Abstract Details

Title A Blood Glucose Monitoring Strip Could Be Used for an Early Glycorrhachia Determination

Topic Global Health

Presentation(s) P04 - (-)

Poster/Presentation
Number 238

Objective

Background BACKGROUND: CSF analysis is a commonly performed laboratory test which includes proteins and glucose levels, cell counts, microscopic examination, culture, etcetera. Many different situations can cause hypoglycorrhachia, and therefore CSF glucose level itself could be useful in supporting a presumptive clinical diagnosis (e.g. Infections). A blood glucose meter is an electronic device that uses an amperametric technology employing a glucose oxidase reaction for measuring the blood glucose level.

Design/Methods DESIGN/METHODS: In patients who underwent a diagnostic lumbar puncture (LP), we used BGMS to measure CSF glucose level early after LP was performed. Results were compared with our standard laboratory determinations. All patients gave their written consent.

Results RESULTS: 45 patients were included. Mean age was 40.8 years old (range 15-84). Reasons for LP: meningitis: 4 (8.9%), headache 8 (17.8%), demyelinating disease suspicion 21 (46.6%), myelopathy 4 (8.9%), other causes: 8 (17.8%). Traumatic LP: 7 (17.5%). Mean intracranial opening pressure: 19 cm-H2O (range 5-50). The percent accuracy in CSF glucose determination using BGMS, when compared to our standard laboratory determination, was 88%.

Conclusions CONCLUSIONS: These results demonstrate a substantial equivalence in CSF glucose levels between BGMS and standard laboratory determinations. We believe that an early glychorraquia determination through BGMS could be helpful for clinicians when making quick decisions in different clinical scenarios. Further studies are necessary to support our findings.

Authors/Disclosures
PRESENTER	No disclosure on file
	No disclosure on file
Jeffrey R. Buchhalter, MD, FAAN (Buchhalter Consulting PLLC)	Dr. Buchhalter has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Epilepsy Foundation. Dr. Buchhalter has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Epilepsy Study Consortium. Dr. Buchhalter has received personal compensation in the range of $500-$4,999 for serving as a Consultant for UCB. Dr. Buchhalter has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biocodex. Dr. Buchhalter has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for UCB. Dr. Buchhalter has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biocodex. Dr. Buchhalter has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Neurona.
Pedro Rodriguez Cruz	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
David Ezpeleta	No disclosure on file

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