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2013 Annual Meeting | S50 - Multiple Sclerosis: Novel Mechanisms of Action

Thursday 03/21/13
12:00 PM - 01:45 PM Add To Calendar
This program will be presented both in-person and online
This program is not expected to be available in the meeting's On Demand product.
Scientific Platform Session
MS and Related Diseases
No CME available
Event Timeline
12:00 PM - 01:45 PM Abstract 001 - Identification of a Unique Microglial Signature in Mice and Humans
Oleg Butovsky, PhD
12:00 PM - 01:45 PM Abstract 002 - Aiolos Silences Il2 Expression and Promotes Th17 Cell Differentiation
Francisco J. Quintana, PhD
12:00 PM - 01:45 PM Abstract 003 - High Dietary Salt Aggravates Experimental Neuroinflammation in Mice Via Induction of Th17 Cells
Ralf Linker
12:00 PM - 01:45 PM Abstract 004 - microRNA as a Therapeutic Target in Multiple Sclerosis
Marcin P. Mycko, MD
12:00 PM - 01:45 PM Abstract 005 - Regulation of Human CNS Myeloid Cell Inflammatory Responses by mir-155
Craig S. Moore, PhD
12:00 PM - 01:45 PM Abstract 006 - Upregulation of Glucocorticoid-Induced Leucine Zipper by Hepatocyte Growth Factor Promotes Tolerogenic Dendritic Cells and Inhibits Experimental Autoimmune Encephalomyelitis
Nicolas Molnarfi
12:00 PM - 01:45 PM Abstract 007 - Contribution of an Anti-Neuronal Immune Response to Neurodegeneration in Multiple Sclerosis
Michael C. Levin, MD, FAAN
Faculty Disclosures
Silva Markovic-Plese, MD, FAAN Dr. Markovic-Plese has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi. Dr. Markovic-Plese has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Sanofi.
Michael K. Racke, MD Dr. Racke has received personal compensation for serving as an employee of Quest Diagnostics. Dr. Racke has stock in Quest Diagnostics. Dr. Racke has received intellectual property interests from a discovery or technology relating to health care.
Marie-Laure Santiago-Raber, PhD No disclosure on file
Nicolas Molnarfi No disclosure on file
David H. Margolin, MD, PhD Dr. Margolin has received personal compensation for serving as an employee of Cerevance, Inc. Dr. Margolin has received personal compensation in the range of $0-$499 for serving as a Consultant for Datacubed Health. Dr. Margolin has received stock or an ownership interest from Cerevance, Inc. Dr. Margolin has received stock or an ownership interest from Datacubed Health. Dr. Margolin has received intellectual property interests from a discovery or technology relating to health care.
No disclosure on file
Patrice LaLive, MD Dr. LaLive has nothing to disclose.
Jack P. Antel, MD, FAAN Dr. Antel has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for sanofi, roche, biogen, wave,nervgen. The institution of Dr. Antel has received research support from Novartis canada bristol myers squib. Dr. Antel has a non-compensated relationship as a past president with ACTRIMS that is relevant to AAN interests or activities.
Oleg Butovsky, PhD No disclosure on file
Francisco J. Quintana, PhD Dr. Quintana has nothing to disclose.
Lidia Gardner, PhD, EMBA Dr. Gardner has stock in EMD Serono.
Benjamin M. Segal, MD Dr. Segal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Bloom, Inc. Dr. Segal has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eli Lily. The institution of Dr. Segal has received research support from NIH. Dr. Segal has received intellectual property interests from a discovery or technology relating to health care. Dr. Segal has received intellectual property interests from a discovery or technology relating to health care. Dr. Segal has received personal compensation in the range of $5,000-$9,999 for serving as a Expert talks moderator; writer/ commentator with Ology Medical 好色先生, Inc/ Neurodiem.
Craig S. Moore, PhD Dr. Moore has nothing to disclose.
Howard L. Weiner, MD Dr. Weiner has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genentech. Dr. Weiner has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Medday Pharmaceuticals. Dr. Weiner has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for vTv Therapeutics. Dr. Weiner has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Tiziana Life Sciences. Dr. Weiner has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for vTv Therapeutics. Dr. Weiner has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Medday Pharmaceuticals. Dr. Weiner has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for vTv Therapeutics. Dr. Weiner has stock in vTv Therapeutics. The institution of Dr. Weiner has received research support from National Institute of Health. The institution of Dr. Weiner has received research support from National MS Society. The institution of Dr. Weiner has received research support from Genzyme Corp. The institution of Dr. Weiner has received research support from Genentech, Inc. . The institution of Dr. Weiner has received research support from Verily Life Sciences LLC. The institution of Dr. Weiner has received research support from EMD Serono, Inc..
Amit Bar-Or, MD, FRCPC Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche Genentech. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Merk/EMD Serono. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sanofi-Genzyme. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for cabaletta. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche/Genentech. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Merck/EMD Serono. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi/Genzyme. The institution of Dr. Bar-Or has received research support from Novartis. The institution of Dr. Bar-Or has received research support from Biogen. The institution of Dr. Bar-Or has received research support from Roche/Genentech.
David A. Hafler, MD, FAAN Dr. Hafler has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Biogen. Dr. Hafler has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Genetech. Dr. Hafler has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Roche. Dr. Hafler has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Joint Commission International.
Manu Rangachari, PhD No disclosure on file
Ada Yeste No disclosure on file
Ralf Linker Dr. Linker has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Linker has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Springer. The institution of Dr. Linker has received research support from Novartis. The institution of Dr. Linker has received research support from Biogen.
Marcin P. Mycko, MD No disclosure on file
Michael C. Levin, MD, FAAN Dr. Levin has received personal compensation for serving as an employee of Merck. Dr. Levin has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. The institution of Dr. Levin has received research support from CIHR.
Beata Sliwinska No disclosure on file
Vijay K. Kuchroo, PhD, DVM Vijay Kuchroo has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Tizona. Vijay Kuchroo has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Equillium. Vijay Kuchroo has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Pfizer. Vijay Kuchroo has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Pfizer. Vijay Kuchroo has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Viela Bio. Vijay Kuchroo has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Kintai. Vijay Kuchroo has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Astellas. Vijay Kuchroo has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Equillium. Vijay Kuchroo has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Repertoir. Vijay Kuchroo has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Cellsius. Vijay Kuchroo has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for Genentech. Vijay Kuchroo has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Bicara. Vijay Kuchroo has received personal compensation in the range of $50,000-$99,999 for serving as an officer or member of the Board of Directors for Biocon Biologic. Vijay Kuchroo has received personal compensation in the range of $50,000-$99,999 for serving as an officer or member of the Board of Directors for Syngene. Vijay Kuchroo has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for McNeill Baur. Vijay Kuchroo has received stock or an ownership interest from Bicara. Vijay Kuchroo has received stock or an ownership interest from Biocon Biologic. Vijay Kuchroo has received stock or an ownership interest from Biolegend. Vijay Kuchroo has received stock or an ownership interest from Celsius. Vijay Kuchroo has received stock or an ownership interest from Equillium. Vijay Kuchroo has received stock or an ownership interest from Syngene. Vijay Kuchroo has received stock or an ownership interest from Tizona. Vijay Kuchroo has received stock or an ownership interest from Alpine Immune Sciences. The institution of Vijay Kuchroo has received research support from Lupus Research Alliance . The institution of Vijay Kuchroo has received research support from F. Hoffmann-LaRoche Ltd.. The institution of Vijay Kuchroo has received research support from Sanofi/Genzyme . The institution of Vijay Kuchroo has received research support from Nancy Davis Innovation Award . The institution of Vijay Kuchroo has received research support from NIH. Vijay Kuchroo has received intellectual property interests from a discovery or technology relating to health care.
Vijayaraghava T. Rao, PhD No disclosure on file
Samuel Ludwin, MD No disclosure on file
Krzysztof W. Selmaj Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving as a Consultant for BMS. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Astra. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Merck. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for BMS. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Astra. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Biogen. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Roche. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Novartis. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for BMS. Krzysztof W. Selmaj has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Merck.