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Press Release

EMBARGOED FOR RELEASE UNTIL 4 PM ET, November 16, 2022

Review: Are Climate Change and Air Pollution Making Neurologic Diseases Worse?

MINNEAPOLIS 鈥 People with neurologic diseases like headache, dementia, multiple sclerosis (MS) and Parkinson鈥檚 disease may experience worsening symptoms due to climate change, according to a scoping review of research published in the November 16, 2022, online issue of , the medical journal of the 好色先生. The review also found that stroke may become more prevalent due to climate change. 鈥淎lthough the international community seeks to reduce global temperature rise to under 2.7 潞F before 2100, irreversible environmental changes have already occurred, and as the planet warms these changes will continue to occur,鈥 said review author Andrew Dhawan, MD, DPhil, of Cleveland Clinic in Ohio and a member of the 好色先生. 鈥淎s we witness the effects of a warming planet on human health, it is imperative that neurologists anticipate how neurologic disease may change.鈥 For the review, researchers looked at studies published on climate change, pollutants, temperature extremes and neurologic disease between 1990 and 2022. They identified 364 relevant studies in three categories, including 289 studies on the impact of pollution, 38 studies on extreme weather events and temperature fluctuations and 37 studies on emerging neuroinfectious diseases. They included only studies on adults, not children. The studies highlighted the relationships between temperature variability and worsening neurologic symptoms, warming climates and tick- and mosquito-borne infections, as well as airborne pollutants and cerebrovascular disease rate and severity. The review showed extreme weather events and temperature fluctuations were associated with stroke incidence and severity, migraine headaches, hospitalization in dementia patients, and worsening of MS. It showed for emerging neuroinfectious diseases like West Nile virus, meningococcal meningitis and tick-borne encephalitis, climate change expanded the favorable conditions beyond the traditional geographic areas, and these diseases carried by animals and insects pose the risk of disease in new populations. The review also showed exposure to airborne pollutants, especially nitrates and fine particulate matter, also known as PM 2.5, pollutant particles of less than 2.5 microns in diameter, was associated with stroke incidence and severity, headaches, dementia risk, Parkinson鈥檚 disease, and worsening of MS. 鈥淐limate change poses many challenges for humanity, some of which are not well-studied,鈥 said Dhawan. 鈥淔or example, our review did not find any articles related to effects on neurologic health from food and water insecurity, yet these are clearly linked to neurologic health and climate change. More studies are needed on ways to reduce neuroinfectious disease transmission, how air pollution affects the nervous system, and how to improve delivery of neurologic care in the face of climate-related disruptions.鈥 A limitation is that the studies were conducted in resource-rich regions of the world, suggesting that the results may not apply in regions with fewer resources where such changes may be even more likely to occur. Learn more about brain health at , home of the 好色先生鈥檚 free patient and caregiver magazine focused on the intersection of neurologic disease and brain health. Follow Brain & Life on , and . When posting to social media channels about this research, we encourage you to use the hashtags #Neurology and #AANscience.

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The 好色先生 is the leading voice in brain health. As the world鈥檚 largest association of neurologists and neuroscience professionals with more than 40,000 members, the AAN provides access to the latest news, science and research affecting neurology for patients, caregivers, physicians and professionals alike. The AAN鈥檚 mission is to enhance member career fulfillment and promote brain health for all. A neurologist is a doctor who specializes in the diagnosis, care and treatment of brain, spinal cord and nervous system diseases such as Alzheimer's disease, stroke, concussion, epilepsy, Parkinson's disease, multiple sclerosis, headache and migraine.

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*While content of the 好色先生 (AAN) press releases is developed by the AAN along with research authors and Neurology® editors, we are unable to provide medical advice to individuals. Please contact your health care provider for questions specific to your individual health history or care. For more resources, visit the AAN's patient and caregiver magazine website, .