Abstract Details

Title Associations of Race with Self and Informant Complaints of Cognitive Difficulties in a Community Based Sample of Non-Demented Elders

Topic Aging and Dementia

Presentation(s) P07 - (-)

Poster/Presentation
Number 148

Objective

Background BACKGROUND: Though self- and informant reports of cognitive difficulties are essential to the diagnosis of dementia, they have not been investigated in diverse groups.

Design/Methods DESIGN/METHODS: The Einstein Aging Study (EAS) is a community-based longitudinal study of Bronx adults 70+. Self- and informant reports of cognitive status were assessed using select items from the CERAD clinical history questionnaire, Albert Einstein Health Self-Assessment Form, and Geriatric Depression Scale, short form (GDS). We used baseline data from the Einstein Aging Study to assess the rates and associations of self and informant complaints (each was stratified into low, medium, or high rates) in blacks and whites. Using logistic regression models, we adjusted for age, gender, education (>12 years vs. LE to 12 years), memory status, measured by the Free and Cued Selective Reminding Test (dichotomized as free recall scores <27 versus >=27). In a second model we also adjusted for depression (dichotomized as GDS scores <7 versus >= 7).

Results RESULTS: The sample included 1729 individuals (27% black; 61% female). Using the lowest level of self-reported complaints as the reference group, blacks were more likely than whites to be in the medium (OR=1.30, CI: 1.01-1.67, P=0.04) and high complaint groups (OR=1.37, CI: 1.02-1.846, P=0.04). Results were not materially altered by adjustment for depression. An opposite, though non-significant pattern was found for informant complaints (n=908), where black race was associated with lower levels of informant complaints (OR=0.82, CI: 0.61-1.10, P=0.1911).

Conclusions CONCLUSIONS: Non-demented black older adults showed significantly higher level of self-reported memory complaints than whites even after adjusting for age, gender, education, and memory. Informant complaints show no significance difference between racial groups. The predictive validity of these complaints will be assessed in our longitudinal study.

Authors/Disclosures
Alejandra Garland Becerra, MD PRESENTER	Dr. Garland Becerra has nothing to disclose.
Dale J. Lange, MD, FAAN (Lange Neurology, PC)	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
Richard B. Lipton, MD, FAAN (Albert Einstein College of Medicine)	Dr. Lipton has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Allergan/Abbvie. Dr. Lipton has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Amgen. Dr. Lipton has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Biohaven. Dr. Lipton has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Eli Lilly. Dr. Lipton has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Lundbeck. Dr. Lipton has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for GlaxoSmithKline. Dr. Lipton has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Teva. Dr. Lipton has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Vedanta. Dr. Lipton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Merck. Dr. Lipton has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Grifols. Dr. Lipton has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Pfizer. Dr. Lipton has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Axon. Dr. Lipton has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Satsuma. Dr. Lipton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genentech. Dr. Lipton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Cool Tech. Dr. Lipton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for BDSI. Dr. Lipton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Linpharma. Dr. Lipton has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Axsome. Dr. Lipton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Clexio. Dr. Lipton has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Shiratronics. Dr. Lipton has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Allergan/Abbvie. Dr. Lipton has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biohaven. Dr. Lipton has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eli Lilly. Dr. Lipton has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Lundbeck. Dr. Lipton has or had stock in Biohaven.Dr. Lipton has or had stock in Manistee.Dr. Lipton has or had stock in Axon.Dr. Lipton has or had stock in CoolTech. The institution of Dr. Lipton has received research support from Teva. The institution of Dr. Lipton has received research support from Amgen. The institution of Dr. Lipton has received research support from Allergan/Abbvie. The institution of Dr. Lipton has received research support from Gammacore. The institution of Dr. Lipton has received research support from Axsome. The institution of Dr. Lipton has received research support from Charleston Labs. The institution of Dr. Lipton has received research support from Eli Lilly. The institution of Dr. Lipton has received research support from Satsuma. The institution of Dr. Lipton has received research support from NIH . The institution of Dr. Lipton has received research support from Veterans Administration. Dr. Lipton has received publishing royalties from a publication relating to health care.

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