Abstract Details

Title Financial Errors in Dementia: Testing a Neuroeconomic Conceptual Framework

Topic Aging and Dementia

Presentation(s) P07 - (-)

Poster/Presentation
Number 132

Objective

Background BACKGROUND: Financial errors by patients with dementia can have devastating personal and family consequences. Existing measures of financial management in dementia focus on whether patients possess financial capacity (a related concept), as opposed to specific errors that patients make. Different dementia syndromes target specific neural systems that may be reflected in susceptibility to different types of error. If risks for different errors in different syndromes can be established, this may aid in early recognition and diagnosis of dementia, and clinicians will be better-equipped to counsel patients and families to avoid situations that place them at greatest risk.

Design/Methods DESIGN/METHODS: Systematic, retrospective, blinded chart review of demographically-balanced cohorts of patients with Alzheimer's disease (AD, n=100) and behavioral variant frontotemporal dementia (bvFTD, n=50). Reviewers recorded specific reports of financial errors according to a conceptual framework identifying patient cognitive and affective characteristics, and contextual influences, conferring susceptibility to each error.

Results RESULTS: Specific financial errors were reported for 49% of AD and 70% of bvFTD patients (p = 0.012). AD patients were more likely than bvFTD patients to make amnestic errors (p < 0.001), while bvFTD patients were more likely to spend excessively (p = 0.004) and to exhibit other behaviors consistent with diminished sensitivity to losses and other negative outcomes (p < 0.001). Exploratory factor analysis identified a social/affective vulnerability factor associated with errors in bvFTD, and a cognitive vulnerability factor associated with errors in AD.

Conclusions CONCLUSIONS: Financial errors are common and important symptoms of AD and bvFTD. Different factors influence vulnerability to financial errors in different syndromes, with implications for early diagnosis and subsequent risk prevention.

Authors/Disclosures
Winston Chiong, MD (UCSF Memory and Aging Center) PRESENTER	The institution of Dr. Chiong has received research support from the National Institutes of Health. The institution of Dr. Chiong has received research support from the Dana Foundation. Dr. Chiong has received personal compensation in the range of $500-$4,999 for serving as a member, NeuroEthics Working Group with National Institutes of Health.
Dorothy Ko (Genervon Biopharmaceuticals LLC)	No disclosure on file
	No disclosure on file
	No disclosure on file
Simona Malucchi	No disclosure on file
Bruce L. Miller, MD, FAAN (University of California, San Francisco)	Dr. Miller has nothing to disclose.
Howard J. Rosen, MD (UCSF)	Dr. Rosen has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly . Dr. Rosen has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Alector. The institution of Dr. Rosen has received research support from NIH. The institution of Dr. Rosen has received research support from State of CA. Dr. Rosen has a non-compensated relationship as a Consultant with Prevail Therapeutics that is relevant to AAN interests or activities. Dr. Rosen has a non-compensated relationship as a consultant with Alchemab that is relevant to AAN interests or activities.

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