Abstract Details

Title "Mild" Sleep Disordered Breathing Has Significant Implications for the Treatment of Many Neurological Symptoms

Topic Sleep

Presentation(s) P05 - (-)

Poster/Presentation
Number 017

Objective

Background BACKGROUND: Previous studies have suggested a relationship between several neurologic symptoms including headache, cervical radiculopathy, lumbar radiculopathy and excessive daytime sleepiness and obstructive sleep apnea (OSA). However, these same symptoms could be associated with a milder form of sleep disordered breathing, UARS.

Design/Methods DESIGN/METHODS: This study is based on a retrospective review of 3034 consecutive patients who underwent polysomnography while being evaluated in a general neurology outpatient clinic. An odds ratio (OR) analysis was performed using primary symptoms, and UARS, and an innovative technique for visualization of the data was developed to depict these associations.

Results RESULTS: A RERA Index >=10 and Apnea-Hypopnea Index< 5 (definition of UARS) and primary/secondary variables yielded the following odds ratios: Sleep Related Movement Disorder (SRMD) - 12.3; Dizziness - 9.2; Fibromyalgia - 9.0; Migraine - 8.4; General Headache - 8.3; Cervical Radiculopathy - 7.9; Lumbar Radiculopathy - 5.8; Multiple Sclerosis - 5.3; and Restless Leg Syndrome (RLS) - 5.0.

Conclusions CONCLUSIONS: Many neurologic symptoms including Sleep Related Movement Disorder (SRMD), Dizziness, Fibromyalgia, Migraine, General Headache, Cervical Radiculopathy, Lumbar Radiculopathy, Multiple Sclerosis, and Restless Leg Syndrome (RLS) can be associated with mild sleep disordered breathing. The reason for these associations must await further evaluation.

Authors/Disclosures
Cord D. Huston, MD (University of Kansas Med Ctr, Psychiatry) PRESENTER	No disclosure on file
John A. Hunter	No disclosure on file
	No disclosure on file
Kenneth R. VanOwen, MD (Houston Neurological Inst)	No disclosure on file
	No disclosure on file
Vernon D. Rowe, MD, FAAN	No disclosure on file
Emmanuelle Waubant, MD, PhD, FAAN (USCF MS Center)	The institution of Dr. Waubant has received research support from NIH. The institution of Dr. Waubant has received research support from NMSS. The institution of Dr. Waubant has received research support from PCORI. The institution of Dr. Waubant has received research support from Race to Erase MS. The institution of Dr. Waubant has received research support from Roche. The institution of Dr. Waubant has received research support from Department of Defense. Dr. Waubant has received publishing royalties from a publication relating to health care.

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