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Abstract Details

Risk of Subarachnoid Hemorrhage among Patients Infected with Human Immunodeficiency Virus
Critical Care/Emergency Neurology/Trauma
P05 - (-)
199
BACKGROUND: SAH data among HIV/AIDS patients is limited to case reports.
DESIGN/METHODS: The Nationwide Inpatient Sample (NIS 2002-2010) identified all patients with primary diagnosis of SAH in United States between 2002-2009. We identified the patients with HIV/AIDS and those who were HIV negative and stratified them by gender and age: 13-24, 25-34, 35-44, 45-54 and 55+ years. We obtained the number of people living with AIDS in the United States population from the Centers for Disease Control and Prevention for 2002 according to the same age groups. Using the 2000 United States census information, we identified the number of people in the general population and subtracted the AIDS cases within the respective age groups. The relative risk of developing SAH in AIDS patients versus HIV negative patients was obtained between 2002-2009.
RESULTS: The age adjusted annual incidence of SAH was 62.3 per 100,000 and 20.2 per 100,000 among HIV/AIDS positive and HIV negative persons. The age adjusted annual relative risk for SAH among HIV/AIDS positive persons was 3 (95% confidence interval 2.4-3.8). HIV positive women had higher incidence of SAH compared to HIV positive males, except among the 13-24 year old group. The SAH rate ratio decreased with each increasing decade when compared with HIV negative patients: 13-24 (25), 25-34 (8.6), 35-44 (3), 45-54 (2.4) and 55+ years (1.6). The 7 year SAH incidence rate in HIV positive men between 13-24 years was 29 times more than in HIV negative men; the SAH incidence among HIV positive women was 18 times that of HIV negative women.
CONCLUSIONS: HIV/AIDS positive persons, particularly young individuals, have an increased risk of SAH.
Authors/Disclosures
Haralabos Zacharatos, MD
PRESENTER 		Dr. Zacharatos has nothing to disclose.
A. M. Barrett, MD, FAAN (UMass Memorial) The institution of Dr. Barrett has received research support from Veterans Health Association. The institution of Dr. Barrett has received research support from National Institutes of Health. The institution of Dr. Barrett has received research support from Mabel H Flory Trust. Dr. Barrett has received personal compensation in the range of $0-$499 for serving as a author, chapter with WebMD. Dr. Barrett has received personal compensation in the range of $10,000-$49,999 for serving as a scientific advisor with Winifred Masterson Burke Foundation.
Basit Rahim, MD (Virginia Commonwealth University Health System) No disclosure on file
No disclosure on file
Ameer Hassan, DO (Valley Baptist Medical Center) Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Medtronic. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Stryker. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Penumbra. Dr. Hassan has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Cerenovus. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Viz.ai. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Genentech. Dr. Hassan has received research support from GE Healthcare.
No disclosure on file
Hamza I. Maqsood, MD (Dept of Neurology) Dr. Qureshi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for AstraZeneca.