Abstract Details

Title Significant Improvements on Muscle Performance and Walking Capacity after Progressive Resistance Training (PoRT) and Core and Stability Training (CoaST) for People with MS

Topic Clinical Neurophysiology

Presentation(s) P01 - (-)

Poster/Presentation
Number 036

Objective

Background Multiple sclerosis (MS) is a chronic inflammatory disease which may result in motor weakness, spasticity, poor balance that may lead to severe progressive limitations of functioning in daily life. The decrease of walking capacity is a common burden of patients in MS. Resistance training is a method to strengthen individually muscle groups but little is known about the influence on muscle performance and walking abilities.

Design/Methods A randomized controlled three-armed multi-center trial with a 6 months study period was performed. SUBJECTS: 61 patients with MS and an EDSS from 1-6 were randomly allocated to one of the three groups. INTERVENTION: Group 1 received a progressive resistance training (PoRT) using weight machines. Group 2 performed a core and stability training (CoaST) in group settings performed under guidance of one therapist. Both intervention groups followed a detailed exercise protocol. The training sessions were performed for 60 minutes once week. Group 3 (Control) followed normal daily living with no further increase of physical activities. MAIN OUTCOME PARAMETERS: The main measurement was a 1 repetition maximum test of 5 different muscle groups. Secondary objectives were walking capacity, balance and spasticity. Patients were assessed at baseline and 12 weeks post treatment with a standardized examination. A further assessment followed after further 24 weeks.

Results Significant improvements on muscle performance could be found in both intervention groups. The control group showed no differences after 12 weeks of waiting.

Conclusions Progressive resistance training (PoRT) and core and stability training (CoaST) in groups could improve muscle performance and walking distance for people in MS. Both physical interventions indicate to improve independence in daily life.

Authors/Disclosures
PRESENTER	No disclosure on file
	No disclosure on file
Glen H. Stevens, DO, PhD, FAAN (Cleveland Clinic Foundation)	The institution of Dr. Stevens has received personal compensation in the range of $50,000-$99,999 for serving on a Scientific Advisory or Data Safety Monitoring board for NIH. Dr. Stevens has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for EBSCO. The institution of Dr. Stevens has received research support from National Cancer Institute.
	No disclosure on file
Martin Marziniak, PhD (Klinik fur Neurologie)	No disclosure on file
	No disclosure on file

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