Abstract Details

Title Callosal Disconnection and Limb-Kinetic Apraxia

Topic Behavioral Neurology

Presentation(s) P06 - (-)

Poster/Presentation
Number 073

Objective

Background BACKGROUND: According to Liepmann, patients with limb kinetic apraxia have a loss of upper limb deftness-dexterity. Several studies have revealed in right handers that, whereas injury of the left hemisphere induces an ipsilesional LKA, injury to the right hemisphere does not induce an ipsilesional LKA. There are at least two possible means by which the left hemisphere may influence the deftness of the left hand, either by callosal connections or by ipsilesional corticospinal projections.

Design/Methods DESIGN/METHODS: Careful clinical examination of a patient with a septum pellucidum cyst status post surgical intervention revealed a limb-kinetic and motor apraxia.

Results RESULTS: This 57 year old right handed man had a memory impairment and upon brain imaging was found to have a septum pellucidum cyst, which was causing mild obstruction to the occipital and temporal horns. He underwent an endoscopic-assisted fenestration of the septum pellucidum. Postoperative imaging revealed a lesion of the mesial portion of his corpus callosum and assessment of praxis revealed he had both a limb-kinetic and ideomotor apraxia of his left but not his right hand.

Conclusions CONCLUSIONS: The observation that this man had a callosal disconnection limb-kinetic apraxia of his left hand suggest that in some people it is the left hemisphere's premotor or motor cortex that provides information to the right hemisphere's motor system about the programs needed to make deft movements.

Authors/Disclosures
Lealani M. Acosta, MD, MPH, FAAN (Vanderbilt University Medical Center) PRESENTER	Dr. Acosta has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Alector. Dr. Acosta has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology. The institution of Dr. Acosta has received research support from AbbVie, Sage, NIH, Bristol Myers Squibb/Fortrea, CND Life Sciences.
	No disclosure on file
Kenneth M. Heilman, MD, FAAN (Univ. of Florida, Dept. of Neurology)	Dr. Heilman has received publishing royalties from a publication relating to health care.
Antonios Bayas	No disclosure on file

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