EMBARGOED FOR RELEASE UNTIL 4 PM ET, June 15, 2016
Having a Relative with Epilepsy May Increase Your Risk of Being Diagnosed with Autism
MINNEAPOLIS -
Having a first-degree relative with epilepsy may increase a person鈥檚 risk of being diagnosed with autism, according to a study published in the June 15, 2016, online issue of , the medical journal of the 好色先生. 鈥淥ther studies have linked the two conditions, however, our study looks specifically at the brothers and sisters and sons and daughters of people with epilepsy to determine a possible autism risk in these relatives,鈥 said study author Hel茅ne E.K. Sundelin, MD, with University Hospital in Link枚ping, Sweden. For the study, researchers looked at a data registry and identified 85,201 people with epilepsy, as well as all of their siblings (80,511 people) and offspring (98,534 people). Each person with epilepsy was compared with five people without epilepsy of similar age, sex and from the same county during the same period. The siblings and offspring of those with epilepsy were also compared with siblings and offspring of people without epilepsy. Siblings and offspring who had epilepsy were excluded from the research. During the average six-year follow-up period of the study, 1,381 of participants with epilepsy and 700 of the people without epilepsy were diagnosed with autism. People with epilepsy were therefore at increased risk of being diagnosed with autism (1.6 percent compared to 0.2 percent), with the highest risk seen in those diagnosed with epilepsy in childhood (5.2 percent). The study found a 63 percent increased risk of developing autism for siblings and offspring even when the person with epilepsy was excluded. Offspring of mothers had a 91 percent increased risk and offspring of fathers had a 38 percent increased risk. 鈥淭he goal is to find out more about how these two diseases may be linked so that treatments may be developed that will target both conditions,鈥 said Sundelin. The study was supported by the Swedish Research Council, the Swedish Initiative for Research on Microdata in the Social and Medical Sciences, the Swedish Research Council for Health, Working Life and Welfare, the Swedish Research Council and the Stockholm County Council. To learn more about autism and epilepsy, please visit .