Abstract Details

Title Seizures and Epilepsy after Stroke: Resources and Costs Assessment

Topic Epilepsy

Presentation(s) P03 - (-)

Poster/Presentation
Number 118

Objective

Background BACKGROUND: Stroke is the major cause of disability and is associated with outstanding costs. Seizures following stroke occur in about 10% of patients overall, especially in the first few weeks However, resource consumption and costs are underestimated; they are not usually recognized as seizure-related costs.

Design/Methods DESIGN/METHODS: The study was hospital-based, case-control. Cases and controls were identified from the prospective consecutive cohort of patients admitted with acute stroke and followed up to 18 mo after the stroke onset (N=298). During the hospital stay (approx. 30 days) 30 patients with seizures were identified. There were 24 patients with early seizures only, 3 patients with early and late seizures and 3 patients with late seizures only. We searched two or three controls for each case. Seventy stroke controls (without seizures) were carefully selected. Controls were matched to cases according to the stroke severity on admission, focus location, co-morbidity, age, gender. Consumption of hospital resources and direct healthcare costs (inpatient care, drug costs, medical devices and diagnostic procedures) was evaluated (per patient) in cases and controls.

Results RESULTS: NIHSS (M±SD) were similar in both cohorts at admission (cases/controls 10.5±3.7 vs. 9.5±3.1) and at discharge (3.3±1.8 vs. 3.8±2.9). However, mortality rate was significantly higher in stroke patients with seizures (50.0% vs. 5.7%). Consumption of resources was significantly higher in patients with seizures in the following domains: days in the ICU, number of CT/MRI, consultations, X-ray, endoscopic manipulations. That translated to higher direct costs in patients with stroke and seizures vs. stroke patients.

Conclusions CONCLUSIONS: Seizures after stroke substantially increase direct costs and resource consumption. They contribute to poor prognosis of stroke and increases mortality.

Authors/Disclosures
Alla Borisovna Guekht, PhD (Centre of Psychoneurology Named By Solovyeva) PRESENTER	The institution of Prof. Guekht has received research support from Russian Science Foundation .
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file

��ɫ��

��ɫ��