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Abstract Details

Caroticocavernous Fistulae: A Real World Comparison of Clinicoradiographic Features and Treatment Approaches
Cerebrovascular Disease and Interventional Neurology
P10 - Poster Session 10 (11:45 AM-12:45 PM)
5-007
This study aimed to describe the clinical outcomes in a cohort of caroticocavernous fistulae (CCF) patients and identify clinical and angiographic features differentiating patients more likely to benefit from endovascular intervention.
 CCFs are a rare subtype of intracranial arteriovenous fistulae with variable clinical and angiographic presentations that make treatment selection challenging.

A single-center, retrospective analysis was performed to identify all patients with angiographically-confirmed CCF between 2000 and 2022. Pertinent data, including clinical symptoms, angiographic findings, treatment strategies, recurrence rates, and complications, were collected.

A total of 84 patients were included, of whom 67 (80%) underwent endovascular intervention and 17 (20%) were conservatively managed. Primary endovascular techniques were transvenous coil embolization (78%), feeder artery embolization (16%), and ICA flow diversion (8%). High-risk clinical symptoms, such as reduced visual acuity (53% of intervention vs 6% of conservative, p=<0.0001), and angiographic features, such as cortical (39% vs 0%, p=0.002) and ophthalmic venous reflux (91% vs 69%, p=0.034), were more common in the intervention group. All direct (Barrow Type A) CCFs underwent endovascular intervention (32% vs 0%, p=0.005), while indirect (Barrow types B-D) CCFs were common in the conservatively managed group (68% of intervention vs 100% of conservative, p=0.005). 31% of treated CCFs required retreatment, which primarily occurred with Barrow type D CCFs and following transvenous coil embolization as the initial treatment method. Procedure-related complications occurred in 10% of cases and consisted of cranial nerve palsies (n=5), asymptomatic dissection (n=1), and asymptomatic distal thromboembolic event (n=1).

High-risk symptoms and angiographic features favor endovascular intervention. Various embolization techniques, including transvenous coil embolization, proved safe and effective; complications were rare and mostly transient. In select CCF patients without high-risk clinical or angiographic features, conservative observation was a safe and effective alternative to endovascular embolization. Longitudinal angiographic surveillance is essential for monitoring fistula persistence or recurrence.
Authors/Disclosures
Justin Vranic (Massachusetts General Hospital)
PRESENTER
No disclosure on file
Robert W. Regenhardt, MD, PhD Dr. Regenhardt has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genomadix. Dr. Regenhardt has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Rapid Medical. Dr. Regenhardt has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Johnson and Bell Trial Lawyers. Dr. Regenhardt has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Buckley, Theroux, Kline, & Cooley Trial Lawyers. The institution of Dr. Regenhardt has received research support from National Institutes of Health. The institution of Dr. Regenhardt has received research support from Society of Vascular and Interventional Neurology. The institution of Dr. Regenhardt has received research support from Heitman Foundation.
Amine Mohamed Marc Awad, BM BCh Dr. Awad has nothing to disclose.
James Rabinov James Rabinov has nothing to disclose.