Abstract Details

Title The Face of Migraine; Thermal Imaging Revisited

Topic Headache

Presentation(s) P06 - (-)

Poster/Presentation
Number 154

Objective

Background BACKGROUND: Evidence suggests specific thermographic patterns can be seen during a migraine headache attack and normalize interictally. Such findings, however, have not been uniform.

Design/Methods DESIGN/METHODS: We prospectively collected facial videos using a thermal camera (FLIR systems, FLIR SC 4000, Boston, MA, USA) from eight migraine patients during two different sessions: symptomatic ("Migraine") and asymptomatic ("Baseline"). Each recording lasted approximately 5 minutes. All patients had episodic migraine with or without aura per ICHD-2. Patients taking daily preventive medications and those with chronic migraine were excluded. Because we have two tests (supraorbital thermal signal and periorbital thermal signal) we used the Bonferroni correction for the level of significance (?c=0.05/2=0.025).

Results RESULTS: Every subject had a significantly higher mean supraorbital temperature in the baseline session compared to the migraine session. In the two-sample t-test for each subject, the mean supraorbital response variable had significant differences between the baseline and migraine sessions, all p-values were far less than ?c=0.025. In 7 out of 8 subjects the baseline session had a significantly higher mean periorbital temperature compared to the migraine session. In one subject there was no significant difference. In the two-sample t-test for each subject, the mean periorbital response variable had significant differences between the baseline and migraine sessions, all the p-values but one were far less than ?c=0.025.

Conclusions CONCLUSIONS: In this study, a characteristic facial thermal signature (supraorbital and periorbital cooling) identifies migraine headache attack presence. The mechanisms behind this thermophysiologic response require further study. We envision this thermal signature may help convey migraine presence in patients who can't verbally communicate. In verbal patients, the thermal signature may allow identification and treatment of unsuspected migraine headache attacks early in their course before full development.

Authors/Disclosures
Ivan Garza, MD, FAAN (Mayo Clinic) PRESENTER	No disclosure on file
Daniel Ontaneda, MD, PhD, FAAN (Cleveland Clinic)	Dr. Ontaneda has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Ontaneda has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genentech/Roche. Dr. Ontaneda has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen Idec. Dr. Ontaneda has received personal compensation in the range of $500-$4,999 for serving as a Consultant for BMS. Dr. Ontaneda has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sanofi. The institution of Dr. Ontaneda has received research support from NIH. The institution of Dr. Ontaneda has received research support from PCORI. The institution of Dr. Ontaneda has received research support from NMSS. The institution of Dr. Ontaneda has received research support from Genetech.
	No disclosure on file
	No disclosure on file
	No disclosure on file
Jerry W. Swanson, MD, FAAN	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file

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