EMBARGOED FOR RELEASE UNTIL 4 PM ET, October 27, 2021
Study: Death Rate from Parkinson鈥檚 Rising in U.S.
MINNEAPOLIS -A new study shows that in the last two decades the death rate from Parkinson鈥檚 disease has risen about 63% in the United States. The research is published in the October 27, 2021, online issue of , the medical journal of the 好色先生. The study also found that the death rate was twice as high in men as in women, and there was a higher death rate in white people than other racial/ethnic groups. 鈥淲e know that people are living longer and the general population is getting older, but that doesn鈥檛 fully explain the increase we saw in the death rate in people with Parkinson鈥檚,鈥 study author Wei Bao, MD, PhD, who conducted the research at the University of Iowa in Iowa City. 鈥淯nderstanding why more people are dying from this disease is critical if we are going to reverse the trend.鈥 The study looked at a national death registry that included 479,059 people who died of Parkinson鈥檚 between 1999 and 2019. After adjusting for age, researchers found that the number of people who died from the disease increased from 5.4 per 100,000 people in 1999 to 8.8 per 100,000 people in 2019. The average annual increase was 2.4%. Researchers found mortality increased significantly across all age groups, both sexes, various racial and ethnic groups and different urban-rural classifications. However, death rates were twice as high in men as in women. Bao says one possible explanation for this sex difference is that estrogen, which leads to higher dopamine levels in parts of the brain that control motor responses, may protect women from developing Parkinson鈥檚. White people were more likely to die from Parkinson鈥檚 than other racial and ethnic groups. In 2019, the death rate for white people was 9.7 per 100,000 people, followed by Hispanic people, at 6.5 per 100,000 people, and non-Hispanic Black people, at 4.7 per 100,000 people. Bao said previous studies have shown that compared to white people, Black and Hispanic people are less likely to see an outpatient neurologist, due to socioeconomic barriers, suggesting that white people may have a higher chance of receiving a Parkinson鈥檚 diagnosis. 鈥淚t鈥檚 important to continue to evaluate long-term trends in Parkinson鈥檚 death rates,鈥 Bao said. 鈥淭his can inform future research that may help pinpoint why more people are dying of the disease. Also, updating vital statistics about Parkinson鈥檚 death rates may be used for priority setting and financing of health care and policy.鈥 A limitation of the study is that only one underlying cause of death was recorded on each death certificate, so only people who were recorded as having died of Parkinson鈥檚 were included in the study. This may not accurately reflect the prevalence of the disease as a cause of death. Learn more about Parkinson鈥檚 disease at , home of the 好色先生鈥檚 free patient and caregiver magazine focused on the intersection of neurologic disease and brain health. Follow Brain & Life庐 on , and . When posting to social media channels about this research, we encourage you to use the hashtags #Neurology and #AANscience.