Abstract Details

Title Risk of Brain Infarctions during Carotid Endarterectomy and Stenting - Pilot Data of a Prospective Study

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) S22 - (-)

Poster/Presentation
Number 003

Objective

Background Silent infarctions can be detected in ?30% of patients after carotid endarterectomy (CEA) and in ?54% of patients after carotid stenting (CAS).

Design/Methods All consecutive patients 1/ with ICA stenosis >70%, 2/ indicated to carotid intervention, 3/ without contraindications to CEA or CAS, 4/ who signed informed consent, were enrolled to the study during 23 months. Patients were indicated to CEA or CAS according to the European Stroke Organization guidelines. Only patients eligible for both methods were enrolled to the study and randomly allocated to CEA or CAS. Neurological examination and brain magnetic resonance imaging (MRI) were performed before and 24 h after intervention in all patients. Occurrence of new brain infarctions was statistically evaluated using T-test.

Results Totally 105 patients were included into the study. Fifty-two patients (35 males, mean age 62.8 ± 7.6 years) underwent CEA and 53 patients (42 males, mean age 67.7 ± 8.0 years) underwent CAS. New brain infarctions on control MRI were found in 12 (23.1%) patients in CEA group (only in the territory of the intervened artery) and in 25 (47.2%) patients CAS group (in 13 cases in both hemispheres) (P=0.005). Brain infarction was symptomatic in only 1 patient in both groups (P>0.05).

Conclusions Study results confirm higher risk of the occurrence of silent brain infarctions on MRI during CAS in comparison with CEA.

Authors/Disclosures
PRESENTER	No disclosure on file
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David Skoloudik, MD, PhD (University Hospital Ostrava)	No disclosure on file
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