Abstract Details

Title Multisensor System as a Clinical Aid in Evaluation Differentiation of Tremor Disorders

Topic Movement Disorders

Presentation(s) P06 - (-)

Poster/Presentation
Number 100

Objective

Background BACKGROUND: Currently, the differention of the etiology of tremor disorders is a challenging task for most specialists. In the case of Essential (ET) and Parkinsonian tremor (PT), this is specially difficult in several instances. From a physiological standpoint, these tremors have their own characteristics, however the measurement of these parameters are not part of routine clinical practice.

Design/Methods DESIGN/METHODS: The system sensors (accelerometers) were placed in eight body parts of interest in lower and upper limbs, positioning the measuring axes perpendicular to the longitudinal axis of the limb. Registration assessed the limbs at rest, as well as with postural and kinetic tests. Analyses were focused in function of the specific features of each disease and also the signals for their RMS amplitude and frequency.

Results RESULTS: A total of 17 patients with ET (6 men, mean age 62 years) and 62 with PT (30 men, mean age 65.3 years) wer analysed. Cases of PT presented with a mean frequency of 5.3Hz at rest, 5.8Hz with posture and 6.5Hz kinetic (average for the 3 tests 5.8Hz). Cases of ET have an average tremor frequency of 6Hz at rest, 6.2Hz with posture and 6.5Hz kinetic (average for the tests 6.2Hz). The RMS amplitude of tremor allowed division of cases with PT into 3 groups, group 1 with the closest characteristics of classical PT and group 3 with characteristics very similar to those of ET.

Conclusions CONCLUSIONS: Our system was able to differentiate ET and PT in regards to frequency. In addition, the system allowed us to analyze amplitude parameters, identifying cases in which there was a significant overlap between both forms of tremor.

Authors/Disclosures
Helio Afonso G. Teive, MD, PhD, FAAN PRESENTER	Dr. Teive has nothing to disclose.
Renato P. Munhoz, MD, PhD	Dr. Munhoz has nothing to disclose.
	No disclosure on file
	No disclosure on file
	No disclosure on file
Ronald C. Petersen, MD, PhD, FAAN (Mayo Clinic)	Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genentech. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly and Co.. Dr. Petersen has received personal compensation in the range of $0-$499 for serving as a Consultant for Eisai, Inc.. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novo Nordisk. Dr. Petersen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Petersen has received publishing royalties from a publication relating to health care. Dr. Petersen has received publishing royalties from a publication relating to health care. Dr. Petersen has received publishing royalties from a publication relating to health care. Dr. Petersen has a non-compensated relationship as a Board of Directors with American Brain Foundation that is relevant to AAN interests or activities.

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