Abstract Details

Title EEG-Based Typing Interface with Language Model for Individuals Who Are Functionally Locked-In

Topic Neural Repair/Rehabilitation

Presentation(s) S14 - (-)

Poster/Presentation
Number 004

Objective

Background Locked-in syndrome (LIS) is a rare condition; we use a definition of functional LIS, a more common condition, to describe individuals who cannot rely on speech and/or writing for consistent reliable communication due to severe disabilities. To begin to address the communication needs of individuals with functional LIS, we have developed and tested a system that can eventually be used in individuals with complete LIS.

Design/Methods The RSVP KeyboardTM was developed with several unique features. Individual symbols, including 26 letters, backspace and space, are presented using rapid serial visual presentation (RSVP) at 2.5 per sec. Computer classification of letters as targets or non-targets based on EEG is performed using machine learning that incorporates a language model for letter prediction via Bayesian fusion. User-centered design is accomplished by the inclusion of people with FLIS in all stages of research & development.

Results There were 6 participants with functional LIS, mean age 45.5, mean education level 15.5 years, who were tested in their residences, and 11 healthy controls. Each participant first calibrated the system, and then completed a series of letter generation tasks that were designed with 5 incremental levels of difficulty, that increased by selecting phrases for which the utility of the language model decreased naturally. All functional LIS subjects successfully completed at least level 1 of this RSVP KeyboardTM, and 1 subject achieved level 5. Six of 11 control subjects achieved level 5.

Conclusions Functionally locked-in individuals may benefit from an EEG-based BCI interface using RSVP and incorporating a language model. Steps to further improve the system will be discussed.

Authors/Disclosures
Barry S. Oken, MD, PhD, FAAN (Oregon Health & Science Univ.) PRESENTER	Dr. Oken has nothing to disclose.
	No disclosure on file
	No disclosure on file
Thomas C. Chelimsky, MD (Medical College of Wisconsin)	Dr. Chelimsky has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Proctor & Gamble. Dr. Chelimsky has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Various Legal Firms. Dr. Chelimsky has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Various Legal Firms. Dr. Chelimsky has received stock or an ownership interest from PainSTakers, LLC. The institution of Dr. Chelimsky has received research support from NIDDK. The institution of Dr. Chelimsky has received research support from Advancing a Healthier Wisconsin.
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file

��ɫ��

��ɫ��