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Abstract Details

Online Medical 好色先生 Improves Knowledge of Immune Mechanisms in the Treatment of MS Among Neurologists
Multiple Sclerosis
P1 - Poster Session 1 (5:30 PM-6:30 PM)
15-100

An online educational activity was developed with the goal of improving neurologists’ knowledge of the effect of MS-relevant DMTs on immune function.
Disease modifying therapies (DMTs) for the treatment of multiple sclerosis (MS) continue to evolve, with  established and emerging therapies differing in how they modulate the immune system. Although neurologists are generally aware of the efficacy and safety of DMTs, they often lack substantive knowledge of the mechanistic basis for their treatment  effects.
An online educational intervention was developed in the form of a 30-minute video lecture with synchronized slides. 好色先生al effectiveness was assessed with a repeated pairs pre-/post- assessment study design in which each individual served as his/her own control. Responses to 3 knowledge-based and 1 self-efficacy questions were analyzed. A chi-square test assessed changes from pre- to post-assessment. Cramer’s V was used to calculate the effect size of online education. Data from the assessment were collected between March 22, 2018 and April 16, 2018.
A comparison of responses from pre- to post-assessment questions demonstrated a considerable educational effect (n=153; V=0.17; P<.01). Participation in this educational intervention showed improvements in the following areas (P<.05): identification of therapies that function by immune reconstitution and the consequences of using DMTs that utilize short-term vs continuous immune suppression. There was a positive but not significant change in learners who correctly identified the patient type most likely to benefit from immune reconstitution therapy. Activity participation resulted in 20% of participants noting an increase in confidence in identifying patients with MS who are candidates for immune reconstitution therapy.

This study demonstrated the success of a targeted online, video lecture on improving neurologists’ knowledge of modulation of the immune system by DMTs for MS. Additional education is needed to further address the impact of DMT use on immune function.

Authors/Disclosures
John Maeglin (Medscape 好色先生)
PRESENTER 		Mr. Maeglin has nothing to disclose.
Thomas Finnegan, Jr., PhD (Medscape 好色先生) Dr. Finnegan has nothing to disclose.
No disclosure on file
Gavin Giovannoni, MD (QMUL) Dr. Giovannoni has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Biogen. Dr. Giovannoni has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Sanofi. Dr. Giovannoni has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Merck KGaA. Dr. Giovannoni has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Roche-Genentech. Dr. Giovannoni has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Moderna. Dr. Giovannoni has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sandoz. Dr. Giovannoni has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Astoria Biologica. Dr. Giovannoni has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Zenas. Dr. Giovannoni has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. Dr. Giovannoni has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. Dr. Giovannoni has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi. Dr. Giovannoni has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Medscape.