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2018 Annual Meeting | S3 - Movement Disorders: Parkinson's Disease: Genetics, Biomarkers, and Diagnosis

Sunday 04/22/18
01:00 PM - 03:00 PM Add To Calendar
This program will be presented both in-person and online
This program is not expected to be available in the meeting's On Demand product.
Scientific Platform Session
Movement Disorders
2.00 CME credits
Event Timeline
01:00 PM - 03:00 PM Abstract 001 - Validation of the MDS Clinical Diagnostic Criteria for Parkinson's Disease
Ronald Postuma, MD
01:00 PM - 03:00 PM Abstract 002 - Application of the Movement Disorder Society Prodromal Criteria in healthy G2019S-LRRK2 carriers
Anat Mirelman
01:00 PM - 03:00 PM Abstract 003 - Features of GBA-associated Parkinson's disease at presentation in the United Kingdom Tracking Parkinson's study
Naveed Malek, MD
01:00 PM - 03:00 PM Abstract 004 - Genetic risk variants for Parkinson's disease (PD) and cognitive impairment in four clinical PD subtypes
Angela B. Deutschlander, MD
01:00 PM - 03:00 PM Abstract 005 - Nilotinib significantly alters CSF biomarkers and increases endogenous dopamine in open-label phase I clinical trial in Parkinson's disease with dementia and Lewy body dementia
Fernando L. Pagan, MD, FAAN
01:00 PM - 03:00 PM Abstract 006 - Tear Proteins as Possible Biomarkers for Parkinson's Disease
01:00 PM - 03:00 PM Abstract 007 - Automatic Detection of ON/OFF states in Parkinson Disease Patients Using Wearable Sensor Technology
01:00 PM - 03:00 PM Abstract 008 - Glucose dysregulation in Parkinson's disease: a controlled cross-sectional study
Ana Marques
02:35 PM - 03:00 PM Discussion Discussion
Faculty Disclosures
Irene Litvan, MD, FAAN Dr. Litvan has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Aprinoia. Dr. Litvan has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Lundbeck. Dr. Litvan has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Frontiers in Neurology. Dr. Litvan has received personal compensation in the range of $50,000-$99,999 for serving as a Chief Editor with Frontiers in Neurology.
Roy Alcalay, MD Dr. Alcalay has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Genzyme/Sanofi. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Gain Therapeutics. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Vanqua Bio. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Takeda. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biohaven. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Capsida. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Servier. The institution of Dr. Alcalay has received research support from Michael J. Fox Foundation. The institution of Dr. Alcalay has received research support from Parkinson's Foundation. The institution of Dr. Alcalay has received research support from Silverstein Foundation. Dr. Alcalay has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant with Parkinson's Foundation.
Jennifer R. Friedman, MD An immediate family member of Dr. Friedman has received personal compensation in the range of $0-$499 for serving as a Consultant for Sinopia Biosciences. An immediate family member of Dr. Friedman has received personal compensation in the range of $0-$499 for serving as an officer or member of the Board of Directors for Pet Dx. Dr. Friedman has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for MedLink Neurology. Dr. Friedman has stock in Friedman Bioventure .
Raja Mehanna, MD Dr. Mehanna has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Teva. Dr. Mehanna has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Kyowa Kirin. The institution of Dr. Mehanna has received research support from Cerevel. The institution of Dr. Mehanna has received research support from Neurocrine.
Anthony E. Lang, MD, FAAN Dr. Lang has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for AbbVie, Amylyx, Aprinoia, Biogen, BioAdvance, Biohaven, BioVie, BlueRock, BMS, Denali, Janssen, Lilly, Pharma 2B, Sun Pharma, and UCB. Dr. Lang has received personal compensation in the range of $50,000-$99,999 for serving as an Expert Witness for medicolegal cases related to paraquat. The institution of Dr. Lang has received research support from AbbVie. Dr. Lang has received intellectual property interests from a discovery or technology relating to health care. Dr. Lang has received publishing royalties from a publication relating to health care.
Christopher Goetz, MD, FAAN The institution of Dr. Goetz has received research support from Michael J. Fox Foundation. The institution of Dr. Goetz has received research support from NIH. The institution of Dr. Goetz has received research support from Department of Defense. Dr. Goetz has received publishing royalties from a publication relating to health care. Dr. Goetz has received publishing royalties from a publication relating to health care. Dr. Goetz has received publishing royalties from a publication relating to health care.
Silvia J. Rios Romenets, MD Dr. Rios Romenets has nothing to disclose.
Ronald Postuma, MD Dr. Postuma has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Roche, Biogen, Takeda, Theranexus, GE, Jazz, Curasen, Paladin, Inception Sciences, Phytopharmics, Vaxxinity, Merck. Dr. Postuma has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen/Partners. The institution of Dr. Postuma has received research support from CIHR, Weston Foundation, Webster Foundation, Roche, MJFF, Parkinson Canada, FRSQ, NIH.
No disclosure on file
Michael Erb No disclosure on file
Julia Rybkina No disclosure on file
Bryan K. Ho, MD No disclosure on file
Susan B. Bressman, MD, FAAN The institution of Dr. Bressman has received research support from Michael J Fox Foundation . The institution of Dr. Bressman has received research support from NIH .
Karen S. Marder, MD, MPH, FAAN Dr. Marder has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech. Dr. Marder has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Parkinson's Foundation . Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for CHDI. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for PTC therapeutics. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Springer LTD. The institution of Dr. Marder has received research support from Vaccinex. The institution of Dr. Marder has received research support from Genentech. The institution of Dr. Marder has received research support from Triplet Therapeutics. The institution of Dr. Marder has received research support from Prilenia.
Laurie J. Ozelius, PhD The institution of Dr. Ozelius has received research support from NIH. Dr. Ozelius has received intellectual property interests from a discovery or technology relating to health care.
Elizabeth E. Mundel, MD No disclosure on file
James N. Starr, DO No disclosure on file
Abigail C. Lawler, MD No disclosure on file
Nadia Yusuf, MD No disclosure on file
Fernando L. Pagan, MD, FAAN Dr. Pagan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Acorda. Dr. Pagan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Adamas. Dr. Pagan has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Amneal. Dr. Pagan has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Merz. Dr. Pagan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Kyowa Kirin. Dr. Pagan has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Sunovion. Dr. Pagan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Teva. Dr. Pagan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for US World Meds. Dr. Pagan has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Supernus. Dr. Pagan has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Abbvie. Dr. Pagan has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Acorda. Dr. Pagan has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Adamas. Dr. Pagan has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Amneal. Dr. Pagan has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Sunovion. Dr. Pagan has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Teva. Dr. Pagan has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Neurocrine. Dr. Pagan has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Sunovion. Dr. Pagan has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Supernus. Dr. Pagan has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Journal of Clinical Parkinsonism and related Disorders. Dr. Pagan has stock in Keiferx. The institution of Dr. Pagan has received research support from US World Meds. The institution of Dr. Pagan has received research support from Novartis.
Ian Bledsoe, MD Dr. Bledsoe has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Destum Partners. Dr. Bledsoe has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Abbvie Inc. Dr. Bledsoe has received personal compensation in the range of $0-$499 for serving as a Consultant for Clarity.Co. The institution of Dr. Bledsoe has received research support from Dystonia Medical Research Foundation. The institution of Dr. Bledsoe has received research support from NIH. The institution of Dr. Bledsoe has received research support from Michael J Fox Foundation.
Paul Wacnik No disclosure on file
Nicholas W. Wood No disclosure on file
Angela B. Deutschlander, MD No disclosure on file
David J. Burn, MD No disclosure on file
Roger Barker, PhD Roger Barker, PhD has nothing to disclose.
Piu Chan, MD, PhD No disclosure on file
Zbigniew K. Wszolek, MD, FAAN Dr. Wszolek has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Polish Neurological Society/Via Medica.
Rachel J. Saunders-Pullman, MD The institution of Dr. Saunders-Pullman has received research support from NIH, Bigglesworth Family Foundation, Empire Clinical Research Investigatory Program.
Ana Marques No disclosure on file
Elizabeth Slow, MD, PhD Dr. Slow has nothing to disclose.
Mark F. Lew, MD, FAAN Dr. Lew has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Supernus. Dr. Lew has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for kyowa. Dr. Lew has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for neurocrine. Dr. Lew has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Acorda. Dr. Lew has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Acadia. Dr. Lew has received personal compensation in the range of $500-$4,999 for serving as a Consultant for RegenXBio. Dr. Lew has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Neurocrine. Dr. Lew has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Kyowa. Dr. Lew has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for acorda. The institution of Dr. Lew has received research support from MJFF. Dr. Lew has received research support from NIH.
Werner Poewe, MD Werner Poewe, MD has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Affiris . Werner Poewe, MD has received personal compensation in the range of $50,000-$99,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alterity, AbbVie, BIAL, Biogen, Britannia, Lilly, Lundbeck, Neuroderm, Neurocrine, Denali Pharmaceuticals, ,Roche, Takeda, UCB and Zambon . Werner Poewe, MD has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for AbbVie, Britannia, BIAL, STADA, Lundbeck, Zambon. The institution of Werner Poewe, MD has received research support from MJFF; EU Horizon programme. Werner Poewe, MD has a non-compensated relationship as a Committee member with Movement Disorder Society that is relevant to AAN interests or activities.
Klaus Seppi, MD Dr. Seppi has received personal compensation in the range of $500-$4,999 for serving as a Consultant for ONO . Dr. Seppi has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Lundbeck. Dr. Seppi has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for BIAL. Dr. Seppi has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for AbbVie. Dr. Seppi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Novartis. Dr. Seppi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Roche. Dr. Seppi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Bial. Dr. Seppi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Teva. The institution of Dr. Seppi has received research support from MJFF. The institution of Dr. Seppi has received research support from EU. The institution of Dr. Seppi has received research support from FWF Austrian Science Fund,.
Franck Durif, MD, PhD No disclosure on file
Glenda Halliday No disclosure on file
Wendy Mack No disclosure on file
Hao Zhang, PhD No disclosure on file
Vesper F. Ramos, MD No disclosure on file
Charbel E. Moussa, PhD, MB Dr. Moussa has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for KeifeRX LLC. Dr. Moussa has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sun Pharmaceuticals Research Industry. Dr. Moussa has received stock or an ownership interest from Orphan Therapeutics. The institution of Dr. Moussa has received research support from NIA. The institution of Dr. Moussa has received research support from Sun Pharmaceuticals Research Industry. The institution of Dr. Moussa has received research support from Alzheimer's Association . Dr. Moussa has received intellectual property interests from a discovery or technology relating to health care. Dr. Moussa has received intellectual property interests from a discovery or technology relating to health care. Dr. Moussa has received publishing royalties from a publication relating to health care. Dr. Moussa has received personal compensation in the range of $500-$4,999 for serving as a Grant reviewer with DG Information Technology. Dr. Moussa has received personal compensation in the range of $0-$499 for serving as a Peer Reviews with National Institutes of Health.
Nin Bajaj, MD No disclosure on file
Huw R. Morris, MD, PhD Dr. Morris has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Dr. Morris has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Aprinoia. Dr. Morris has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. Dr. Morris has received personal compensation in the range of $50,000-$99,999 for serving as an Expert Witness for Personal injury / Negligence cases. The institution of Dr. Morris has received research support from Parkinson's UK. The institution of Dr. Morris has received research support from Michael J Fox Foundartion. The institution of Dr. Morris has received research support from Cure Parkinson's Trust. The institution of Dr. Morris has received research support from PSP Association. The institution of Dr. Morris has received research support from CBD Solutions. The institution of Dr. Morris has received research support from Drake Foundation. The institution of Dr. Morris has received research support from Medical Research Council. Dr. Morris has received intellectual property interests from a discovery or technology relating to health care. Dr. Morris has a non-compensated relationship as a Scientific Advisory Board with Cure PSP that is relevant to AAN interests or activities. Dr. Morris has a non-compensated relationship as a Scientific Advisory Board with Parkinson's UK that is relevant to AAN interests or activities.
Katherine Grosset No disclosure on file
Anat Mirelman Anat Mirelman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Abbvie . Anat Mirelman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Bial. The institution of Anat Mirelman has received research support from Department of Defense. The institution of Anat Mirelman has received research support from MJFF. The institution of Anat Mirelman has received research support from JPND. The institution of Anat Mirelman has received research support from EU-Horizon 2020.
Nir Giladi, MD, FAAN Dr. Giladi has received personal compensation in the range of $0-$499 for serving as a Consultant for Sionara. Dr. Giladi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for NeuroDerm. Dr. Giladi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Pharma2B. Dr. Giladi has stock in Vibrant. Dr. Giladi has stock in Lysosomal Therapeutics . The institution of Dr. Giladi has received research support from The Michael J Fox Foundation. The institution of Dr. Giladi has received research support from The National Parkinson Foundation. The institution of Dr. Giladi has received research support from The European Union . The institution of Dr. Giladi has received research support from The Israel Science Foundation. The institution of Dr. Giladi has received research support from Biogen . The institution of Dr. Giladi has received research support from Ionis. The institution of Dr. Giladi has received research support from Sieratzki Family Foundation . The institution of Dr. Giladi has received research support from The Aufzien Academic Center in Tel-Aviv University.
Deborah Raymond The institution of Ms. Raymond has received research support from NIH.
Avner Thaler, MD The institution of Dr. Thaler has received personal compensation in the range of $500-$4,999 for serving as a Consultant for ABBVIE. The institution of Dr. Thaler has received research support from MJFF.
Lorraine N. Clark, PhD No disclosure on file
Yasar A. Torres-Yaghi, MD Dr. Torres-Yaghi has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Acorda. Dr. Torres-Yaghi has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Abbvie. Dr. Torres-Yaghi has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Amneal. Dr. Torres-Yaghi has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Abbott. Dr. Torres-Yaghi has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Kyowa Kirin. Dr. Torres-Yaghi has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Teva. Dr. Torres-Yaghi has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Sunovion .
Melissa Naylor Ms. Naylor has received personal compensation for serving as an employee of Takeda. Ms. Naylor has stock in Takeda.
Takuya Konno, MD, PhD No disclosure on file
Naveed Malek, MD Dr. Malek has nothing to disclose.
Ryan J. Uitti, MD, FAAN Dr. Uitti has nothing to disclose.
Owen A. Ross, PhD Dr. Ross has nothing to disclose.
Audrey Strongosky No disclosure on file
Donald Grosset Donald Grosset has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Glasgow Memory Clinic. Donald Grosset has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for IQVIA. Donald Grosset has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for AbbVie. Donald Grosset has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Britannia. Donald Grosset has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for GE Healthcare. The institution of Donald Grosset has received research support from Parkinson's UK. Donald Grosset has received personal compensation in the range of $10,000-$49,999 for serving as a Clinical Director Excellence Network with Parkinson's UK.
Jay A. Van Gerpen, MD, FAAN No disclosure on file