Abstract Details

Title A Tale of Two Restless Sisters

Topic Movement Disorders

Presentation(s) P02 - (-)

Poster/Presentation
Number 067

Objective

Background BACKGROUND: Restless Leg Syndrome (RLS) or Willis-Ekbom disease is a neurological condition characterized by an irresistible urge to move the legs. Most recently, the uncomfortable urge or sensations were also linked to affect other body parts such as arms, torso, and tongue. Moving the affected body part modulates the sensations, providing temporary relief.

Design/Methods DESIGN/METHODS: Case report.

Results RESULTS: Two sisters with severe restless legs (RLS) and arms (RAS)syndrome were identified during routine follow up. AC is a 75 yo woman with RLS/RAS, PMH of DM, PN, Anxiety, depression and renal disease, presented to clinic with very severe symptoms (RLS score 35/40 pre medication). Ropinirole and Pramipexole were added. On her next routine follow up, RLS score was 19/40 (note: gabapentin was tried but was stopped due to ADR). She also opted to add Rasagiline to her regimen. Three months later, she returned for follow up reporting improvement in her symptoms (15/40, PGIC 3). JC is a 71 yo woman with TLS/RAS, DM, PN, Anxiety and depression presented to clinic with very severe symptoms (RLS score 38/40 pre medication). Pramipexole and gabapentin were prescribed. At follow up, RLS score was 37/40. Because of neuropathy, TENS unit was applied (RLS score 35/40). At next follow up she opted to add Rasagiline to her regimen. Three months later, she returned for follow up reporting improvement on her symptoms (21/40, PGIC 4).

Conclusions CONCLUSIONS: Rasagiline was well tolerated during the follow-up. We suggest that Rasagiline could represent a useful adjunct therapeutic option in the treatment of RLS.

Authors/Disclosures
Maria V. Alvarez, MD (Neurology Assciates) PRESENTER	No disclosure on file
Patrick M. Grogan, MD, FAAN (Neurology Associates)	No disclosure on file
	No disclosure on file

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