Abstract Details

Title Patterns of Collateral Formation in Basilar Artery Steno-Occlusive Diseases

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P05 - (-)

Poster/Presentation
Number 214

Objective

Background BACKGROUND: Augmentation of collateral flow is proposed as a method to reduce ischemic injury in the posterior circulation. However, collateral formation in basilar artery stenosis and basilar artery occlusion has not been studied thoroughly.

Design/Methods DESIGN/METHODS: We identified 24 consecutive patients admitted over a 4 year period with angiographically demonstrated basilar artery stenosis more than 50% or occlusion. Angiographic images were reviewed for pattern of collaterals by a blinded reviewer. A new grading system by Qureshi1 et. al was utilized for grading. Grades I and II had retrograde filling of the basilar artery through PCA with or without filling of the superior cerebellar artery, respectively. Grades III and IV were bilateral or unilateral anastomoses of cerebellar arteries or PCAs, respectively. Risk factors such as age, gender, race/ethnicities, co-morbidities, NIHSS sore on admission and discharge, tPA administration, in-hospital complications, and discharge status measured by the modified Rankin score were ascertained.

Results RESULTS: The collaterals were categorized as: Grade I A (n=8), Grade IIIA (n=5), and none (n=11). No patient had Grade II collaterals. Grade IA collaterals were more frequent in patients with basilar artery occlusion than those with basilar artery stenosis. The rate of good outcomes (mRS 0-2) at discharge was significantly higher among patients with IA collaterals compared with patients with grade IIIA collaterals (62% vs. 20%). The rate of good outcomes was 54% of patients without collaterals.

Conclusions CONCLUSIONS: The pattern of collateral formation in basilar artery stenosis and basilar artery occlusion varies and is associated with patient outcomes.

Authors/Disclosures
Syeda L. Alqadri, MD (KabaFusion Holders LLC) PRESENTER	No disclosure on file
	No disclosure on file
Masaki Watanabe (University of Minnesota)	No disclosure on file
Hamza I. Maqsood, MD (Dept of Neurology)	Dr. Qureshi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for AstraZeneca.
Daniel Weintraub	Daniel Weintraub has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Clintrex. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Janssen. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sage. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Scion. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Signant. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sunovion. Daniel Weintraub has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Modality.ai. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Cerevel. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for CuraSen. Daniel Weintraub has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Takeda. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Boehringer Ingelheim. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Daniel Weintraub has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Acadia. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Movement Disorder Society. The institution of Daniel Weintraub has received research support from NIH. The institution of Daniel Weintraub has received research support from Fox Foundation. The institution of Daniel Weintraub has received research support from IPMDS. Daniel Weintraub has received intellectual property interests from a discovery or technology relating to health care.

��ɫ��

��ɫ��