Abstract Details

Title Post-COVID-19 Cognitive Impairment: A Case-control Study

Topic Aging, Dementia, and Behavioral Neurology

Presentation(s) P8 - Poster Session 8 (5:30 PM-6:30 PM)

Poster/Presentation
Number 9-001

Objective The goal of our study was to analyze the frequency and the determinants of cognitive impairment and other associated neurological impairment among COVID-19 recovered cases four weeks after being diagnosed with COVID-19 during the fourth wave of the pandemic

Background The fight against Coronavirus disease 2019 (COVID-19) appears to extend beyond screening and treatment of acute diseases due to its medium and long-term health consequences. Post-COVID-19 associated cognitive impairment affects the quality of life of millions of persons and implies a significant global economic burden . Furthermore, there are currently no specific treatments available.

Design/Methods A case-control study targeted 176 post-COVID cases and 92 age and sex matched healthy controls who met the selection criteria from three Arabic countries (Algeria, Egypt, and Libya). A well-trained physician performed the investigation using a structured and validated questionnaire.

Results The post-COVID-19 cases exhibit statistically significant cognitive deficits, chronic fatigue, and impairment of the senses of appetite, taste, smell, and hearing. Among the 19 post-COVID cases, the frequency of post-COVID-19 cognitive impairment is 57(32.3%) with a statistically significant higher mean age (44.6±16.9) (P<0.001) and statistically higher consumption of junk food (8.6±3.3) (P=0.04). The cognitive impairment was significantly higher among females (83.3%), non-smokers (57.9%), highly educated (76.5%), and married (63.7%).

Conclusions COVID-19 infection significantly increases the frequency of cognitive impairment, and neurological symptoms (smell and taste disability, chronic fatigability, and appetite disturbance) compared to a matched control. Cognitive impairment after COVID-19 is more intensive in older people, females, unemployed, smokers, having higher education, and eaters of unhealthy food.

Authors/Disclosures
Ahmed Negida, MD, PhD (Virginia Commonwealth University) PRESENTER	Dr. Negida has nothing to disclose.
Mohamed Elsayed	No disclosure on file
Samar Ahmed Amer	Samar Ahmed Amer has nothing to disclose.
Mahmoud T. Hefnawy, MD (Zagazig University Faculty Of Medicine)	Dr. Hefnawy has nothing to disclose.
Ines Djelleb	No disclosure on file
Ehab Ishteiwy	No disclosure on file
Mostafa M. Meshref, MD (Al-Azhar University, Cairo)	Dr. Meshref has nothing to disclose.
Youmna Amer	No disclosure on file
Jaffer Shah	No disclosure on file
Eman AbdelFattah	No disclosure on file
Noha Hashim	No disclosure on file
Carlos Schönfeldt-Lecuona	No disclosure on file

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