Abstract Details

Title The Processing Time for Recanalization and Size of Ischemic Lesions on DWI Is Related with Complete Reperfusion After Mechanical Thrombectomy

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P1 - Poster Session 1 (5:30 PM-6:30 PM)

Poster/Presentation
Number 3-018

Objective The purpose of this study was to determine significant factors to forecast the presence of complete reperfusion after mechanical thrombectomy based on multi-modal MRI.

Background Recent studies demonstrated that modified TICI 3 reperfusion have better functional outcomes than modified TICI 2b after mechanical thrombectomy in acute ischemic stroke with large vessel occlusion.

Design/Methods We investigated 96 consecutive patients with acute large intracranial artery occlusion of anterior circulation who based on multimodal MRI. Also, we compared clinical and radiologic parameters between patients with modified TICI 3 and those with modified TICI 0-2b.

Results Among 96 eligible subjects received mechanical thrombectomy, 39 patients (40.6%) showed complete reperfusion and 57 partial or non-reperfusion (m TICI 2b-26, m TICI 2a-9, m TICI 1-8, and m TICI 0-14) after mechanical thrombectomy. Patients with m TICI 3 had significantly smaller initial DWI lesion volume (p<0.01) and much shorter time interval from onset to reperfusion (p<0.01) than those patients with m TICI (0-2b). In multivariate analysis, smaller initial DWI volume (OR, 1.78; 95% CI, 1.23-2.57; p<0.01) and faster reperfusion time (OR, 1.07; 95% CI 1.01-1.14; p=0.015) had an independence significance for complete reperfusion after mechanical thrombectomy.

Conclusions

In this study, the ischemic lesion volume on DWI and faster processing time are critical factor to predict the state of complete reperfusion after mechanical thrombectomy.

Authors/Disclosures
Dong Jin Shin, MD (Gachon University Gil Hospital) PRESENTER	Dr. Shin has nothing to disclose.
Jae K. Cha	No disclosure on file

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