EMBARGOED FOR RELEASE UNTIL 4 PM ET, February 20, 2009

Young Smokers Increase Risk for Multiple Sclerosis

SEATTLE -

People who start smoking before age 17 may increase their risk for developing multiple sclerosis (MS), according to a study released today that will be presented at the ��ɫ����’s 61st Annual Meeting in Seattle, April 25 to May 2, 2009. The study involved 87 people with MS who were among more than 30,000 people in a larger study. The people with MS were divided into three groups: non-smokers, early smokers (smokers who began before age 17), and late smokers (those who started smoking at 17 or older), and matched by age, gender, and race to 435 people without MS. Early smokers were 2.7 times more likely to develop MS than nonsmokers. Late smokers did not have an increased risk for the disease. More than 32 percent of the MS patients were early smokers, compared to 19 percent of the people without MS. “Studies show that environmental factors play a prominent role in multiple sclerosis,” said study author Joseph Finkelstein, MD, PhD, of Johns Hopkins University School of Medicine, in Baltimore, MD, which conducted the study in collaboration with Veterans Affairs MS Center for Excellence. “Early smoking is an environmental factor that can be avoided.”

The ��ɫ����, an association of more than 21,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as multiple sclerosis, restless legs syndrome, Alzheimer’s disease, narcolepsy, and stroke. For more information about the ��ɫ����, visit www.aan.com . The AAN 61st Annual Meeting, the world’s largest gathering of neurology professionals, takes place April 25 to May 2, 2009, in Seattle. Visit www.aan.com/am for more information.

Editor's Notes: Study authors are available for interviews. Please contact Jenine Anderson, janderson@aan.com or Jay Mac Bride, jmacbride@aan.com. To access 2009 AAN Annual Meeting abstracts available February 25, 2009, visit http://www.aan.com/go/science/abstracts. Late-breaking abstracts will be featured in press release at the 2009 AAN Annual Meeting in Seattle.