Abstract Details

Title Analog Restless Legs Syndrome Rating Scale (ARLS) - A Novel Bedside and Clinic Tool

Topic Sleep

Presentation(s) P05 - (-)

Poster/Presentation
Number 026

Objective

Background BACKGROUND: Restless legs syndrome (RLS) is a common movement disorder characterized by an inescapable urge to move the limbs during evening hours. Visual analog scales are used to determine severity of discomfort in RLS, however analog measures have not been compared to overall severity based upon the more widely used IRLS.

Design/Methods DESIGN/METHODS: Monthly questionnaires (ARLS and IRLS) were administered to untreated subjects with RLS, enrolled as part of an IRB approved prospective study. The ARLS comprised of the general severity of symptoms, the urge to move and alleviation of symptoms by movement, each scored from 0 to 100. The relationship between the normalized total IRLS score and the normalized total and sub-scores of the ARLS was assessed.

Results RESULTS: Twenty-six subjects with idiopathic, untreated RLS were studied. Mean age was 49.1+/-5.6 years and 84.7% were Caucasian. The average total IRLS score was 14.1±5.8, while the mean value of ARLS, averaged over its three components, was 43±22.5. The relationship between normalized overall severity component of the ARLS and normalized IRLS was optimally described with a linear function, the correlation coefficient was 0.6 and slope 1.2. The relationship between the urge to move and IRLS score was best described by a sigmoid function. A negative correlation between RLS severity measured with IRLS and improvement following movement was observed and residual symptoms after movement positively correlated with the normalized IRLS score.

Conclusions CONCLUSIONS: We conclude that the ARLS has comparable efficacy to IRLS in estimating overall disease severity. In addition it is rapidly administered and easily interpreted by the subjects. Further studies are necessary to determine its use in temporal assessment of patients on treatment for RLS.

Authors/Disclosures
Aasef Shaikh, MD PRESENTER	Dr. Shaikh has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Acorda.
Prachi Mehndiratta, MD	Dr. Mehndiratta has nothing to disclose.
Carmela Gonzales, MD (Mercy Health)	No disclosure on file
	No disclosure on file
Brian Koo, MD	Dr. Koo has received personal compensation in the range of $500-$4,999 for serving as a Consultant for American Regent. Dr. Koo has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Speckhals Law. The institution of Dr. Koo has received research support from Department of Defense.

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