Abstract Details

Title The Role of Gender in the Presence of Collateral Vessels in the Circle of Willis: A Prospective Study

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P02 - (-)

Poster/Presentation
Number 029

Objective

Background BACKGROUND: Patients undergoing carotid revascularization have been shown to have different outcomes based on gender with women at higher risk of stroke during carotid procedures than men. Studies into the role that vessel size contributes to stroke risk have shown no effect, suggesting in fact that smaller carotid arteries are lower risk of stroke. We investigated whether the collateral vessels in the Circle of Willis may play a role in stroke risk. Other studies have shown that patients with adequate collaterals have a lower risk of stroke from carotid disease, but no study has yet been done to determine if gender plays a role in the presence of such collaterals.

Design/Methods DESIGN/METHODS: We studied a prospective, consecutive series of patients undergoing cerebral angiography for any reason. Using a scoring system of 1-10, interventional radiologists quantified the presence and adequacy of collaterals in each subject. Collaterals included bilateral A1, bilateral P1, bilateral Pcomm and the Acomm segments. We studied 69 women and 46 men.

Results RESULTS: Our study showed that on average men scored 7.04 and women 7.33 for presence and adequacy of collaterals, such that women have more collaterals than men with Chi square probability level of 0.054.

Conclusions CONCLUSIONS: Based on our study, women are more likely to have an angiographically complete Circle of Willis. Whether the collateral circulation in women is potentially impaired from factors not assessed by angiography, such as decreased quantitative flow, is uncertain and the subject of a future study.

Authors/Disclosures
Sepideh Mokhtari, MD (Moffitt Cancer Center) PRESENTER	Dr. Mokhtari has nothing to disclose.
John J. Volpi, MD	Dr. Volpi has received personal compensation in the range of $500-$4,999 for serving as a Consultant for NovaSignal. Dr. Volpi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for W.L. Gore. Dr. Volpi has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Diamedica. Dr. Volpi has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Janssen. Dr. Volpi has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Amgen. Dr. Volpi has received intellectual property interests from a discovery or technology relating to health care.
Yi Zhang, MD (NYU Langone)	Dr. Zhang has nothing to disclose.
	No disclosure on file
	No disclosure on file
	No disclosure on file

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