EMBARGOED FOR RELEASE UNTIL 4 PM ET, February 16, 2022
How Long Does It Really Take to Recover from Concussion?
Study Suggests Thinking and Memory Problems Common One Year Later
MINNEAPOLIS - A new study suggests that people with mild traumatic brain injuries may be more likely to have cognitive impairment, cognitive decline or both one year later, compared to people who were not injured. The research is published in the February 16, 2022, online issue of , the medical journal of the 好色先生. People with poor cognitive outcomes were also more likely to have other symptoms like anxiety and lower satisfaction with life. 鈥淥ur results suggest that clinically meaningful poor cognitive outcomes, which we defined as cognitive impairment, cognitive decline or both, one year after a concussion may be more common than previously thought,鈥 said study author Raquel Gardner, MD, of the University of California San Francisco. 鈥淭hey also highlight the need to better understand the mechanisms underlying poor cognitive outcome, even after relatively mild brain injuries, to improve therapy for recovery.鈥 The study looked at 656 people who had been admitted to trauma center emergency rooms with concussions and 156 healthy people without head injuries. Their average age was 40. Participants were given up to three neurological evaluations after their injury, at two weeks, six months and one year. Each of those evaluations provided five scores from three tests of recall, language skills and other cognitive domains. Poor cognitive outcome was defined as satisfying the criteria for cognitive impairment, cognitive decline or both. Cognitive impairment was defined as lower-than-expected performance on at least two cognitive tests such as one memory test and one processing speed test. Cognitive decline was defined as clinically meaningful decline on at least two cognitive tests. Researchers found that 86 out of 656 people with mild brain injuries, or 14%, had poor cognitive outcomes one year later. Of those, 10% had cognitive impairment only, 2% had cognitive decline only and 2% had both. That鈥檚 compared to eight out of 156 people without concussions, or 5%, who had poor cognitive outcomes one year later. Of those healthy people, 3% had cognitive impairment, none had cognitive decline only, and 1% had both. Researchers also found that people who had depression before their injury, had no health insurance, or had a high school education or less were more likely to have a poor cognitive outcome than those who were not depressed before the injury, or had insurance or had more than a high school education. Researchers found that people who had good cognitive outcomes were more likely to have higher life satisfaction one year after their concussion. The life satisfaction test given to participants ranges in score from five to 35, with lower scores indicating lower life satisfaction. The people with good cognitive outcomes scored an average of 26 on the test, compared to people with poor cognitive outcomes, who scored an average of 21. The study does not prove that people with concussions will have worse cognitive outcomes one year later, but it shows an association. 鈥淧revious studies of people with moderate to severe brain injuries show that early, intensive rehabilitation can improve people鈥檚 cognitive outcomes over time. More research is needed to find out the role of cognitive rehabilitation on people with more mild brain injuries who are also at risk for poor cognitive outcomes, and how to predict who falls into this risk category,鈥 Gardner said. A limitation of the study is that people were enrolled at the time of their concussion and their cognitive health before injury was not known. The study was supported by the National Institutes of Health, National Institute of Neurological Disorders and Stroke and the Department of Defense. Learn more about concussion at , home of the 好色先生鈥檚 free patient and caregiver magazine focused on the intersection of neurologic disease and brain health. Follow Brain & Life庐 on , and . When posting to social media channels about this research, we encourage you to use the hashtags #Neurology and #AANscience.