Abstract Details

Title Radicular Claudication

Topic Clinical Neurophysiology

Presentation(s) P02 - (-)

Poster/Presentation
Number 227

Objective

Background BACKGROUND: Low back pain is a frequent affection with serious impact on quality of life and capability to work. We present a series of 16 patients suffering from low back pain selected from a larger group of subjects referred with a preliminary diagnosis of lumbosacral radiculopathy.

Design/Methods DESIGN/METHODS: Sixteen patients aged 32-68 years were selected from 371 consecutive patients referred to our EMG laboratory with a clinical suspicion of radiculopathy. All the selected subjects complained of bilateral lumbosacral pain irradiating to buttocks and/or thighs and calves while walking or standing, disappearing while lying down or sitting position. None of them had a metabolic or vascular disease. Lumbosacral MRI did not disclose any radicular compression. Fifteen healthy persons aged 35-65 years served as controls. ENG/EMG was carried out in all patients by the same blinded to MRI results examiner - M , F and H-waves in the peroneal and tibial nerves were analyzed. We compared BMI in the two groups. The results were compared using student T-test (p<0,05).

Results RESULTS: We found significantly decreased mean F-wave velocity, increased F-wave chronodispersion and decreased velocity of the H-reflex in 14 patients (87%) in the diseased group. BMI was significantly increased in the group of patients with pain in comparison to healthy persons.

Conclusions CONCLUSIONS: The parameters of F-wave and H-reflex seem to be useful in early detection of radicular compression before constituted radiculopathy appears. Mechanical gravitational compression of the lowest lumbar roots in upright position in obese patients seems to be the major cause of the disorder. We propose the term of radicular claudication instead of neural claudicaiotn as most appropriate to this clinical situation, we also formulate diagnostic criteria for this condition.

Authors/Disclosures
PRESENTER	No disclosure on file
Wojciech Kozubski, MD, PhD (University of Medical Sciences in Poznan)	No disclosure on file
Bruce D. Trapp, PhD (Cleveland Clinic)	Dr. Trapp has received personal compensation for serving as an employee of Renovo Neural Inc.. The institution of Dr. Trapp has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Therini Bio, Inc.. Dr. Trapp has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi Genzyme. Dr. Trapp has received personal compensation in the range of $50,000-$99,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Disarm Therapeutics. Dr. Trapp has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Kantonsspital Aarau AG. Dr. Trapp has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for triMS.online. The institution of Dr. Trapp has received research support from Genzyme Corporation. The institution of Dr. Trapp has received research support from ALS Association. The institution of Dr. Trapp has received research support from National Institute of Neurological Disorders and Stroke.
	No disclosure on file

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