Trial/Primary Investigator with Novartis that is relevant to AAN interests or activities.
David S. Knopman, MD, FAAN Dr. Knopman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for DIAN TU study. The institution of Dr. Knopman has received research support from NIH.
Ronald C. Petersen, MD, PhD, FAAN Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genentech. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly and Co.. Dr. Petersen has received personal compensation in the range of $0-$499 for serving as a Consultant for Eisai, Inc.. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novo Nordisk. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Petersen has received publishing royalties from a publication relating to health care. Dr. Petersen has received publishing royalties from a publication relating to health care. Dr. Petersen has received publishing royalties from a publication relating to health care. Dr. Petersen has a non-compensated relationship as a Board of Directors with American Brain Foundation that is relevant to AAN interests or activities.
Denis J. Petro, MD No disclosure on file
Stefan M. Pulst, MD, FAAN Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for venrock. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Arrowhead. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Leverna. Dr. Pulst has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AAN. Dr. Pulst has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Leninthal LLC. The institution of Dr. Pulst has received research support from NINDS. Dr. Pulst has received intellectual property interests from a discovery or technology relating to health care.
Roger N. Rosenberg, MD, FAAN No disclosure on file
Giovanna M. Spinella, MD No disclosure on file
Charles A. Thornton, MD, FAAN Dr. Thornton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Avidity. Dr. Thornton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Thornton has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Ionis. Dr. Thornton has received personal compensation in the range of $50,000-$99,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Dyne. Dr. Thornton has received personal compensation in the range of $50,000-$99,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Pepgen. The institution of Dr. Thornton has received research support from Marigold Foundation. The institution of Dr. Thornton has received research support from NIH. The institution of Dr. Thornton has received research support from Muscular Dystrophy Association . The institution of Dr. Thornton has received research support from Dyne. The institution of Dr. Thornton has received research support from Avidity. The institution of Dr. Thornton has received research support from Ionis. Dr. Thornton has received intellectual property interests from a discovery or technology relating to health care.
Jeffery Vance, MD, PhD Dr. Vance has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for neurology genetics.
Yves Agid, MD, PhD No disclosure on file
Massimo Pandolfo, MD, FAAN Dr. Pandolfo has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Design Therapeutics . Dr. Pandolfo has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Biogen. Dr. Pandolfo has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Solid Bio. Dr. Pandolfo has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Neurocrine. Dr. Pandolfo has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Design Therapeutics. Dr. Pandolfo has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Larimar. Dr. Pandolfo has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology Genetics. Dr. Pandolfo has stock in Voyager Therapeutics. The institution of Dr. Pandolfo has received research support from Freidreich Ataxaia Research Alliance. Dr. Pandolfo has a non-compensated relationship as a Scientific Advisory Board with Friedreich Ataxia Research Alliance that is relevant to AAN interests or activities. Dr. Pandolfo has a non-compensated relationship as a Member-Meeting Management Committee with AAN that is relevant to AAN interests or activities.
Albert C. Ludolph, MD Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Ludolph has received personal compensation in the range of $0-$499 for serving as a Consultant for FundaMental Pharma . Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Lilly. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Zambon . Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche Pharma. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alector. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Amylyx. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Biologix FZCo.. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Biogen. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Teva. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Biogen. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Biogen. Dr. Ludolph has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Zambon.
Margaret A. Pericak-Vance, PhD Dr. Pericak-Vance has nothing to disclose.
Peter N. Leigh, BSc, MB, FAAN No disclosure on file
Dennis W. Dickson, MD Dr. Dickson has nothing to disclose.
Michael Schwarzschild, MD, PhD The institution of Dr. Schwarzschild has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Bial Biotech (indirectly, as a service of the Parkinson Study Group service). The institution of Dr. Schwarzschild has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen (indirectly, as a service of the Parkinson Study Group service). The institution of Dr. Schwarzschild has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for UCB (indirectly, as a service of the Parkinson Study Group service). Dr. Schwarzschild has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eli Lilly. The institution of Dr. Schwarzschild has received research support from NIH. The institution of Dr. Schwarzschild has received research support from Parkinson's Foundation. The institution of Dr. Schwarzschild has received research support from Michael J Fox Foundation. The institution of Dr. Schwarzschild has received research support from Farmer Family Foundation. Dr. Schwarzschild has a non-compensated relationship as a Chair, Executive Committee with the Parkinson Study Group that is relevant to AAN interests or activities.
Duong Huynh, PhD No disclosure on file
Jorge Oksenberg, MD No disclosure on file
Gilbert Bensimon, MD No disclosure on file
Omar M. Wazzan, MD No disclosure on file
Alexis Brice, MD Dr. Brice has received personal compensation in the range of $100,000-$499,999 for serving as an officer or member of the Board of Directors for ICM.
Iscia Lopes-Cendes, MD, PhD No disclosure on file
Steven G. Younkin, MD, PhD No disclosure on file
Jonathan Haines, MD No disclosure on file
Nicholas W. Wood No disclosure on file
No disclosure on file
Marina Mata, MD No disclosure on file
Karen E. Morrison, PhD, FRCP No disclosure on file
Alexandra Durr, MD The institution of Dr. Durr has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UCB. The institution of Dr. Durr has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology Genetics. The institution of Dr. Durr has received research support from NIH. The institution of Dr. Durr has received research support from BIOGEN. The institution of Dr. Durr has received research support from MINORYX. The institution of Dr. Durr has received research support from TRIPLETS THERAPEUTICS. The institution of Dr. Durr has received research support from Servier. The institution of Dr. Durr has received research support from ANR. The institution of Dr. Durr has received research support from PTC.
Craig M. Powell, MD, PhD, FAAN No disclosure on file
Philip De Jager, MD, PhD Dr. De Jager has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Biogen. Dr. De Jager has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Puretech. Dr. De Jager has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for roche. Dr. De Jager has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for biogen. The institution of Dr. De Jager has received research support from roche. The institution of Dr. De Jager has received research support from Biogen. The institution of Dr. De Jager has received research support from puretech.
Alberto Ascherio, MD, PhD The institution of Dr. Ascherio has received research support from NIH and US Department of Defense .
Thomas H. Mosley, PhD No disclosure on file
Stephan Zuchner, MD, FAAN Dr. Zuchner has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Applied Therapeutics. The institution of Dr. Zuchner has received research support from Muscular Dystrophy Association. The institution of Dr. Zuchner has received research support from CMT Association. Dr. Zuchner has received intellectual property interests from a discovery or technology relating to health care.
Nilufer Taner, MD, PhD, FAAN The institution of Dr. Taner has received research support from NIH.
Michael Hutchinson, MD Dr. Hutchinson has nothing to disclose.
Minerva Carrasquillo Minerva Carrasquillo has nothing to disclose.
Myriam Fornage No disclosure on file
Alastair Compston, PhD, FRCP No disclosure on file
Kelly Claire Simon, ScD No disclosure on file
Niall Tubridy, MD Dr. Tubridy has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis .
Laura Coker, PhD No disclosure on file
Xiang Gao, MD, PhD Dr. Gao has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Nutrition Journal. The institution of Dr. Gao has received research support from NIH.
Baoxi Qu No disclosure on file
Gaofeng Wang No disclosure on file
Roisin Lonergan, MD No disclosure on file
Geraldine Hipp No disclosure on file
Margaret A. O'Brien, MD No disclosure on file
gs Gurjeet Singh, MD No disclosure on file
William K. Scott, MD No disclosure on file
Derek Dykxhoorn, PhD No disclosure on file
Mark R. Etherton, MD Dr. Etherton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for WorldCare Clinical. Dr. Etherton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for AstraZeneca. Dr. Etherton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Clarion Healthcare. Dr. Etherton has received research support from 好色先生. Dr. Etherton has received research support from MGH Executive Council on Research. Dr. Etherton has received research support from NINDS. Dr. Etherton has received publishing royalties from a publication relating to health care.
Michael A. Slifer No disclosure on file
Thomas C. Sudhof No disclosure on file
Darren P. Wolfe, PhD No disclosure on file
Michael H. Parkinson, MD No disclosure on file
Stephen Sawcer, PhD No disclosure on file
Gary W. Beecham, PhD The institution of Dr. Beecham has received research support from NIH. The institution of an immediate family member of Dr. Beecham has received research support from NIH.
Manal A. Badawi, MD Dr. Badawi has nothing to disclose.
Jared Cook No disclosure on file
Mark P. Fitzgerald, MD, PhD Dr. Fitzgerald has nothing to disclose.
Naomi Kouri No disclosure on file
Beverly Snively The institution of Beverly Snively has received research support from National Institutes of Health. The institution of Beverly Snively has received research support from Duke Endowment. The institution of Beverly Snively has received research support from Department of Defense. The institution of Beverly Snively has received research support from PCORI.
Galen Joe No disclosure on file