Abstract Details

Title Incidence and Types of Seizures in Acute - A Single Center Experience

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P01 - (-)

Poster/Presentation
Number 252

Objective

Background BACKGROUND: Stroke is identified as the most common cause of epilepsy in the elderly and may account for over 50% of seizures. Seizures can occur early or later in the course of disease.

Design/Methods DESIGN/METHODS: 1211 patients with acute stroke that presented to a University hospital in New Delhi, India between January 2001 and June 2012 were prospectively analyzed for the occurrence of seizures. Post-stroke seizures (PSS) were classified as new onset seizure at the onset or following an acute stroke. Seizure types were classified as generalized or focal. The onset of seizures was classified as immediate, early or late if occurring within 24 hours, day 1 to 2 weeks, or after 2 weeks respectively.

Results RESULTS: We identified 95 patients (68 males) that developed post-stroke seizures. There was no statistically significant difference in the risk factors such as Hypertension, smoking, diabetes and coronary artery disease between those with and without seizures. In the PSS group, seizures occurred more frequently in those with ischemic stroke as compared to hemorrhagic stroke (p = 0.017, RR 3.058, 95% CI 1.1343 - 8.2449). Seizures were also more common in MCA territory infarcts as compared to ACA or PCA territory infarcts with a trend towards statistical significance (p =0.06). Focal seizures occurred in 43 (70.6 %) patients with aphasia. Twenty-one (48.8 %) of these had early seizures and 22 (51.2 % %) had late onset seizures.

Conclusions CONCLUSIONS: This is one of the largest studies describing occurrence of seizures post stroke. Seizures occurred in 7.9 % of patients with stroke. Focal seizures were the most common type and MCA territory infarcts were more likely to be associated with seizures. PSS were more likely to occur in those with ischemic infarcts as compared to hemorrhagic infarcts.

Authors/Disclosures
Man Mohan Mehndiratta, MD, MBBS, FAAN (B.L.Kapur Hospital (Max Health Care Group), Centre for Neurosciences) PRESENTER	Dr. Mehndiratta has nothing to disclose.
Prachi Mehndiratta, MD	Dr. Mehndiratta has nothing to disclose.
Munish Kumar, MD	No disclosure on file
Joseph Benes, MD	Dr. Benes has nothing to disclose.
Rolando J. Giannaula, MD	No disclosure on file

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