Abstract Details

Title Sweetened-Beverages, Coffee, and Tea in Relation to Depression among Older US Adults

Topic Behavioral Neurology

Presentation(s) P05 - (-)

Poster/Presentation
Number 122

Objective

Background BACKGROUND: Sweetened-beverages, coffee and tea are commonly consumed worldwide and have important physical and mental health consequences.

Design/Methods DESIGN/METHODS: We prospectively evaluated consumptions of these beverages, in relation to depression among 263,925 older US adults. Beverage consumptions were assessed in 1995-1996, and 11,311 depression diagnoses since 2000 were self-reported in 2004-2006. Odds ratios (OR) and 95% confidence intervals (CI) were derived from multivariate logistic regressions.

Results RESULTS: Drinking sweetened-beverages was associated with higher depression risk, whereas coffee drinking was weakly related to lower risk. The OR and 95%CI comparing ?4 cans/cups per day with none were 1.30 (1.17-1.44) for soft drinks, 1.38 (1.15-1.65) for fruit punches, and 0.91 (0.84-0.98) for coffee (all P for trend < 0.0001). Further analysis seemed to suggest stronger associations with diet drinks than with regular. The ORs between extreme categories were 1.31 (1.16-1.47) for diet versus 1.22 (1.03-1.45) for regular soft drinks, 1.51 (1.18-1.92) for diet versus 1.08 (0.79-1.46) for regular fruit punches, and 1.25 (1.10-1.41) for diet versus 0.94 (0.83-1.08) for regular iced tea. Consistently, constituent-based analyses showed higher depression risk with aspartame intake [ORs between extreme quintiles: 1.36 (1.29-1.44)], and lower risk with caffeine intake [corresponding OR 0.83 (0.78-0.89)].

Conclusions CONCLUSIONS: This large prospective study suggests that frequent consumption of diet sweetened-beverages may increase depression risk among older adults, whereas coffee consumption may lower the risk.

Authors/Disclosures
Honglei Chen, MD, PhD, FAAN (Michigan State University) PRESENTER	The institution of Dr. Chen has received research support from NIH, . The institution of Dr. Chen has received research support from DoD. The institution of Dr. Chen has received research support from Parkinson's Foundation. The institution of Dr. Chen has received research support from MSU GE and Gibby vs. Parky project.
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
Rohit Bakshi, MD, FAAN	Dr. Bakshi has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for EMD Serono. Dr. Bakshi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Sanofi. The institution of Dr. Bakshi has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Journal of Neuroimaging. The institution of Dr. Bakshi has received research support from Bristol Myers Squibb. The institution of Dr. Bakshi has received research support from EMD Serono. The institution of Dr. Bakshi has received research support from Novartis.
	No disclosure on file
	No disclosure on file

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