Abstract Details

Title A Critical Analysis of the Components of the Time Interval between Symptom Onset and Recanalization in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P02 - (-)

Poster/Presentation
Number 049

Objective

Background BACKGROUND: The time interval between symptom onset to recanalization is the most important determinant of favorable outcomes following endovascular treatment of acute ischemic stroke, but is subject to great variability between institutions and patients. There are various components of the time interval between symptom onset and recanalization that require component specific strategies to reduce treatment delays.

Design/Methods DESIGN/METHODS: We analyzed data derived from consecutive acute ischemic stroke patients treated with endovascular therapy over a 7-year period. Demographics characteristics, National Institutes of Health Stroke Scale (NIHSS) score before and after the procedure, and discharge modified Rankin scale (mRS) were collected. The Qureshi grading scale was used to categorize angiographic recanalization. Time interval between symptom onset and recanalization/termination of procedures was divided into 4 intervals between symptom onset, ED arrival, CT scan, microcatheter placement, and recanalization/completion of procedure. We first found the time interval with the longest median and most variance, and then adjusted for intubation status, IV thrombolysis, and time of ED arrival (8am-5pm vs 5pm-8am).

Results RESULTS: We analyzed data from 336 consecutive acute ischemic stroke patients who underwent endovascular treatment, with mean age±SD: 65 ±16.3 years; 174 (52%) men, and mean NIHSS score ± SD: 15.4± 7.1. Arrival to CT scan had the shortest median time of 18 minutes (see Figure 1). The time interval component with the maximum delay and variance was CT scan to initialization of angiogram (mean 134 minutes, median 114±96.9 mins). Time intervals are provided in the figure below.

Conclusions CONCLUSIONS: There is a need for hospital administration to help with strategies to reduce the time from CT scan to initialization of angiogram in order to reduce the treatment delay observed in patients undergoing endovascular treatment for acute ischemic stroke.

Authors/Disclosures
Basit Rahim, MD (Virginia Commonwealth University Health System) PRESENTER	No disclosure on file
Ameer Hassan, DO (Valley Baptist Medical Center)	Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Medtronic. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Stryker. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Penumbra. Dr. Hassan has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Cerenovus. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Viz.ai. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Genentech. Dr. Hassan has received research support from GE Healthcare.
	No disclosure on file
Saqib A. Chaudhry, MD	Dr. Chaudhry has nothing to disclose.
Gustavo J. Rodriguez, MD (Gustavo J. Rodriguez)	Dr. Rodriguez has nothing to disclose.
Hamza I. Maqsood, MD (Dept of Neurology)	Dr. Qureshi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for AstraZeneca.
David Miller	No disclosure on file

��ɫ��

��ɫ��