EMBARGOED FOR RELEASE UNTIL 4 PM ET, January 25, 2012
Study: Men at Higher Risk for Mild Memory Loss Than Women
ST. PAUL, Minn. -
Men may be at higher risk of experiencing mild cognitive impairment (MCI), or the stage of mild memory loss that occurs between normal aging and , than women, according to a study published in the January 25, 2012, online issue of the medical journal of the 好色先生. 鈥淭hese results are surprising, given that women generally have higher rates of dementia than men,鈥 said study author R.O. (Rosebud) Roberts, MB ChB, MS, of the Mayo Clinic in Rochester, Minn., and a member of the 好色先生. 鈥淭he risk of MCI in men and women combined was high in this age group of elderly persons. This is disturbing given that people are living longer, and MCI may have a large impact on health care costs if increased efforts at prevention are not used to reduce the risk.鈥 For the study, a group of 1,450 people from Olmsted County, Minn., between the ages of 70 and 89 and free of dementia at enrollment underwent memory testing every 15 months for an average of three years. Participants were also interviewed about their memory by medical professionals. By the end of the study period, 296 people had developed MCI. The study found that the number of new cases of MCI per year was higher in men, at 72 per 1,000 people compared to 57 per 1,000 people in women and 64 per 1,000 people in men and women combined. MCI with memory loss present was more common at 38 per 1,000 people than MCI where memory loss was not present, which affected 15 per 1,000 people. Those who had less education or were not married also had higher rates of MCI. 鈥淥ur study suggests that risk factors for mild cognitive impairment should be studied separately in men and women,鈥 said Roberts. Another finding of interest in the study showed that among people who were newly diagnosed with MCI, 12 percent per year were later diagnosed at least once with no MCI, or reverted back to what was considered 鈥渃ognitively normal.鈥 Roberts said the majority of people with MCI, about 88 percent per year, continue to have MCI or progress to dementia. The study was supported by the National Institutes of Health, the Robert Wood Johnson Foundation, the Robert H. and Clarice Smith and Abigail van Buren Alzheimer鈥檚 Disease Research Program and was made possible by the Rochester Epidemiology Project.