Abstract Details

Title Efficacy of an Outpatient Cognitive Rehabilitation Program in Patients with Acquired Brain Damage in Connection with the Time Elapsed before Treatment Initiation

Topic Neural Repair/Rehabilitation

Presentation(s) P04 - (-)

Poster/Presentation
Number 037

Objective

Background BACKGROUND: Studies conducted in patients with ABD indicate that the response to CR therapy may be increased when the treatment is administered during the months immediately after the damage. However, the different functions can show different recovery rates, and some of them can improve even years after the damage.

Design/Methods DESIGN/METHODS: The results from 75 patients (49 male/26 female, age: (mean ± SD) 50.2±20.1 years; education 14.3±3.2 years; Mini-Mental State Examination initial score 26.2±3.2) with cognitive disturbances secondary to ABD (51 cases with history of stroke, 17 cases of traumatic brain injury, 7 cases of other ABD etiologies) were analyzed. The subjects enrolled completed cognitive-behavioral, functional, and social scales at baseline and at the end of the CR therapy. Tools: Subjective Memory Questionnaire, Depression Inventory, Anxiety/Depression Rating Scale, instrumental and basic Activities of daily living, Quality of Life and neuropsychiatric symptoms. For each tool, the difference between the rates before and after the therapy was calculated.

Results RESULTS: There were correlations between the time elapsed and the perceived improvement in memory, quality of life and mood (p<.05). An ANOVA showed differences between the patients who started the therapy within one year after the damage and those who started after a longer period, in the areas of subjective memory and quality of life (p<.05). The comparison of the groups represented by the extreme quartiles [< 6 months (n=23), > 44 months (n=18)] showed a similar pattern of results, but with increased discrimination between variables.

Conclusions CONCLUSIONS: Results suggest that the delay in CR initiation has a negative impact on treatment efficacy in ABD patients. Such differences can be found in the cognitive, behavioral and social functioning measurements.

Authors/Disclosures
Galeno Rojas, MD (British Hospital. INEBA, Al Lado Del Supermercado Chino.) PRESENTER	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
Fernando J. Caceres, MD	No disclosure on file
	No disclosure on file

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