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Abstract Details

Risk Factors in Young Adults with Intracererbal Hemorrhage without Angiographically Identifiable Structural Causes
Cerebrovascular Disease and Interventional Neurology
P04 - (-)
055
BACKGROUND: In previous population studies, hypertension (HTN) was shown to be a dominant risk factor in patients 18-49. Some reports have since suggested improved overall management of HTN in the US. This may suggest a change in the risk profile of younger patients with AN ICH. We aimed to corroborate this change and also re-examine other risk factors and demographics in this population.
DESIGN/METHODS: Medical records of patients admitted to our hospital with ages between18-49 were identified using ICD-9 codes. Those with AN ICH, evident by normal digital subtraction or radiologic angiography, were isolated and analyzed.
RESULTS: Of 502 records, 85 met our analysis criteria. There were 41% females and 59% men with a mean age 40. Forty eight were Caucasians, 25 Blacks, 3 Hispanics, 1 Middle-Eastern, and 8 undetermined. HTN was identified in 42%. Thirty five percent were smokers, 24% used alcohol regularly, and 6% abused cocaine. Twenty percent met the diagnostic criteria for diabetes mellitus. Anticoagulation-related ICH was documented in 5% and 13% were on daily antiplatelet agents. Underlying infections, either acute or chronic, were present in 19%. Locations of hemorrhages were lobar in 47%, deep in 33%, and the rest were infratentorial.
CONCLUSIONS: HTN remains the primary risk factor in young adults with AN ICH. The results of this study suggest that more persuasive efforts should be undertaken to raise awareness of the harmful effects of HTN in this population. Early identification of HTN and cessation of smoking could help decrease the risk of ICH in this population.
Authors/Disclosures
Alex Perchuk, MD (OhioHealth Marion General Hospital)
PRESENTER
No disclosure on file
No disclosure on file
No disclosure on file
Reza Behrouz, DO, PhD, FAAN (University of Texas Health Science Center San Antonio) No disclosure on file
No disclosure on file