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Abstract Details

Comparison of ABC/2 with a Simplified ABC/2 Formula in Calculating Intracerebral Hemorrhage Volume
Cerebrovascular Disease and Interventional Neurology
P06 - (-)
252
BACKGROUND: ABC/2 has been correlated with clinical outcomes. In ABC/2, C is the number of approximate cuts the ICH is seen (weighted by area as < 25%, 25-50%, or > 75%). In clinical and research use, the original ABC/2 has been simplified (sABC/2) where C is the total number of cuts the ICH is seen. In the simplied form, each cut is weighted the same. ABC/2 has been validated as a reliable bedside method of measuring ICH volume, but sABC/2 has not been studied.
DESIGN/METHODS: With IRB approval, we retrospectively reviewed consecutive spontaneous acute ICH patients admitted to our institution from November 1, 2009 to April 30, 2010. We excluded pure intraventricular hemorrhage (IVH), subarachnoid hemorrhage, traumatic ICH, or multifocal ICH. CT brain was reviewed by an attending vascular neurologist or neurointensivist. Data was collected on CT measurements of ICH and ICH volume was calculated using both methods.
RESULTS: Among 81 patients with ICH, the location was deep in 40 (49.4%), lobar in 29 (35.8%), and infratentorial in 12 (14.8%). Thirty eight patients (46.9%) had IVH. The mean volume of ICH with ABC2 was 12.5 cc (range 0.377 to 71.54) and with sABC/2 was 27.8 cc (range 0.26 to 154.2). The mean difference in volumes between ABC/2 and sABC/2 was 15.3 cc (SD + 23.6). The differences between the volume by sABC/2 and ABC/2 increased with larger ICH volumes, with the equation of the regression line as follows: sABC/2 = -0.25 + 2.3 ABC/2 (p < 0.0001).
CONCLUSIONS: sABC/2 does not accurately measure volume of ICH when compared to ABC2, and the differences between the methods increases with larger ICH volumes. Clinicians should be aware of the limitations of sABC/2.
Authors/Disclosures
Vivien H. Lee, MD, FAAN (OSU Comprehensive Neurovascular Center)
PRESENTER 		Dr. Lee has nothing to disclose.
Sarah Song, MD, MPH, FAAN (Rush University Medical Center) Dr. Song has received personal compensation in the range of $50,000-$99,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AAN.
Shawna M. Cutting, MD, FAAN The institution of Dr. Cutting has received research support from Genentech.
Katharina M. Busl, MD, MS, FAAN (University of Florida) Dr. Busl has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Rissman Law. Dr. Busl has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Huffman Powell Baley. Dr. Busl has received personal compensation in the range of $500-$4,999 for serving as a Consultant for University Science. Dr. Busl has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for SCCM. Dr. Busl has a non-compensated relationship as a Board Member with Art in Medicine that is relevant to AAN interests or activities. Dr. Busl has a non-compensated relationship as a Associate Editor with Critical Care Explorations that is relevant to AAN interests or activities. Dr. Busl has a non-compensated relationship as a Assistant Editor with Neurocritical Care that is relevant to AAN interests or activities.
James Conners, MD (Rush University Medical Center) The institution of Dr. Conners has received research support from nih.
Rajeev Garg, MD, FAAN (Rush University Medical Center) Dr. Garg has nothing to disclose.
Douglas L. Arnold, MD, FAAN (Montreal Neurological Institute, McGill Univ) Dr. Arnold has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Biogen. Dr. Arnold has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for BMS. Dr. Arnold has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Frequency Therapeutics. Dr. Arnold has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Merck. Dr. Arnold has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Novartis. Dr. Arnold has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Roche. Dr. Arnold has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Sanofi. Dr. Arnold has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Shionogi. Dr. Arnold has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Xfacto communications. Dr. Arnold has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly. Dr. Arnold has received personal compensation in the range of $500-$4,999 for serving as a Consultant for EMD Serono. Dr. Arnold has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biohaven. Dr. Arnold has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Find therapeutics. Dr. Arnold has received personal compensation in the range of $500-$4,999 for serving as a Consultant for GSK. Dr. Arnold has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Idorsia. Dr. Arnold has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Kiniksa. Dr. Arnold has received personal compensation in the range of $100,000-$499,999 for serving as a Consultant for Clario.