2026 Annual Meeting | C170 - The Tired Brain: Approaches to Fatigue Across Neurology

Date Wednesday 04/22/26

Time 07:00 AM - 09:00 AM CDT Add To Calendar

Session Format This program will be presented both in-person and online

On Demand This program will be available in the meeting's On Demand product.

Event Type Seminar

Director(s) Joyce K. Lee-Iannotti, MD, FAAN

Topic(s) Sleep

Learning Objectives By the end of this course, participants will be able to: Differentiate fatigue from sleepiness, apathy, and depression in neurology patients. Recognize the prevalence, clinical features, and impact of fatigue across key neurological disorders (MS, Parkinson’s, stroke, epilepsy, neuromuscular disease, long COVID). Apply a structured approach to evaluating fatigue, including relevant history, examination, screening tools, and laboratory/ancillary testing. Implement evidence-based management strategies (pharmacologic and non-pharmacologic), with emphasis on sleep medicine principles, exercise, cognitive-behavioral strategies, and treatment of comorbidities. Engage in case-based discussions that highlight practical pearls and pitfalls in addressing fatigue across diverse neuro clinics

CME Available 2.00 CME credits

Core Competencies Patient Care & Procedural Skills, Interpersonal and Communication Skills, Professionalism, Medical Knowledge, Practice-based Learning and Improvement, Systems-based Practice, Quality Improvement

Recommended Audience Fellow, Resident, General Neurologist, Specialist Neurologist, Non-neurologist, Advanced Practice Provider, Neurohospitalist, Medical Student

Event Timeline
07:00 AM - 07:10 AM CDT	Introduction	Framing Fatigue in Neurology: Definitions, Epidemiology, Impact
07:10 AM - 07:25 AM CDT	Speaker	Clinical Differentiation: Fatigue vs Sleepiness vs Depression vs Apathy (Sleep Neurology Perspective)
07:25 AM - 07:40 AM CDT	Speaker	Fatigue in Specific Disorders: MS and Neuroimmunology
07:40 AM - 07:55 AM CDT	Speaker	Fatigue in Specific Disorders: Movement Disorders (Parkinson’s and Beyond)
07:55 AM - 08:10 AM CDT	Speaker	Fatigue in Specific Disorders: Epilepsy, Stroke, Neuromuscular Disorders
08:10 AM - 08:25 AM CDT	Speaker	Post-COVID and Post-Infectious Fatigue: Special Focus
08:25 AM - 08:50 AM CDT	Discussion	Interactive Case Discussions and Q&A
08:50 AM - 09:00 AM CDT	Closing Remarks	Wrap-Up and Take-Home Clinical Algorithm

Faculty Disclosures
Joyce K. Lee-Iannotti, MD, FAAN	Dr. Lee-Iannotti has nothing to disclose.
Karin G. Johnson, MD, FAAN	Dr. Johnson has received personal compensation in the range of $0-$499 for serving as an officer or member of the Board of Directors for Save Standard Time. The institution of Dr. Johnson has received research support from Apnimed.
Margaret A. Kay-Stacey, MD	Dr. Kay-Stacey has received personal compensation in the range of $0-$499 for serving as a Expert Panelist (one time event) with AAN NeuroPanels .

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