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2026 Annual Meeting | N4 - Neuroscience in the Clinic: Waves of Change in Neurology: Rethinking Cortical Spreading Depolarization (CSD)

Tuesday 04/21/26
01:00 PM - 03:00 PM CDT Add To Calendar
This program will be presented both in-person and online
This program will be available in the meeting's On Demand product.
Neuroscience in the Clinic Session
Rashmi B. Halker Singh, MD, FAAN, Sarah E. Nelson, MD, MPH, FAAN
General Neurology
Cortical spreading depolarization (CSD) is gaining momentum as a key mechanism in neuroscience, with growing relevance across a range of neurologic conditions—including migraine, subarachnoid hemorrhage, and beyond. This session brings together leading scientists and clinicians to explore the pathophysiology of CSD and its emerging clinical implications. Attendees will gain insights into how CSD may influence patient care across diverse neurologic populations, and what it could mean for future management strategies.
2.00 CME credits
Medical Knowledge, Practice-based Learning and Improvement, Quality Improvement
Intermediate
Fellow, Resident, General Neurologist, Specialist Neurologist, Advanced Practice Provider, Neurohospitalist, Medical Student
Case-based, Didactic
Event Timeline
01:00 PM - 01:05 PM CDT Introduction Introduction
Rashmi B. Halker Singh, MD, FAAN
01:05 PM - 01:20 PM CDT Speaker Clinical Case
Sarah E. Nelson, MD, MPH, FAAN
01:20 PM - 01:45 PM CDT Speaker Spreading Depolarization: Brain Death versus Reboot
Jens P. Dreier, MD
01:45 PM - 01:55 PM CDT Speaker Abstract Presentation #1
01:55 PM - 02:20 PM CDT Speaker The Role of Cortical Spreading Depolarization in Stroke and Seizures
David Y. Chung, MD
02:20 PM - 02:30 PM CDT Speaker Abstract Presentation #2
02:30 PM - 03:00 PM CDT Q&A Panel Discussion
Rashmi B. Halker Singh, MD, FAAN, Sarah E. Nelson, MD, MPH, FAAN, Jens P. Dreier, MD, David Y. Chung, MD
Faculty Disclosures
Rashmi B. Halker Singh, MD, FAAN Dr. Halker Singh has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Pfizer. Dr. Halker Singh has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for AbbVie. Dr. Halker Singh has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Lundbeck. Dr. Halker Singh has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Current Neurology & Neuroscience Reports. Dr. Halker Singh has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Headache Journal. Dr. Halker Singh has received publishing royalties from a publication relating to health care. Dr. Halker Singh has received personal compensation in the range of $5,000-$9,999 for serving as a CME speaker with Pri-med. Dr. Halker Singh has received personal compensation in the range of $500-$4,999 for serving as a CME speaker with Medscape.
Sarah E. Nelson, MD, MPH, FAAN Dr. Nelson has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology Journal. Dr. Nelson has received publishing royalties from a publication relating to health care. Dr. Nelson has a non-compensated relationship as a Women Leading in Neurology Program with 好色先生 that is relevant to AAN interests or activities.
Jens P. Dreier, MD Prof. Dreier has nothing to disclose.
David Y. Chung, MD The institution of Dr. Chung has received research support from NIH/NINDS. The institution of Dr. Chung has received research support from Brain Aneurysm Foundation. The institution of Dr. Chung has received research support from Angea Biotherapeutics.